Stephen M Roberts

Stephen M Roberts, PhD

Professor; Program Director

Department: Department of Physiological Sciences
Business Phone: (352) 294-4514
Business Email: smroberts@ufl.edu

Accomplishments

UF Term Professorship
2017 · University of Florida
Technical Committee on Food and Chemical Safety
2014-2020 · ILSI North America
Chemical Assessment Advisory Committee
2012-2018 · U.S. EPA
Science Advisory Board (Chartered)
2006-2013 · U.S. EPA
Science Advisory Board
2006-2010 · National Center for Toxicological Research, U.S. FDA
Board of Scientific Counselors
2002-2005 · National Toxicology Program, DHHS
UF Research Foundation Professorship
2001 · University of Florida
FIFRA Scientific Advisory Panel
1999-2005 · U.S. EPA
Pfizer Award for Research Excellence
1998 · Pfizer

Research Profile

Mechanisms of drug and chemical toxicity; Cell defense mechanisms against toxicity; Toxicokinetics, particularly bioavailability of environmental contaminants; Risk assessment; Nanomaterial toxicity

Publications

2021
Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research.
Environmental toxicology and chemistry. 40(3):606-630 [DOI] 10.1002/etc.4890. [PMID] 33017053.
2020
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clams.
Regulatory toxicology and pharmacology : RTP. 117 [DOI] 10.1016/j.yrtph.2020.104759. [PMID] 32768666.
2020
Plasma l-indospicine and 3-nitropropionic acid in ponies fed creeping indigo: Comparison with results from an episode of presumptive creeping indigo toxicosis.
Equine veterinary journal. [DOI] 10.1111/evj.13415. [PMID] 33369767.
2020
Probabilistic risk assessment for high-end consumers of seafood on the northeastern Gulf coast.
Journal of exposure science & environmental epidemiology. 30(3):478-491 [DOI] 10.1038/s41370-019-0119-4. [PMID] 30728481.
2019
Bioaccessibility of polychlorinated dioxins and furans in soil from a Superfund site.
Chemosphere. 214:418-423 [DOI] 10.1016/j.chemosphere.2018.09.044. [PMID] 30268897.
2019
Derivation of a chronic reference dose for perfluorohexane sulfonate (PFHxS) for reproductive toxicity in mice.
Regulatory toxicology and pharmacology : RTP. 108 [DOI] 10.1016/j.yrtph.2019.104452. [PMID] 31487490.
2018
Incremental Sampling Methodology: Applications for Background Screening Assessments.
Risk analysis : an official publication of the Society for Risk Analysis. 38(1):194-209 [DOI] 10.1111/risa.12820. [PMID] 28556091.
2018
Influence of airborne particulates on respiratory tract deposition of inhaled toluene and naphthalene in the rat.
Inhalation toxicology. 30(1):19-28 [DOI] 10.1080/08958378.2018.1438539. [PMID] 29465005.
2018
Targeted heat activation of HSP promoters in the skin of mammalian animals and humans.
Cell stress & chaperones. 23(4):455-466 [DOI] 10.1007/s12192-018-0875-4. [PMID] 29417383.
2017
Influence of PEG coating on the oral bioavailability of gold nanoparticles in rats.
Drug delivery. 24(1):591-598 [DOI] 10.1080/10717544.2017.1282554. [PMID] 28222611.
2017
Molecular Mechanisms of Perfluorooctanoate-Induced Hepatocyte Apoptosis in Mice Using Proteomic Techniques.
Environmental science & technology. 51(19):11380-11389 [DOI] 10.1021/acs.est.7b02690. [PMID] 28885018.
2016
Applied Nanotoxicology.
International journal of toxicology. 35(1):5-16 [DOI] 10.1177/1091581816628484. [PMID] 26957538.
2016
Distribution and accumulation of 10 nm silver nanoparticles in maternal tissues and visceral yolk sac of pregnant mice, and a potential effect on embryo growth.
Nanotoxicology. 10(6):654-61 [DOI] 10.3109/17435390.2015.1107143. [PMID] 26593872.
2016
Effects of Source and Concentration on Relative Oral Bioavailability of Benzo(a)pyrene from Soil.
Environmental science & technology. 50(20):11274-11281 [PMID] 27617342.
View on: PubMed
2016
Oral Bioavailability, Bioaccessibility, and Dermal Absorption of PAHs from Soil-State of the Science.
Environmental science & technology. 50(5):2151-64 [DOI] 10.1021/acs.est.5b04110. [PMID] 26824144.
2015
Differential interferences with clinical chemistry assays by gold nanorods, and gold and silica nanospheres.
Nanotoxicology. 9(1):116-25 [DOI] 10.3109/17435390.2014.894151. [PMID] 24620736.
2015
Oral absorption of PEG-coated versus uncoated gold nanospheres: does agglomeration matter?
Particle and fibre toxicology. 12 [DOI] 10.1186/s12989-015-0085-5. [PMID] 25884802.
2014
