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UF Health University of Florida
College of Veterinary Medicine UNIVERSITY of FLORIDA
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Julie M Moore

Julie M Moore,

Professor

Department: Department of Infectious Diseases & Immunology
Business Phone: (352) 294-4111
Business Email: juliemoore@ufl.edu

On This Page

Accomplishments

Teaching Profile

Courses Taught

  1. VME4906 – Problems in Veterinary Science

    College of Veterinary Medicine

  2. VME6934 – Topics in Veterinary Medical Sciences

    College of Veterinary Medicine

  3. VME6933 – Seminar in Infectious Diseases and Experimental Pathology

    College of Veterinary Medicine

  4. VEM5131 – Vet Molecular Biology

    College of Veterinary Medicine

  5. VME7980 – Research for Doctoral Dissertation

    College of Veterinary Medicine

  6. VME7979 – Advanced Research

    College of Veterinary Medicine

Research Profile

Dr. Moore’s research interests center on understanding the immunopathogenesis of malaria and advancing knowledge of placental biology through study of malaria in pregnancy. The laboratory uses a combination of field-based studies (in Kenya), mouse models and in vitro models of villous placenta-malaria parasite interactions to elucidate the complex interactions between the parasite, the placenta and maternal physiology that result in compromised pregnancy. Of particular interest is the intersection between malaria-driven inflammation, coagulation and oxidative stress in the placenta, and how these contribute to cell death and dysfunctional placenta. Similar mechanistic studies are also being conducted in models of cerebral malaria. The lab is also exploring, through collaborative studies with Drs. Connie Mulligan and Chris Dutton at UF, how maternal factors such as pre-natal stress impact the development of the infant gut microbiome and how such impacts further determine infant susceptibility to malaria in the first year of life. The latter studies compliment work in mouse models that shows modulation of the gut microbiome determines both the course of malaria infection and fetal outcomes. The goals of these projects are to advance understanding of the fundamental biology of the host-parasite interaction in malaria and identify novel host-directed therapeutic options for mitigating the effects of malaria infection during pregnancy and other forms of severe malaria.

Publications

Academic Articles

Grants

  1. AB SCIEX QTRAP 7500 LC MS/MS

    Active

    Role:
    Other
    Funding:
    NATL INST OF HLTH OD

  2. Exploring the etiology of oxidative damage and cell death in placental malaria

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIAID

  3. OR-DRPD-ROF2019: Prenatal stress, the gut microbiota and infant susceptibility to malaria

    Role:
    Principal Investigator
    Funding:
    UF RESEARCH

Education

  1. Doctor of Philosophy in Biomedical Science

    University of Connecticut Health Center

Contact Details

Phones:
Business:
(352) 294-4111
Emails:
Business:
juliemoore@ufl.edu
Addresses:
Business Mailing:
PO Box 110880
 GAINESVILLE FL 32611
Business Street:
V2-158 Veterinary Academic Building
 GAINESVILLE FL 32611