Klibs Galvão, Med.Vet., MVPM, PhD, DACT, DACVPM
Associate Chair & Professor
Department:
Large Animal Clinical Sciences
Business Phone:
(352) 294-4788
Business Email:
galvaok@ufl.edu
Accomplishments
Florida Veterinary Medical Associtation Clinical Investigator Award
2021
·
University of Florida, College of Veterinary Medicine
Term Professorship Award
2020
·
University of Florida
Term Professorship Award
2017
·
University of Florida
C.E. Cornelius Young Investigator Award
2015
·
University of Florida, College of Veterinary Medicine
Excellence Award for Assistant Professors
2013
·
University of Florida
Teaching Profile
Courses Taught
2011-2023
VEM5835 Food Animal Repro Med
2010-2023
VEM5735 Food Anml/Repro Med
2019-2020
VEM5352 Dairy Production Med
2011-2023
VEM5277 Adv Bovine Reproduct
2011-2012,2014-2020,2019-2023
VEM5111 Animal Systems 2
2012-2018,2020-2023
VEM5836 Adv Clk Rural Anim Md
2011-2016,2018-2023
VEM5278L Theriogenology
2015,2018-2022,2022-2023
VME6905 Problems in Veterinary Medical Sciences
2018
VME7979 Advanced Research
2011-2014
VME4103 Livestock Health/Disease Prevention
2013
VEM5761 Core Clk Anesthesiol
2021
ANS6905 Problems in Animal Science
Board Certifications
-
TheriogenologyAmerican College of Theriogenologists
-
Veterinary Preventive MedicineAmerican College of Veterinary Preventive Medicine
Research Profile
My long term research goals are to improve the health of dairy cattle and to improve the sustainability of the dairy enterprise. — Uterine microbiology and immunology in health and disease
— Epidemiological investigation of the risk factors for uterine diseases
— Development and evaluation of therapies for prevention and treatment of uterine diseases
— The use of herd simulation models and budget impact analysis to understand how uterine disease and impaired fertility affect the profitability of dairy herds.
Currently, I am investigating the origin of the uterine microbiome and the intersection between the uterine microbiome, metabolome, and the immune system in dairy cows with the goal of understanding the etiology of uterine diseases.
Open Researcher and Contributor ID (ORCID)
0000-0002-6683-4476
Publications
2023
Blood metabolomics and impacted cellular mechanisms during transition into lactation in dairy cows that develop metritis
Journal of Dairy Science.
[DOI] 10.3168/jds.2023-23433.
2023
Combined effect of purulent vaginal discharge and anovulation on pregnancy status in a large multi-state population of Holstein cows
JDS Communications.
4(2):106-110
[DOI] 10.3168/jdsc.2022-0271.
[PMID] 36974209.
2023
Establishing Galleria mellonella as an invertebrate model for the emerging multi-host pathogen Helcococcus ovis
Virulence.
14(1)
[DOI] 10.1080/21505594.2023.2186377.
[PMID] 36862000.
2023
Unraveling the immune and metabolic changes associated with metritis in dairy cows
Journal of Dairy Science.
[DOI] 10.3168/jds.2023-23289.
2022
Behavioral changes of metritic primiparous cows treated with chitosan microparticles or ceftiofur
JDS Communications.
3(4):265-269
[DOI] 10.3168/jdsc.2022-0221.
[PMID] 36338013.
2022
Tracing the source and route of uterine colonization by exploring the genetic relationship of Escherichia coli isolated from the reproductive and gastrointestinal tract of dairy cows
Veterinary Microbiology.
266
[DOI] 10.1016/j.vetmic.2022.109355.
2021
Associations between dry period length and time to culling and pregnancy in the subsequent lactation
Journal of Dairy Science.
104(8):8885-8900
[DOI] 10.3168/jds.2021-20119.
2021
Effect of body condition change and health status during early lactation on performance and survival of Holstein cows
Journal of Dairy Science.
104(12):12785-12799
[DOI] 10.3168/jds.2020-20091.
2021
Effects of adding an automated monitoring device to the health screening of postpartum Holstein cows on survival and productive and reproductive performances
Journal of Dairy Science.