Measurement of nanomaterials in foods: integrative consideration of challenges and future prospects.
ACS nano. 8(4):3128-35 [DOI] 10.1021/nn501108g. [PMID] 24673283.
2013
Derivation of a chronic reference concentration for decalin.
Regulatory toxicology and pharmacology : RTP. 66(1):38-46 [DOI] 10.1016/j.yrtph.2013.02.011. [PMID] 23454102.
2012
Influence of Suwannee River humic acid on particle properties and toxicity of silver nanoparticles.
Chemosphere. 89(1):96-101 [DOI] 10.1016/j.chemosphere.2012.04.024. [PMID] 22583785.
2012
The delivery of a health promotion intervention by a public health promotion specialist improves patient satisfaction in the emergency department.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 19(3):313-7 [DOI] 10.1111/j.1553-2712.2012.01293.x. [PMID] 22435864.
2010
Derived Reference Doses (RfDs) for the environmental degradates of the herbicides alachlor and acetochlor: results of an independent expert panel deliberation.
Regulatory toxicology and pharmacology : RTP. 57(2-3):220-34 [DOI] 10.1016/j.yrtph.2010.02.010. [PMID] 20206657.
2010
Nanoparticle characterization for cancer nanotechnology and other biological applications.
Methods in molecular biology (Clifton, N.J.). 624:39-65 [DOI] 10.1007/978-1-60761-609-2_4. [PMID] 20217588.
2008
Comparison of chlordecone and estradiol effects on splenic T-cells in (NZBxNZW)F(1) mice.
Toxicology letters. 183(1-3):1-9 [DOI] 10.1016/j.toxlet.2008.08.020. [PMID] 18951962.
2008
Differential Binding of Serum Proteins To Nanoparticles
International Journal of Nanotechnology. 5(1):92-115 [DOI] 10.1504/IJNT.2008.016550.
2008
Differential binding of serum proteins to nanoparticles. International Journal of Nanotechnology
International Journal of Nanotechnology. (5):92-115
2008
Differential binding of serum proteins to nanoparticles. International Journal of Nanotechnology
International Journal of Nanotechnology. (5):92-115
2008
Prevention of chemotherapy-induced alopecia in rodent models.
Cell stress & chaperones. 13(1):31-8 [DOI] 10.1007/s12192-007-0005-1. [PMID] 18347939.
2007
Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and estradiol in (NZBxNZW)F1 mice.
Toxicological sciences : an official journal of the Society of Toxicology. 99(1):141-52 [PMID] 17578864.
View on: PubMed
2007
Body weight distributions for risk assessment.
Risk analysis : an official publication of the Society for Risk Analysis. 27(1):11-26 [PMID] 17362397.
View on: PubMed
2007
Diminished prolactin from chlordecone treatment in ovariectomized (NZBxNZW)F(1) mice.
International immunopharmacology. 7(13):1808-12 [PMID] 17996692.
View on: PubMed
2007
Relative oral bioavailability of arsenic from contaminated soils measured in the cynomolgus monkey.
Toxicological sciences : an official journal of the Society of Toxicology. 95(1):281-8 [PMID] 17005634.
View on: PubMed
2006
Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice.
Toxicology. 218(2-3):81-9 [PMID] 16309813.
View on: PubMed
2006
Increased hepatotoxicity of acetaminophen in Hsp70i knockout mice.
Toxicology and applied pharmacology. 210(1-2):157-62 [PMID] 16280147.
View on: PubMed
2006
Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation.
Toxicological sciences : an official journal of the Society of Toxicology. 90(2):296-303 [PMID] 16407094.
View on: PubMed
2005
Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.
Environmental health perspectives. 113(3):323-8 [PMID] 15743722.
View on: PubMed
2005
Heat shock proteins and acquired resistance to uranium nephrotoxicity.
Toxicology. 206(1):59-73 [PMID] 15590109.
View on: PubMed
2005
Manipulating heat shock protein expression in laboratory animals.
Methods (San Diego, Calif.). 35(2):149-57 [PMID] 15649841.
View on: PubMed
2005
Novel gene switches for targeted and timed expression of proteins of interest.
Molecular therapy : the journal of the American Society of Gene Therapy. 12(2):290-8 [PMID] 15925546.
View on: PubMed
2003
Cocaine-protein targets in mouse liver.
Biochemical pharmacology. 66(1):105-13 [PMID] 12818370.
View on: PubMed
2002
Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride).
Regulatory toxicology and pharmacology : RTP. 35(1):44-55 [PMID] 11846635.
View on: PubMed
2002
Measurement of arsenic bioavailability in soil using a primate model.
Toxicological sciences : an official journal of the Society of Toxicology. 67(2):303-10 [PMID] 12011490.
View on: PubMed

