Roger L Reep

Roger L Reep,

EMERITUS PROF

Department: Department of Physiological Sciences
Business Phone: (352) 562-9449
Business Email: reepr@ufl.edu

Accomplishments

Teacher of the Year
2010 · College of Veterinary Medicine, University of Florida
Choice Outstanding Academic Book Award for The Florida Manatee
2007 · unknown
Manatee Hero Medal
2006 · Save the Manatee Club
Award
2005 · University of Florida Research Foundation
Pfizer Award for Research Excellence
2004 · University of Florida
Florida’s Finest award
1994 · Governor of Florida
Agvet Award for Teaching Creativity
1991 · MSD Animal Health

Research Profile

Manatee tactile hairs: Manatees possess specialized tactile bristles and hairs which are distributed over the entire body surface. We hypothesize that Sirenia have developed a mammalian version of the lateral line system which detects water currents, approaching animals and other stimuli producing underwater mechanovibratory signals not detectable through the auditory system. In collaboration with colleagues Dr. Gordon Bauer (New College) and Dr. David Mann (University of South Florida), graduate student Joe Gaspard is performing behavioral experiments on two captive manatees at Mote Marine Laboratory to investigate the functional capacity of this system.

Manatee brain and body growth: Adult manatees have small brains relative to their body size, when compared to other mammals. However, this may reflect prolonged body growth rather than diminished brain size per se. Graduate student Alex Costidis is investigating growth dynamics of brain and body in Florida manatees, and performing a comparative analysis to determine if manatees exhibit prolonged body growth compared to other similarly sized marine mammals.

Manatee brain pathways: We are using postmortem axonal tracing (DiI) to investigate neural connections among regions of the brainstem and thalamus that process tactile information. Understanding this organization will allow us to gain further insight into the means by which information from the tactile hairs travels in the manatee brain.

Rodent model of hemispatial neglect: Neglect occurs in humans after cortical infarct in a high percentage of cases of right hemisphere stroke. Over the past 25 years, we have collaborated with Dr. Jim Corwin at Northern Illinois University to develop a rat model to investigate the circuitry and pharmacology mediating directed attention and its dysfunctional state, contralateral neglect, and to explore potential therapies for inducing neural repair and functional recovery. Normal directed attention is mediated by circuitry involving specific areas of cerebral cortex, striatum and thalamus. Currently, undergraduate students Billy Conte, Tamara Stiep and Tobias Schmid are investigating neuronal connections of the lateral posterior thalamic nucleus and cerebral cortical areas AGm and PPC, part of the circuitry related to neglect. These studies involve the use of axonal tracers and image analysis.