104(3):3439-3457
[DOI] 10.3168/jds.2020-18562.
2021
Failure of clinical cure in dairy cows treated for metritis is associated with reduced productive and reproductive performance
Journal of Dairy Science.
104(6):7056-7070
[DOI] 10.3168/jds.2020-19661.
2021
Integration of statistical inferences and machine learning algorithms for prediction of metritis cure in dairy cows
Journal of Dairy Science.
104(12):12887-12899
[DOI] 10.3168/jds.2021-20262.
2021
Molecular characterization of carbapenem-resistant and virulent plasmids in Klebsiella pneumoniae from patients with bloodstream infections in China.
Emerging microbes & infections.
10(1):700-709
[DOI] 10.1080/22221751.2021.1906163.
[PMID] 33739229.
2020
Associations of reproductive indices with fertility outcomes, milk yield, and survival in Holstein cows
Journal of Dairy Science.
103(7):6647-6660
[DOI] 10.3168/jds.2019-17867.
2020
Combined effect of mastitis and parity on pregnancy loss in lactating Holstein cows
Theriogenology.
143:57-63
[DOI] 10.1016/j.theriogenology.2019.12.002.
2020
Early-lactation diseases and fertility in 2 seasons of calving across US dairy herds
Journal of Dairy Science.
103(11):10560-10576
[DOI] 10.3168/jds.2019-17951.
2020
Effect of Chitosan Microparticles on the Uterine Microbiome of Dairy Cows with Metritis
Applied and Environmental Microbiology.
86(18)
[DOI] 10.1128/aem.01066-20.
2020
Genome-enable prediction for health traits using high-density SNP panel in US Holstein cattle.
Animal genetics.
51(2):192-199
[DOI] 10.1111/age.12892.
[PMID] 31909828.
2020
Using chitosan microparticles to treat metritis in lactating dairy cows
Journal of Dairy Science.
103(8):7377-7391
[DOI] 10.3168/jds.2019-18028.
2019
Draft Genome Sequences of Bacteroides pyogenes Strains Isolated from the Uterus of Holstein Dairy Cows with Metritis
Microbiology resource announcements.
8(41)
[DOI] 10.1128/MRA.01043-19.
2019
Draft Genome Sequences of Helcococcus ovis Strains Isolated at Time of Metritis Diagnosis from the Uterus of Holstein Dairy Cows
Microbiology resource announcements.
8(22)
[DOI] 10.1128/MRA.00402-19.
2019
Draft Genome Sequences of Two Fusobacterium necrophorum Strains Isolated from the Uterus of Dairy Cows with Metritis
Microbiology resource announcements.
8(17)
[DOI] 10.1128/MRA.00201-19.
2019
Genomic Diversity, Virulence, and Antimicrobial Resistance of Klebsiella pneumoniae Strains from Cows and Humans.
Applied and environmental microbiology.
85(6)
[DOI] 10.1128/AEM.02654-18.
[PMID] 30610074.
2019
Symposium review: The uterine microbiome associated with the development of uterine disease in dairy cows
Journal of Dairy Science.
102(12):11786-11797
[DOI] 10.3168/jds.2019-17106.
2018
An Advanced Understanding of Uterine Microbial Ecology Associated with Metritis in Dairy Cows
Genomics & Informatics.
16(4)
[DOI] 10.5808/gi.2018.16.4.e21.
2018
Epidemiologic and economic analyses of pregnancy loss attributable to mastitis in primiparous Holstein cows.
Journal of dairy science.
101(11):10142-10150
[DOI] 10.3168/jds.2018-14619.
[PMID] 30146277.
2018
Gene Mapping and Gene-Set Analysis for Milk Fever Incidence in Holstein Dairy Cattle.
Frontiers in genetics.
9
[DOI] 10.3389/fgene.2018.00465.
[PMID] 30364193.
2018
Quantifying Known and Emerging Uterine Pathogens, and Evaluating Their Association With Metritis and Fever in Dairy Cows
Theriogenology.