Grants

Jul 2021 ACTIVE
Toxicological Support Services 2021-2022
Role: Co-Investigator
Funding: FL DEPT OF HLTH ENVIROMENTAL HEALTH
Nov 2020 ACTIVE
Chemical Measures of PAH Bioavailability to Improve Human Health Risk Assessment of Contaminated Sites – In Vivo Studies for Naval Information Warfare Center (NIWC), Pacific, located in San Diego, CA
Role: Principal Investigator
Funding: US ARMY CORPS OF ENGINEERS
Jul 2020 ACTIVE
FL DEP HW677 Toxicological Support Services
Role: Co-Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT
Jul 2020 ACTIVE
FL DEP HW678 – Toxicological Support Services
Role: Co-Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT via US ENVIRONMENTAL PRO AGCY
Jan 2020 – Aug 2020
The provision of research and evaluation to determine the short and long-term human health impacts from harmful algal blooms (HABs)
Role: Co-Investigator
Funding: FL DEPT OF HLTH
Nov 2019 – Mar 2020
Toxicological support services
Role: Co-Investigator
Funding: FL DEPT OF HLTH ENVIROMENTAL HEALTH
Apr 2019 ACTIVE
Development of a Community-Based Lead Risk Mitigation Model
Role: Co-Investigator
Funding: CORNWELL RESEARCH GROUP via US ENVIRONMENTAL PRO AGCY
Apr 2018 ACTIVE
PBET Calibration and In Vivo Feeding Trial Implementation for Skeet Range-Derived PAHs
Role: Principal Investigator
Funding: ALLOY via NAVAL FACILITIES ENG COMMAND
Feb 2018 ACTIVE
Miami Dade Multi Sponsors
Role: Principal Investigator
Funding: MIAMI-DADE CNTY
Apr 2017 – Mar 2019
Rapid risk assessment of chronic domoic acid exposure in WA razor clam harvesters
Role: Co-Investigator
Funding: UNIV OF MARYLAND BALTIMORE via NATL INST OF HLTH NIEHS
Mar 2017 – Sep 2017
Dioxin Bioaccessibility Assessment for the American Creosote Works Site Center for Environmental & Human Toxicology
Role: Principal Investigator
Funding: GEOSYNTEC via FL DEPT OF ENVIRONMENTAL PROTECT
May 2014 – Dec 2017
Influence of Particulates on Pulmonary Deposition of VOCs
Role: Principal Investigator
Funding: ELECTRIC POWER RES INST
Oct 2012 – Jan 2018
Miami Dade Multiple Sponsors
Role: Principal Investigator
Funding: MULTIPLE SPONSORS
Jun 2011 – Apr 2017
Health Impact of Deepwater Horizon Spill in Eastern Gulf Coast Communities
Role: Project Manager
Funding: NATL INST OF HLTH NIEHS
Aug 2010 – Jun 2020
Toxicological Support Services
Role: Principal Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT
Aug 2010 – Jun 2020
Toxicological Support Services
Role: Principal Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT via US ENVIRONMENTAL PRO AGCY
Apr 2007 ACTIVE
Center of Excellence – Center for Nano-Biosensors
Role: Project Manager
Funding: STATE UNIV SYS OF FL BOARD OF GOVERNORS

Education

NIH Postdoctoral fellow
1978-1980 · School of Pharmacy, SUNY Buffalo
Doctor of Philosophy
1977 · College of Medicine, University of Utah
Bachelor of Science in Pharmacy
1973 · College of Pharmacy, Oregon State University

Teaching Profile

Courses Taught
2020-2021
PAS5026 Pharmacotherapeu 2
2008-2010,2015-2021
VME6602 General Toxicology
2008,2015-2021
VME6605 Toxic Substances
2006,2009-2018
VME6607 Human Health Risk Assessment
2018
VME7980 Research for Doctoral Dissertation
2016
VME6932 Seminar in Physiological Sciences
2010,2012-2015,2015
PHC6601 Seminar in Contemporary Public Health Issues
2011-2013,2015
PHC6946 Public Health Internship
2013-2014
BMS6031 Foundations of Med
2006-2009,2011
VME4906 Problems in Veterinary Science
2006
VME6934 Topics in Veterinary Medical Sciences

Contact Details

Phones:
Business:
(352) 294-4514
Emails:
Business:
smroberts@ufl.edu