Publications

2018
Thromboelastography in wild Florida manatees (Trichechus manatus latirostris).
Veterinary clinical pathology. 47(2):227-232 [DOI] 10.1111/vcp.12599. [PMID] 29522245.
2017
Detection of hydrodynamic stimuli by the postcranial body of Florida manatees (Trichechus manatus latirostris).
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 203(2):111-120 [DOI] 10.1007/s00359-016-1142-8. [PMID] 28194485.
2017
Detection of hydrodynamic stimuli by the postcranial body of Florida manatees (Trichechus manatus latirostris).
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 203(2):111-120 [DOI] 10.1007/s00359-016-1142-8. [PMID] 28194485.
2017
Identifying coagulopathies in the pathophysiology of cold stress syndrome in the Florida manatee Trichechus manatus latirostris.
Diseases of aquatic organisms. 125(3):179-188 [DOI] 10.3354/dao03149. [PMID] 28792416.
2017
PROPOSAL AND APPLICATION OF A NOVEL DISSEMINATED INTRAVASCULAR COAGULATION SCORING SYSTEM IN THE FLORIDA MANATEE (TRICHECHUS MANATUS LATIROSTRIS).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 48(1):152-158 [DOI] 10.1638/2016-0050.1. [PMID] 28363081.
2016
Evolution of cytoarchitectural landscapes in the mammalian isocortex: Sirenians (Trichechus manatus) in comparison with other mammals.
The Journal of comparative neurology. 524(4):772-82 [DOI] 10.1002/cne.23864. [PMID] 26223206.
2016
Golgi Analysis of Neuron Morphology in the Presumptive Somatosensory Cortex and Visual Cortex of the Florida Manatee (Trichechus manatus latirostris).
Brain, behavior and evolution. 87(2):105-16 [DOI] 10.1159/000445495. [PMID] 27166161.
2016
Normal Hemostatic Profiles and Coagulation Factors in Healthy Free-Living Florida Manatees ( Trichechus manatus latirostris).
Journal of wildlife diseases. 52(4):907-911 [PMID] 27525595.
View on: PubMed
2015
Eight-choice sound localization by manatees: performance abilities and head related transfer functions.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 201(2):249-59 [DOI] 10.1007/s00359-014-0973-4. [PMID] 25533765.
2015
Elaboration and Innervation of the Vibrissal System in the Rock Hyrax (Procavia capensis).
Brain, behavior and evolution. 85(3):170-88 [DOI] 10.1159/000381415. [PMID] 26022696.
2015
In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis.
Brain structure & function. 220(1):361-83 [DOI] 10.1007/s00429-013-0660-1. [PMID] 24178679.
2015
Neuron Types in the Presumptive Primary Somatosensory Cortex of the Florida Manatee (Trichechus manatus latirostris).
Brain, behavior and evolution. 86(3-4):210-31 [DOI] 10.1159/000441964. [PMID] 26613530.
2014
Comparative neuronal morphology of the cerebellar cortex in afrotherians, carnivores, cetartiodactyls, and primates.
Frontiers in neuroanatomy. 8 [DOI] 10.3389/fnana.2014.00024. [PMID] 24795574.
2014
Comparative neuronal morphology of the cerebellar cortex in afrotherians, carnivores, cetartiodactyls, and primates.
Frontiers in neuroanatomy. 8 [DOI] 10.3389/fnana.2014.00024. [PMID] 24795574.
2013
Detection of hydrodynamic stimuli by the Florida manatee (Trichechus manatus latirostris).
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 199(6):441-50 [DOI] 10.1007/s00359-013-0822-x. [PMID] 23660811.
2013
Ecology and Conservation of the Sirenia
Marine Mammal Science. 29(4):780-782 [DOI] 10.1111/mms.12062.
2013
Post-Cranial Hairs in Four Families of Bats
Acta Chiropterologica. 15:153-161 [DOI] 10.3161/150811013X667957.
2012
Audiogram and auditory critical ratios of two Florida manatees (Trichechus manatus latirostris).
The Journal of experimental biology. 215(Pt 9):1442-7 [DOI] 10.1242/jeb.065649. [PMID] 22496279.
2011
Mammalian tactile hair: divergence from a limited distribution.
Annals of the New York Academy of Sciences. 1225:90-100 [DOI] 10.1111/j.1749-6632.2011.05979.x. [PMID] 21534996.
2011
Manatee vibrissae: evidence for a “lateral line” function.
Annals of the New York Academy of Sciences. 1225:101-9 [DOI] 10.1111/j.1749-6632.2011.05992.x. [PMID] 21534997.
2010
Developmental uterine anomalies in cats and dogs undergoing elective ovariohysterectomy.
Journal of the American Veterinary Medical Association. 237(5):542-6 [DOI] 10.2460/javma.237.5.542. [PMID] 20807131.
2010
Estimating Body Size of Fossil Sirenians
Marine Mammal Science. 26(4):937-959 [DOI] 10.1111/j.1748-7692.2010.00384.x.
2010