114:25-33
[DOI] 10.1016/j.theriogenology.2018.03.016.
2018
Shift of Uterine Microbiota Associated With Antibiotic Treatment and Cure of Metritis in Dairy Cows
Veterinary Microbiology.
214:132-139
[DOI] 10.1016/j.vetmic.2017.12.022.
2017
Blood as a route of transmission of uterine pathogens from the gut to the uterus in cows
Microbiome.
5(1)
[DOI] 10.1186/s40168-017-0328-9.
[PMID] 28841911.
2017
Effects of Intrauterine Infusion of Escherichia Coli Lipopolysaccharide on Uterine Mrna Gene Expression and Peripheral Polymorphonuclear Leukocytes in Jersey Cows Diagnosed With Purulent Vaginal Discharge
Journal of Dairy Science.
100(6):4784-4796
[DOI] 10.3168/jds.2016-11643.
2017
Evidence that mastitis can cause pregnancy loss in dairy cows: A systematic review of observational studies.
Journal of dairy science.
100(10):8322-8329
[DOI] 10.3168/jds.2017-12711.
[PMID] 28780088.
2017
Using Doppler Ultrasonography on Day 34 of Pregnancy to Predict Pregnancy Loss in Lactating Dairy Cattle
Journal of Dairy Science.
100(4):3266-3271
[DOI] 10.3168/jds.2016-11955.
2016
Chitosan Microparticles Exert Broad-Spectrum Antimicrobial Activity against Antibiotic-Resistant Micro-organisms without Increasing Resistance.
ACS applied materials & interfaces.
8(17):10700-9
[DOI] 10.1021/acsami.6b00894.
[PMID] 27057922.
2016
Clinical Response After Chitosan Microparticle Administration and Preliminary Assessment of Efficacy in Preventing Metritis in Lactating Dairy Cows
Journal of Dairy Science.
99(11):8946-8955
[DOI] 10.3168/jds.2016-11400.
2016
Combined use of progesterone inserts, ultrasongraphy, and GnRH to identify and resynchronize nonpregnant cows and heifers 21 days after timed artificial insemination
Theriogenology.
85(2):230-237
[DOI] 10.1016/j.theriogenology.2015.09.052.
2016
Draft Genome Sequence of an Escherichia coli O8:H19 Sequence Type 708 Strain Isolated from a Holstein Dairy Cow with Metritis.
Genome announcements.
4(2)
[DOI] 10.1128/genomeA.00261-16.
[PMID] 27056235.
2016
Effects of Oral Calcium Supplementation on Mineral and Acid-Base Status, Energy Metabolites, and Health of Postpartum Dairy Cows
Journal of Dairy Science.
99(10):8397-8416
[DOI] 10.3168/jds.2015-10527.
2016
Effects of Oral Calcium Supplementation on Productive and Reproductive Performance in Holstein Cows
Journal of Dairy Science.
99(10):8417-8430
[DOI] 10.3168/jds.2015-10529.
2016
Factors Affecting the Success of a Large Embryo Transfer Program in Holstein Cattle in a Commercial Herd in the Southeast Region of the United States
Theriogenology.
86(7):1834-1841
[DOI] 10.1016/j.theriogenology.2016.05.032.
2016
Uterine Microbiota and Immune Parameters Associated with Fever in Dairy Cows with Metritis
PLOS ONE.
11(11)
[DOI] 10.1371/journal.pone.0165740.
[PMID] 27802303.
2016
Vulvovaginal laceration as a risk factor for uterine disease in postpartum dairy cows.
Journal of dairy science.
99(6):4629-4637
[DOI] 10.3168/jds.2016-10872.
[PMID] 27016827.
2015
Effect of oral mineral and energy supplementation on blood mineral concentrations, energetic and inflammatory profile, and milk yield in dairy cows affected with dystocia.
Veterinary journal (London, England : 1997).
204(2):186-91
[DOI] 10.1016/j.tvjl.2015.03.001.
[PMID] 25900193.
2015
Effects of intrauterine infusion of Trueperella pyogenes on endometrial mRNA expression of proinflammatory cytokines and luteolytic cascade genes and their association with luteal life span in dairy cows
Theriogenology.
