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UF Health University of Florida

College of Veterinary Medicine

UNIVERSITY of FLORIDA

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John W Harvey

John W Harvey,

Professor Emeritus

Department: Department of Comparative, Diagnostic & Population Medicine
Business Phone: (352) 294-4277
Business Email: jwharvey@ufl.edu

Teaching Profile

Courses Taught
2006-2007,2017-2019,2019
VEM5110 Animal Systems 1
2014-2015
VEM5303 Small Anim Hematology
2007,2011-2014
VEM5112 Animal Systems 3
2010
VME6905 Problems in Veterinary Medical Sciences
2006-2007
VEM5221 Intro Clinic Pathol
2007
VEM5111 Animal Systems 2

Research Profile

Areas of research interest and publications have included erythrocyte metabolism of domestic animals, Heinz body hemolytic anemias, serum haptoglobin alterations in disease states, iron deficiency anemia, methemoglobinemias, myeloproliferative and lymphoproliferative disorders, developmental hematology and iron metabolism in foals, hematology and iron metabolism of pregnant mares, and infectious agents of blood cells. Infectious agents studied include Mycoplasma haemofelis, Cytauxzoon felis, Anaplasma platys, Ehrlichia canis, Anaplasma phagocytophilum, Babesia canis and Leishmania donovani.

A longstanding area of interest is inherited defects of erythrocyte metabolism in domestic animals. Publications have resulted from in depth studies of clinical cases of pyruvate kinase deficiency in dogs, methemoglobin reductase deficiency in dogs and cats, glucose-6-phosphate dehydrogenase deficiency in horses, and flavin adenine dinucleotide deficiency in horses. Extensive experimental studies have been conducted on erythrocytes and muscles from adult and neonatal phosphofructokinase-deficient dogs. A new area of study focuses on the clinical chemistry and hematology of Florida manatees.

Areas of Interest
  • Hematology
Open Researcher and Contributor ID (ORCID)