Phrenic nerve afferent activation of neurons in the cat SI cerebral cortex.
The Journal of physiology. 588(Pt 5):873-86 [DOI] 10.1113/jphysiol.2009.181735. [PMID] 20064855.
2009
Conservation and diversity of Foxp2 expression in muroid rodents: functional implications.
The Journal of comparative neurology. 512(1):84-100 [DOI] 10.1002/cne.21881. [PMID] 18972576.
2009
Cortical connections of the rat lateral posterior thalamic nucleus.
Brain research. 1264:39-56 [DOI] 10.1016/j.brainres.2009.01.024. [PMID] 19368845.
2009
Four-choice sound localization abilities of two Florida manatees, Trichechus manatus latirostris.
The Journal of experimental biology. 212(Pt 13):2105-12 [DOI] 10.1242/jeb.029033. [PMID] 19525437.
2009
Multiple neuroanatomical tract-tracing using fluorescent Alexa Fluor conjugates of cholera toxin subunit B in rats.
Nature protocols. 4(8):1157-66 [DOI] 10.1038/nprot.2009.93. [PMID] 19617887.
2009
Organization of the corticostriatal projection from rat medial agranular cortex to far dorsolateral striatum.
Brain research. 1280:69-76 [DOI] 10.1016/j.brainres.2009.05.044. [PMID] 19465007.
2009
Posterior parietal cortex as part of a neural network for directed attention in rats.
Neurobiology of learning and memory. 91(2):104-13 [DOI] 10.1016/j.nlm.2008.08.010. [PMID] 18824116.
2009
The efficacy of the fluorescent conjugates of cholera toxin subunit B for multiple retrograde tract tracing in the central nervous system.
Brain structure & function. 213(4-5):367-73 [DOI] 10.1007/s00429-009-0212-x. [PMID] 19621243.
2008
Material Properties of Manatee Rib Bone
Journal of Zoology. 274(2):150-159 [DOI] 10.1111/j.1469-7998.2007.00366.x.
2008
Nogo-A inhibition induces recovery from neglect in rats.
Behavioural brain research. 187(2):262-72 [PMID] 17963852.
View on: PubMed
2008
Quantification of synaptic density in corticostriatal projections from rat medial agranular cortex.
Brain research. 1233:27-34 [DOI] 10.1016/j.brainres.2008.07.059. [PMID] 18691563.
2008
Quantitative Fractography for Estimating Whole Bone Properties of Manatee Rib Bones
Journal of Materials Science. 43(6):2026-2034 [DOI] 10.1007/s10853-007-2422-z.
2008
Striatal projections from the rat lateral posterior thalamic nucleus.
Brain research. 1204:24-39 [DOI] 10.1016/j.brainres.2008.01.094. [PMID] 18342841.
2008
Topography in the projections of lateral posterior thalamus with cingulate and medial agranular cortex in relation to circuitry for directed attention and neglect.
Brain research. 1240:87-95 [DOI] 10.1016/j.brainres.2008.09.013. [PMID] 18817759.
2007
Adaptations in the structure and innervation of follicle-sinus complexes to an aquatic environment as seen in the Florida manatee (Trichechus manatus latirostris).
The Journal of comparative neurology. 504(3):217-37 [PMID] 17640045.
View on: PubMed
2007
Digesta passage rates in the Florida manatee (Trichechus manatus latirostris).
Zoo biology. 26(6):503-15 [DOI] 10.1002/zoo.20150. [PMID] 19360597.
2007
Somatosensory areas of manatee cerebral cortex: histochemical characterization and functional implications.
Brain, behavior and evolution. 69(1):20-36 [PMID] 16912474.
View on: PubMed
2007
Somatosensory nuclei of the manatee brainstem and thalamus.
Anatomical record (Hoboken, N.J. : 2007). 290(9):1138-65 [PMID] 17722080.
View on: PubMed
2007
The limbic system in Mammalian brain evolution.
Brain, behavior and evolution. 70(1):57-70 [PMID] 17409735.
View on: PubMed
2007
Topographical organization of the facial motor nucleus in Florida manatees (Trichechus manatus latirostris).
Brain, behavior and evolution. 70(3):164-73 [PMID] 17595536.
View on: PubMed
2006
Application of fracture mechanics to failure in manatee rib bone.
Journal of biomechanical engineering. 128(3):281-9 [PMID] 16706577.
View on: PubMed
2006
Fracture toughness of manatee rib and bovine femur using a chevron-notched beam test.
Journal of biomechanics. 39(6):1066-74 [PMID] 16549096.
View on: PubMed
2005
Corneal vascularization in the Florida manatee (Trichechus manatus latirostris) and three-dimensional reconstruction of vessels.
Veterinary ophthalmology. 8(2):89-99 [PMID] 15762922.
View on: PubMed
2005
Overlap and interdigitation of cortical and thalamic afferents to dorsocentral striatum in the rat.
Brain research. 1036(1-2):90-100 [PMID] 15725405.
View on: PubMed
2005