84(8):1263-1272
[DOI] 10.1016/j.theriogenology.2015.07.004.
2015
Factors associated with early cyclicity in postpartum dairy cows.
Journal of dairy science.
98(1):229-39
[DOI] 10.3168/jds.2014-8460.
[PMID] 25465552.
2015
Uterine Microbiota Progression from Calving until Establishment of Metritis in Dairy Cows.
Applied and environmental microbiology.
81(18):6324-32
[DOI] 10.1128/AEM.01753-15.
[PMID] 26150453.
2014
Efficacy of ampicillin trihydrate or ceftiofur hydrochloride for treatment of metritis and subsequent fertility in dairy cows.
Journal of dairy science.
97(9):5401-14
[DOI] 10.3168/jds.2013-7569.
[PMID] 24952780.
2014
Individual and combined effects of anovulation and cytological endometritis on the reproductive performance of dairy cows.
Journal of dairy science.
97(9):5415-25
[DOI] 10.3168/jds.2013-7725.
[PMID] 24996269.
2014
Inducing ovulation early postpartum influences uterine health and fertility in dairy cows.
Journal of dairy science.
97(6):3558-69
[DOI] 10.3168/jds.2013-7533.
[PMID] 24704233.
2013
Economic comparison of reproductive programs for dairy herds using estrus detection, timed artificial insemination, or a combination.
Journal of dairy science.
96(4):2681-2693
[DOI] 10.3168/jds.2012-5982.
[PMID] 23415521.
2013
Effect of feeding maternal colostrum or plasma-derived or colostrum-derived colostrum replacer on passive transfer of immunity, health, and performance of preweaning heifer calves.
Journal of dairy science.
96(5):3247-56
[DOI] 10.3168/jds.2012-6339.
[PMID] 23497992.
2013
Effects of 1 or 2 treatments with prostaglandin F₂α on subclinical endometritis and fertility in lactating dairy cows inseminated by timed artificial insemination.
Journal of dairy science.
96(10):6480-8
[DOI] 10.3168/jds.2013-6850.
[PMID] 23910554.
2013
Innate immune gene variation and differential susceptibility to uterine diseases in Holstein cows.
Theriogenology.
80(4):384-90
[DOI] 10.1016/j.theriogenology.2013.04.027.
[PMID] 23768650.
2013
Timed artificial insemination early in the breeding season improves the reproductive performance of suckled beef cows.
Theriogenology.
79(4):625-32
[DOI] 10.1016/j.theriogenology.2012.11.016.
[PMID] 23261306.
2012
Effect of one or three timed artificial inseminations before natural service on reproductive performance of lactating dairy cows not observed for detection of estrus.
Theriogenology.
77(9):1918-27
[DOI] 10.1016/j.theriogenology.2012.01.011.
[PMID] 22444549.
2012
Effects of diagnostic low-volume uterine lavage shortly before first service on reproductive performance, culling and milk production.
Theriogenology.
77(6):1217-22
[DOI] 10.1016/j.theriogenology.2011.10.029.
[PMID] 22192391.
2012
Effects of Prostaglandin F2 Alpha On Subclinical Endometritis and Fertility of Lactating Dairy Cows Subjected To Timed Ai
Reproduction in Domestic Animals.
47
2012
Evaluation of cytokine expression by blood monocytes of lactating Holstein cows with or without postpartum uterine disease.
Theriogenology.
77(2):356-72
[DOI] 10.1016/j.theriogenology.2011.08.008.
[PMID] 21924475.
2012
Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease.
Journal of dairy science.
95(12):7158-72
[DOI] 10.3168/jds.2012-5812.
[PMID] 23021755.
2010
Factors affecting synchronization and conception rate after the Ovsynch protocol in lactating Holstein cows.
Reproduction in domestic animals = Zuchthygiene.
45(3):439-46
[DOI] 10.1111/j.1439-0531.2008.01220.x.
[PMID] 19144008.
2010
Supplementation with calcium salts of linoleic and trans-octadecenoic acids improves fertility of lactating dairy cows.