0000-0002-6125-0041

Publications

2022
Left shift and toxic change in heterophils and neutrophils of non‐mammalian vertebrates: A comparative review, image atlas, and practical considerations
Veterinary Clinical Pathology. [DOI] 10.1111/vcp.13117.
Publisher’s Site
2022
Proposal for standardized classification of left shift, toxic change, and increased nuclear segmentation in heterophils and neutrophils in non-mammalian vertebrates.
Veterinary clinical pathology. [DOI] 10.1111/vcp.13120. [PMID] 35199859.
PubMed · Publisher’s Site
2021
Whip-like heterophil projections: Best in show.
Veterinary clinical pathology. [DOI] 10.1111/vcp.13044. [PMID] 34189754.
PubMed · Publisher’s Site
2019
Serum Iron Analytes in Healthy and Diseased Florida Manatees (Trichechus manatus latirostris).
Journal of comparative pathology. [DOI] 10.1016/j.jcpa.2019.10.006. [PMID] 31812174.
PubMed · Publisher’s Site
2018
Serum proteins in healthy and diseased Florida manatees (Trichechus manatus latirostris)
Comparative Clinical Pathology. [DOI] 10.1007/s00580-018-2797-z.
Publisher’s Site
2018
What is your diagnosis? Cutaneous nodules and atypical blood cells in a dog.
Veterinary clinical pathology. [DOI] 10.1111/vcp.12586. [PMID] 29469994.
PubMed · Publisher’s Site
2017
Bone Marrow Aspirate Evaluation.
The Veterinary clinics of North America. Small animal practice. [DOI] 10.1016/j.cvsm.2016.07.003. [PMID] 27720279.
PubMed · Publisher’s Site
2017
The feline blood film.
Journal of feline medicine and surgery. [DOI] 10.1177/1098612X17706471. [PMID] 28592222.
PubMed · Publisher’s Site
2017
The feline blood film.
Journal of feline medicine and surgery. [DOI] 10.1177/1098612X17706466. [PMID] 28438085.
PubMed · Publisher’s Site
2017
Whip-like heterophil projections in consecutive blood films from an injured gopher tortoise (Gopherus polyphemus) with systemic inflammation.
The veterinary quarterly. [DOI] 10.1080/01652176.2017.1325538. [PMID] 28460581.
PubMed · Publisher’s Site
2015
Letter to the Editor: Heinz bodies and erythrophagocytosis in the peripheral blood of loggerhead sea turtles.
Journal of experimental zoology. Part A, Ecological genetics and physiology. [DOI] 10.1002/jez.1925. [PMID] 25777323.
PubMed · Publisher’s Site
2014
Congenital methemoglobinemia in a dog with a promoter deletion and a nonsynonymous coding variant in the gene encoding cytochrome b₅.
Journal of veterinary internal medicine. [DOI] 10.1111/jvim.12423. [PMID] 25145387.
PubMed · Publisher’s Site
2013
Recognition of Professor Kaneko (1924-2013) in Memoriam
Veterinary Clinical Pathology. [DOI] 10.1111/vcp.12049.
Publisher’s Site
2012
Hemolytic anemia in dogs and cats due to erythrocyte enzyme deficiencies.
The Veterinary clinics of North America. Small animal practice. [DOI] 10.1016/j.cvsm.2011.09.006. [PMID] 22285158.
PubMed · Publisher’s Site
2012
Outbreak of equine piroplasmosis in Florida.
Journal of the American Veterinary Medical Association. [DOI] 10.2460/javma.240.5.588. [PMID] 22332629.
PubMed · Publisher’s Site
2010
Evaluation of Canine and Feline Hemograms Using the Idexx Procyte Dx Analyzer Compared To Manual Differential
Journal of Veterinary Internal Medicine.
2009
B-cell lymphoma with Mott cell differentiation in two young adult dogs.
Veterinary clinical pathology. [DOI] 10.1111/j.1939-165X.2008.00101.x. [PMID] 19171017.
PubMed · Publisher’s Site
2009
Hematology of healthy Florida manatees (Trichechus manatus).
Veterinary clinical pathology. [DOI] 10.1111/j.1939-165X.2009.00113.x. [PMID] 19490571.
PubMed · Publisher’s Site
2009
Hemolysis, myopathy, and cardiac disease associated with hereditary phosphofructokinase deficiency in two Whippets.
Veterinary clinical pathology. [DOI] 10.1111/j.1939-165X.2008.00089.x. [PMID] 19228357.
PubMed · Publisher’s Site
2008
Comparison of blood aminotransferase methods for assessment of myopathy and hepatopathy in Florida manatees (Trichechus manatus latirostris).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. [PMID] 18634208.
PubMed
2007
Clinical biochemistry in healthy manatees (Trichechus manatus latirostris).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. [PMID] 17679511.
PubMed
2007
Laboratory findings in acute Cytauxzoon felis infection in cougars (Puma concolor couguar) in Florida.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. [PMID] 17679513.
PubMed
2006
Pathogenesis, laboratory diagnosis, and clinical implications of erythrocyte enzyme deficiencies in dogs, cats, and horses.
Veterinary clinical pathology. [PMID] 16783707.
PubMed
2005
Clinical biochemistry of pregnant and nursing mares.
Veterinary clinical pathology. [PMID] 16134073.
PubMed
2005