Pathologic and immunohistochemical findings in hypothalamic and mesencephalic regions in the pah(enu2) mouse model for phenylketonuria.
Pediatric research. 58(2):283-7 [PMID] 16055931.
View on: PubMed
2005
Temporal resolution of the Florida manatee (Trichechus manatus latirostris) auditory system.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 191(10):903-8 [PMID] 16001184.
View on: PubMed
2004
A rodent model for investigating the neurobiology of contralateral neglect.
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. 17(4):191-4 [PMID] 15622013.
View on: PubMed
2003
Effects of light deprivation on recovery from neglect and extinction induced by unilateral lesions of the medial agranular cortex and dorsocentral striatum.
Behavioural brain research. 138(2):165-78 [PMID] 12527447.
View on: PubMed
2003
Infusion of apomorphine into the dorsocentral striatum produces acute drug-induced recovery from neglect produced by unilateral medial agranular cortex lesions in rats.
Behavioural brain research. 143(2):147-57 [PMID] 12900041.
View on: PubMed
2003
Seizure-alert dogs: a review and preliminary study.
Seizure. 12(2):115-20 [PMID] 12566236.
View on: PubMed
2003
The associative striatum: cortical and thalamic projections to the dorsocentral striatum in rats.
Brain research. 968(1):1-14 [PMID] 12644259.
View on: PubMed
2003
The associative striatum: organization of cortical projections to the dorsocentral striatum in rats.
The Journal of comparative neurology. 467(3):271-92 [PMID] 14608594.
View on: PubMed
2002
Tactile hairs on the postcranial body in Florida manatees: a Mammalian lateral line?
Brain, behavior and evolution. 59(3):141-54 [PMID] 12119533.
View on: PubMed
2002
Unilateral destruction of the dorsocentral striatum in rats produces neglect but not extinction to bilateral simultaneous stimulation.
Behavioural brain research. 136(2):375-87 [PMID] 12429399.
View on: PubMed
2001
Microanatomy of facial vibrissae in the Florida manatee: the basis for specialized sensory function and oripulation.
Brain, behavior and evolution. 58(1):1-14 [PMID] 11799274.
View on: PubMed
2000
Cortical layer VII and persistent subplate cells in mammalian brains.
Brain, behavior and evolution. 56(4):212-34 [PMID] 11155000.
View on: PubMed
1999
Forebrain connections of medial agranular cortex in the prairie vole, Microtus ochrogaster.
Experimental brain research. 126(3):336-50 [PMID] 10382619.
View on: PubMed
1999
Interstitial cells of the white matter in the inferior parietal cortex in schizophrenia: An unbiased cell-counting study.
Synapse (New York, N.Y.). 34(2):95-102 [PMID] 10502308.
View on: PubMed
1999
Topographic organization of the striatal and thalamic connections of rat medial agranular cortex.
Brain research. 841(1-2):43-52 [PMID] 10546986.
View on: PubMed
1998
Change in size of replaced amalgam restorations: a methodological study.
Operative dentistry. 23(5):272-7 [PMID] 9863449.
View on: PubMed
1997
Disconnection of medial agranular and posterior parietal cortex produces multimodal neglect in rats.
Behavioural brain research. 86(1):41-7 [PMID] 9105580.
View on: PubMed
1996
Layer VII and the gray matter trajectories of corticocortical axons in rats.
Anatomy and embryology. 194(6):581-93 [PMID] 8957534.
View on: PubMed
1996
Neuronal connections of orbital cortex in rats: topography of cortical and thalamic afferents.
Experimental brain research. 111(2):215-32 [PMID] 8891652.
View on: PubMed
1995
Manatee cerebral cortex: cytoarchitecture of the caudal region in Trichechus manatus latirostris.
Brain, behavior and evolution. 45(1):1-18 [PMID] 7866767.
View on: PubMed
1994
Bilateral destruction of the ventrolateral orbital cortex produces allocentric but not egocentric spatial deficits in rats.
Behavioural brain research. 61(1):79-86 [PMID] 8031498.
View on: PubMed
1994
Phylogeny through brain traits: more characters for the analysis of mammalian evolution.
Brain, behavior and evolution. 43(6):319-47 [PMID] 8044673.
View on: PubMed
1994
Rat posterior parietal cortex: topography of corticocortical and thalamic connections.
Experimental brain research. 100(1):67-84 [PMID] 7813654.
View on: PubMed
1994
Thalamocortical projections activated by phrenic nerve afferents in the cat.
Neuroscience letters. 180(2):114-8 [PMID] 7535404.
View on: PubMed
1993
Cerebral cortical evoked potentials elicited by cat intercostal muscle mechanoreceptors.