Reproduction in domestic animals = Zuchthygiene.
45(1):55-62
[DOI] 10.1111/j.1439-0531.2008.01237.x.
[PMID] 19144007.
2009
Effect of fat source differing in fatty acid profile on metabolic parameters, fertilization, and embryo quality in high-producing dairy cows.
Journal of dairy science.
92(4):1520-31
[DOI] 10.3168/jds.2008-1614.
[PMID] 19307633.
2009
Effect of intrauterine infusion of ceftiofur on uterine health and fertility in dairy cows.
Journal of dairy science.
92(4):1532-42
[DOI] 10.3168/jds.2008-1615.
[PMID] 19307634.
2008
Effect of Calcium Salts of Fish and Palm Oils On Lactational Performance of Holstein Cows
Animal Feed Science and Technology.
140(1-2):18-38
[DOI] 10.1016/j.anifeedsci.2007.01.018.
2008
Gossypol disrupts embryo development in heifers.
Journal of dairy science.
91(8):3015-24
[DOI] 10.3168/jds.2007-0939.
[PMID] 18650278.
Grants
Sep 2021
ACTIVE
The origin and progression of the uterine microbiome in cattle
Role: Principal Investigator
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Jul 2021
ACTIVE
Control of bovine bacterial metritis through investigation of polymicrobial interactions and the effect of bacterial products on host cells
Role: Co-Investigator
Funding: LONG ISLAND UNIV
via US DEPT OF AG NATL INST OF FOOD AND AG
Jan 2021
ACTIVE
Reproductive Biotechnology Concentration at University of Florida
Role: Faculty
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Sep 2019
– Aug 2023
Predicting Metritis Cure as a Path to Reduce Antimicrobial Use in Dairy Cows
Role: Principal Investigator
Funding: TEXAS TECH UNIV
via US DEPT OF AG NATL INST OF FOOD AND AG
Aug 2019
ACTIVE
A metabolomic approach to determining factors that modulate host immunity and uterine microbiota
Role: Principal Investigator
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Aug 2019
ACTIVE
Development of nano-antimicrobials with beta-lactamase inhibitor to treat infections caused by multi-drug resistant bacteria
Role: Co-Project Director/Principal Investigator
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Dec 2016
– May 2018
Testing the Effect of Thermocal oral calcium capsules supplementation on blood calcium pattern in early lactation dairy cows
Role: Principal Investigator
Funding: VAN BEEK NATURAL SCIENCE
Mar 2016
– Feb 2021
Using chitosan microparticles to treat metritis in lactating dairy cows
Role: Principal Investigator
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Feb 2016
– Jul 2019
Genomic Selection for Improved Fertility of Dairy Cows with Emphases on Cyclicity and Pregnancy
Role: Project Manager
Funding: COLORADO STATE UNIV
via US DEPT OF AG NATL INST OF FOOD AND AG
Dec 2014
– Nov 2017
Comparison of Cloprostenol Sodium and Dinoprost Tromethamine: Interval to estrus, estrus intensity and duration, and fertility
Role: Principal Investigator
Funding: MERCK ANIMAL HEALTH
Jan 2014
– Dec 2018
Development of chitosan nanoparticles targeting pathogenic Escherichia coli in beef and dairy
Role: Project Manager
Funding: US DEPT OF AG NATL INST OF FOOD AND AG
Education
Doctor of Philosophy in Comparative Biomedical Sciences
2009
·
School of Veterinary Medicine, Cornell University
Residency in Dairy Production Medicine
2006
·
School of Veterinary Medicine, University of California, Davis
Master of Preventive Veterinary Medicine
2005
·
School of Veterinary Medicine, University of California, Davis
Medico Veterinario
2002
·
School of Veterinary Medicine, Federal University of Goiás
Contact Details
Phones:
- Business:
- (352) 294-4788
Emails:
- Business:
- galvaok@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100136
GAINESVILLE FL 32610 - Business Street:
-
119 DERISO HALL
2015 SW 16 AVE.
GAINESVILLE FL 32608