Cytologic diagnosis of Lawsonia intracellularis proliferative ileitis in a Japanese snow macaque (Macaca fuscata).
Veterinary clinical pathology. [PMID] 15732020.
PubMed
2003
Intravascular hemolysis associated with liver disease in a horse with marked neutrophil hypersegmentation.
Journal of veterinary internal medicine. [PMID] 12774981.
PubMed
2003
Methemoglobinemia and eccentrocytosis in equine erythrocyte flavin adenine dinucleotide deficiency.
Veterinary pathology. [PMID] 14608016.
PubMed
1999
Hematologic effects of cytauxzoonosis in Florida panthers and Texas cougars in Florida.
Journal of wildlife diseases. [PMID] 10479103.
PubMed
1999
Western immunoblot analysis of the antigens of Haemobartonella felis with sera from experimentally infected cats.
Journal of clinical microbiology. [PMID] 10203508.
PubMed
1996
Congenital erythrocyte enzyme deficiencies.
The Veterinary clinics of North America. Small animal practice. [PMID] 8863387.
PubMed
1996
Cytologic findings in cerebrospinal fluid from two animals with GM2-gangliosisosis.
Veterinary clinical pathology. [PMID] 12660965.
PubMed
1996
Cytologic identification of neural tissue in the cerebrospinal fluid of two dogs.
Veterinary clinical pathology. [PMID] 12660958.
PubMed
1996
Fatal cytauxzoonosis in a captive-reared white tiger (Panthera tigris).
Veterinary pathology. [PMID] 8826011.
PubMed
1994
Equine glucose-6-phosphate dehydrogenase deficiency.
Veterinary pathology. [PMID] 7801429.
PubMed
1994
Hematologic changes associated with serum and hepatic iron alterations in dogs with congenital portosystemic vascular anomalies.
Journal of veterinary internal medicine. [PMID] 8176664.
PubMed
1994
Metabolic and work capacity of skeletal muscle of PFK-deficient dogs studied in situ.
Journal of applied physiology (Bethesda, Md. : 1985). [PMID] 7868469.
PubMed
1994
Methemoglobin reductase deficiency in a cat.
Journal of the American Veterinary Medical Association. [PMID] 7698939.
PubMed
1994
Myelodysplastic syndrome in a quarter horse gelding.
Equine veterinary journal. [PMID] 8143673.
PubMed
1993
Aplastic anemia associated with prolonged high-dose trimethoprim-sulfadiazine administration in two dogs.
Veterinary clinical pathology. [PMID] 12669295.
PubMed
1993
The morphological effects of vincristine sulfate on canine bone marrow cells.
Veterinary clinical pathology. [PMID] 12669276.
PubMed
1992
Characterization of phosphofructokinase-deficient canine erythrocytes.
Journal of inherited metabolic disease. [PMID] 1434514.
PubMed
1992
Developmental changes of 6-phosphofructo-1-kinase subunit levels in erythrocytes from normal dogs and dogs affected by glycogen storage disease type VII.
Comparative biochemistry and physiology. B, Comparative biochemistry. [PMID] 1533828.
PubMed
1992
Seroprevalence of babesiosis in Greyhounds in Florida.
Journal of the American Veterinary Medical Association. [PMID] 1537689.
PubMed
1992
Specialized hematology tests.
Seminars in veterinary medicine and surgery (small animal). [PMID] 1470772.
PubMed
1991
Proposed criteria for classification of acute myeloid leukemia in dogs and cats.
Veterinary clinical pathology. [PMID] 12673541.
PubMed
1990
Polysaccharide storage myopathy in canine phosphofructokinase deficiency (type VII glycogen storage disease).
Veterinary pathology. [PMID] 2137952.
PubMed
1990
Utilization of an enzyme heat stability test and erythrocyte glycolytic intermediate assays to assist in the diagnosis of canine pyruvate kinase deficiency.
Veterinary clinical pathology. [PMID] 12684939.
PubMed
1989
Megakaryblastic leukemia in a dog.
Veterinary clinical pathology. [PMID] 15156514.
PubMed
1989
Postnatal hematologic development in phosphofructokinase-deficient dogs.
Blood. [PMID] 2529931.
PubMed
1988
Babesiosis in a litter of pups.
Journal of the American Veterinary Medical Association. [PMID] 3410795.
PubMed
1988
Effect of 2,3-diphosphoglycerate concentration on the alkaline fragility of phosphofructokinase-deficient canine erythrocytes.
Comparative biochemistry and physiology. B, Comparative biochemistry. [PMID] 2965634.
PubMed
1987
Hemolysis caused by phosphofructokinase deficiency in English springer spaniels: seven cases (1983-1986).
Journal of the American Veterinary Medical Association. [PMID] 2958437.
PubMed
1987
Potential effects of glucocorticoids on serum iron concentration in dogs.
Veterinary clinical pathology. [PMID] 15221702.
PubMed
1987
Prednisone-induced increases in serum alpha-2-globulin and haptoglobin concentrations in dogs.
Veterinary pathology. [PMID] 2435050.
PubMed
1987
Serum ferritin, serum iron, and erythrocyte values in foals.
American journal of veterinary research. [PMID] 3662205.
PubMed
1987
Similarities of two separate cases of feline neoplasia.