Journal of applied physiology (Bethesda, Md. : 1985). 74(2):799-804 [PMID] 8458798.
View on: PubMed
1992
Thalamocortical connections of rat posterior parietal cortex.
Neuroscience letters. 143(1-2):237-42 [PMID] 1436673.
View on: PubMed
1990
Regional brain morphometry and lissencephaly in the Sirenia.
Brain, behavior and evolution. 35(4):185-94 [PMID] 2379080.
View on: PubMed
1990
Topographic organization in the corticocortical connections of medial agranular cortex in rats.
The Journal of comparative neurology. 294(2):262-80 [PMID] 2332532.
View on: PubMed
1989
Acetylcholinesterase stain intensity variation in the rat dentate gyrus: a quantitative description based on digital image analysis.
Neuroscience. 33(1):203-21 [PMID] 2601856.
View on: PubMed
1989
Manatee cerebral cortex: cytoarchitecture of the frontal region in Trichechus manatus latirostris.
Brain, behavior and evolution. 34(6):365-86 [PMID] 2611642.
View on: PubMed
1989
Production and characterization of neglect in rats with unilateral lesions of ventrolateral orbital cortex.
Experimental neurology. 105(3):287-99 [PMID] 2767200.
View on: PubMed
1988
An accurate method for automated counting of silver grains in autoradiographs.
Computers and biomedical research, an international journal. 21(3):244-67 [PMID] 3383555.
View on: PubMed
1988
Combined retrograde and anterograde tracing of neuronal connections: Fluoro-Gold and autoradiography.
Journal of neuroscience methods. 23(1):1-5 [PMID] 2450264.
View on: PubMed
1988
Hemispheric asymmetry in neglect produced by unilateral lesions of dorsomedial prefrontal cortex in rats.
Experimental neurology. 102(2):199-209 [PMID] 3181358.
View on: PubMed
1988
Layer VII of rodent cerebral cortex.
Neuroscience letters. 90(1-2):15-20 [PMID] 3412636.
View on: PubMed
1987
Efferent connections of the rostral portion of medial agranular cortex in rats.
Brain research bulletin. 19(2):203-21 [PMID] 2822206.
View on: PubMed
1985
Avoidance and escape components of leg position learning in the prothoracic and mesothoracic ganglia of the cockroach, P. americana.
Physiology & behavior. 34(1):129-32 [PMID] 4034689.
View on: PubMed
1985
Projection of phrenic nerve afferents to the cat sensorimotor cortex.
Brain research. 328(1):150-3 [PMID] 3971173.
View on: PubMed
1985
The three-dimensional morphology of afferent terminal fields in the rat dentate gyrus: periodic variation.
The Journal of comparative neurology. 234(3):334-43 [PMID] 3988988.
View on: PubMed
1984
Afferent connections of medial precentral cortex in the rat.
Neuroscience letters. 44(3):247-52 [PMID] 6728294.
View on: PubMed
1984
Relationship between prefrontal and limbic cortex: a comparative anatomical review.
Brain, behavior and evolution. 25(1):5-80 [PMID] 6398115.
View on: PubMed
1982
Afferent connections of dorsal and ventral agranular insular cortex in the hamster Mesocricetus auratus.
Neuroscience. 7(5):1265-88 [PMID] 7110587.
View on: PubMed
1982
Efferent connections of dorsal and ventral agranular insular cortex in the hamster, Mesocricetus auratus.
Neuroscience. 7(11):2609-35 [PMID] 7155344.
View on: PubMed
1980
Neuronal pathways involved in transfer of information related to leg position learning in the cockroach, P. americana.
Physiology & behavior. 24(3):501-13 [PMID] 7375571.
View on: PubMed

Education

Doctor of Philosophy in Zoology-Neuroscience
1978 · Michigan State University
Bachelor of Science in Physics (cum laude)
1973 · Michigan State University

Teaching Profile

Courses Taught
2020-2021
VEM5378C Seavet Clin Training
2014
VEM5115 Veterinary Histology
2014
VEM5373 Manatee Hlth and Cons
2014
VEM5372 Aq Wildlife Health
2011-2012,2014
VEM5112 Animal Systems 3
2009-2012,2014
VME4906 Problems in Veterinary Science
2014
VME3001 The Dog
2007-2008,2010-2014,2012-2014,2014
GMS6074 Comparative and Evolutionary Neurobiology
2006-2007,2009-2013
VEM5113 Embryol Dev Tis/Org
2009-2013
VEM5110 Animal Systems 1
2006,2011-2012
VME6934 Topics in Veterinary Medical Sciences
2011
VME6932 Seminar in Physiological Sciences
2011
VEM5111 Animal Systems 2
2008-2010
VME6905 Problems in Veterinary Medical Sciences
2009
VME6940 Supervised Teaching
2008
ZOO6927 Special Topics

Contact Details

Phones:
Business:
(352) 562-9449
Emails:
Business:
reepr@ufl.edu

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