Marília Takada

Marília Takada,

Assistant Professor, Radiation Oncology Service Chief

Department: Small Animal Clinical Sciences
Business Phone: (352) 392-2235
Business Email: mtakada@ufl.edu

Accomplishments

E. Gregory MacEwen Memorial Award
2022 · Veterinary Cancer Society
Young Investigator Award – National Veterinary Scholar's Symposium
2018 · AVMA/AVMF
International Training Scholarship at University of Tokyo
2009 · Japan International Cooperation Agency

Teaching Profile

Courses Taught
2021-2024
VEM5872C Veterinary Medical & Radiation Oncology Clerkship
2022-2024
VEM5181 Radiol Tech W/Lab
2022-2024
VEM5308 Vet Med Oncology

Board Certifications

  • Diplomate in Radiation Oncology
    American College of Veterinary Radiology

Research Profile

Research interests include the investigation of: – Hypofractionated radiation protocols, and the combination of radiation with targeted therapeutic agents. – Trametinib as a novel targeted drug for canine histiocytic sarcoma. – Oncogenic drivers of canine histiocytic sarcoma, and development of biomarkers for early detection/treatment response.

Open Researcher and Contributor ID (ORCID)

0000-0001-9509-0528

Publications

2022
Identification of a Hypomorphic FANCG Variant in Bernese Mountain Dogs
Genes. 13(10) [DOI] 10.3390/genes13101693. [PMID] 36292578.
2020
Definitive-intent radiotherapy for sinonasal carcinoma in cats: A multicenter retrospective assessment.
Veterinary and comparative oncology. 18(4):626-633 [DOI] 10.1111/vco.12583.
2019
Activating Mutations in PTPN11 and KRAS in Canine Histiocytic Sarcomas.
Genes. 10(7) [DOI] 10.3390/genes10070505. [PMID] 31277422.
2019
Development of an Orthotopic Intrasplenic Xenograft Mouse Model of Canine Histiocytic Sarcoma and Its Use in Evaluating the Efficacy of Treatment with Dasatinib.
Comparative medicine. 69(1):22-28 [DOI] 10.30802/AALAS-CM-18-000065. [PMID] 30717820.
2019
Dynamic Contrast-Enhanced MRI of OATP Dysfunction in Diabetes.
Diabetes. 68(2):271-280 [DOI] 10.2337/db18-0525. [PMID] 30487262.
2018
A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies.
BMC cancer. 18(1) [DOI] 10.1186/s12885-018-4132-0. [PMID] 29490634.
2018
Gain-of-function mutation in PTPN11 in histiocytic sarcomas of Bernese Mountain Dogs.
Veterinary and comparative oncology. 16(2):220-228 [DOI] 10.1111/vco.12357. [PMID] 28929581.
2018
Investigation of novel chemotherapeutics for feline oral squamous cell carcinoma.
Oncotarget. 9(69):33098-33109 [DOI] 10.18632/oncotarget.26006. [PMID] 30237854.
2018
Targeting MEK in a Translational Model of Histiocytic Sarcoma.
Molecular cancer therapeutics. 17(11):2439-2450 [DOI] 10.1158/1535-7163.MCT-17-1273. [PMID] 30135215.
2016
Prostate cancer characterization by optical contrast enhanced photoacoustics.
Proceedings of SPIE–the International Society for Optical Engineering. 9708 [DOI] 10.1117/12.2213064. [PMID] 28529403.

Grants

Jun 2022 – Feb 2024
A multicenter, randomized, double-blind, placebo-controlled, pilot clinical study comparing primary radiotherapy with radiotherapy combined with MT0321 intravenous administration for canine intranasal adenocarcinoma
Role: Principal Investigator
Funding: MALIGNANT TUMOR TREATMENT TECHNOLOGIES
May 2022 – Apr 2023
Feasibility of radiotherapy combined with MT0321 intravenous administration for canine intranasal adenocarcinoma
Role: Co-Investigator
Funding: MALIGNANT TUMOR TREATMENT TECHNOLOGIES
Mar 2022 ACTIVE
Mechanism of LSD1 Function and Its Therapeutic Application for Progressive Oral Malignancy
Role: Co-Project Director/Principal Investigator
Funding: BOSTON UNIV via NATL INST OF HLTH NIDCR

Education

Residency in Radiation Oncology
2021 · University of Wisconsin – Madison
PhD in Comparative Medicine and Integrative Biology
2018 · Michigan State University
MSc in Comparative Medicine and Integrative Biology
2013 · Michigan State University
Residency in Small Animal Surgery
2008 · Anhembi Morumbi University (Brazil)
Doctor of Veterinary Medicine
2005 · University of Sao Paulo (Brazil)

Contact Details

Phones:
Business:
(352) 392-2235
Emails:
Business:
mtakada@ufl.edu
Addresses:
Business Mailing:
PO Box 100116
GAINESVILLE FL 32610