Veterinary pathology. [PMID] 3576920.
PubMed
1986
A model for experimental bacterial cystitis in the dog.
Laboratory animal science. [PMID] 3773458.
PubMed
1986
Autosomal recessive inherited phosphofructokinase deficiency in English springer spaniel dogs.
Animal genetics. [PMID] 2940948.
PubMed
1986
Comparison between serum haptoglobin and alpha-2-globulin concentrations in dogs.
Veterinary clinical pathology. [PMID] 15334361.
PubMed
1986
Familial nonspherocytic hemolytic anemia in poodles.
American journal of veterinary research. [PMID] 3963571.
PubMed
1986
Feline large granular lymphoma.
Veterinary pathology. [PMID] 3962087.
PubMed
1986
Hematologic abnormalities associated with chronic acetaminophen administration in a dog.
Journal of the American Veterinary Medical Association. [PMID] 3793579.
PubMed
1985
Characterization of the enzymatic lesion in inherited phosphofructokinase deficiency in the dog: an animal analogue of human glycogen storage disease type VII.
Proceedings of the National Academy of Sciences of the United States of America. [PMID] 2933748.
PubMed
1985
Experimental onion-induced hemolytic anemia in dogs.
Veterinary pathology. [PMID] 4035943.
PubMed
1985
Inherited phosphofructokinase deficiency in dogs with hyperventilation-induced hemolysis: increased in vitro and in vivo alkaline fragility of erythrocytes.
Blood. [PMID] 3155631.
PubMed
1985
Pathologic sideroblasts and siderocytes associated with chloramphenicol therapy in a dog.
Veterinary clinical pathology. [PMID] 15221691.
PubMed
1985
Serum protein reference values in foals during the first year of life: comparison of chemical and electrophoretic methods.
Veterinary clinical pathology. [PMID] 15221688.
PubMed
1985
Ultrastructure of schizonts in the liver of cats with experimentally induced cytauxzoonosis.
American journal of veterinary research. [PMID] 3922259.
PubMed
1985
Ultrastructure of the intraerythrocytic stage of Cytauxzoon felis.
American journal of veterinary research. [PMID] 2988382.
PubMed
1984
Clinical chemistry reference values of foals during the first year of life.
Equine veterinary journal. [PMID] 6479134.
PubMed
1984
Ehrlichiosis in a Florida horse.
Journal of the American Veterinary Medical Association. [PMID] 6469848.
PubMed
1984
Haematology of foals up to one year old.
Equine veterinary journal. [PMID] 6479131.
PubMed
1982
Myeloproliferative disease with megakaryocytic predominance in a dog with occult dirofilariasis.
Veterinary clinical pathology. [PMID] 15311376.
PubMed
1981
Myeloproliferative disorders in dogs and cats.
The Veterinary clinics of North America. Small animal practice. [PMID] 7032050.
PubMed
1981
Well-differentiated lymphocytic leukemia in a dog: long-term survival without therapy.
Veterinary pathology. [PMID] 7467071.
PubMed
1980
Canine hemolytic anemias.
Journal of the American Veterinary Medical Association. [PMID] 7380717.
PubMed
1980
Noncrystalline inclusions in erythrocytes of a rhinoceros iguana.
Veterinary clinical pathology. [PMID] 15314774.
PubMed
1979
Benzocaine-induced methemoglobinemia in dogs.
Journal of the American Veterinary Medical Association. [PMID] 511741.
PubMed
1979
Ehrlichiosis in wolves, dogs, and wolf-dog crosses.
Journal of the American Veterinary Medical Association. [PMID] 521367.
PubMed
1978
Cyclic thrombocytopenia induced by a Rickettsia-like agent in dogs.
The Journal of infectious diseases. [PMID] 627738.
PubMed
1978
Feline haptoglobin.
American journal of veterinary research. [PMID] 646191.
PubMed
1978
Feline myeloproliferative disease. Changing manifestations in the peripheral blood.
Veterinary pathology. [PMID] 695218.
PubMed
1978
Ultrastructure of erythrocytes parasitized by Haemobartonella felis.
The Journal of parasitology. [PMID] 207847.
PubMed
1977
Erythrocyte pyruvate kinase deficiency in a beagle dog.
Veterinary clinical pathology. [PMID] 15314790.
PubMed
1976
Phenazopyridine toxicosis in the cat.
Journal of the American Veterinary Medical Association. [PMID] 956020.
PubMed
1975
Erythrocyte enzyme activities and glutathione levels of the horse, cat, dog and man.
Comparative biochemistry and physiology. B, Comparative biochemistry. [PMID] 128434.
PubMed
1975
Mammalian erythrocyte glutathione reductase: kinetic constants and saturation with cofactor.
American journal of veterinary research. [PMID] 242245.
PubMed
1974
Methemoglobin reductase deficiency in a dog.
Journal of the American Veterinary Medical Association. [PMID] 4151105.
PubMed

Contact Details

Phones:
Business:
(352) 294-4277
Emails:
Business:
jwharvey@ufl.edu
Addresses:
Business Mailing:
PO Box 100103
 GAINESVILLE FL 32610
Business Street:
BUILDING 215
COLLEGE OF VETERINARY MEDICINE
VS-2B
 GAINESVILLE FL 32608