Keijiro Shiomitsu

Keijiro Shiomitsu,

Associate Professor, Radiation Oncology Service Chief

Department: Small Animal Clinical Sciences
Business Phone: (352) 392-2235
Business Email: kshiomitsu@ufl.edu

Research Profile

— Angiogenesis

— Radiation sensitizer

— Intensity Modulated Radiation Therapy (IMRT)

Publications

2021
C-kit, flt-3, PDGFR-β, and VEGFR2 expression in canine adrenal tumors and correlation with outcome following adrenalectomy.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 85(4):279-284 [PMID] 34602732.
View on: PubMed
2021
Evaluation of ponatinib in vitro effect in three canine mast cell tumor cell lines expressing FGFR-1, PDGFR-α, and VEGFR-2.
Veterinary journal (London, England : 1997). 269 [DOI] 10.1016/j.tvjl.2021.105621. [PMID] 33593493.
2021
Novel application of single-cell next-generation sequencing for determination of intratumoral heterogeneity of canine osteosarcoma cell lines
Journal of Veterinary Diagnostic Investigation. 33(2):1040638720985242-278 [DOI] 10.1177/1040638720985242. [PMID] 33446089.
2020
Molecular diagnosis using RNAscope in-situ hybridization in canine malignancies.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 84(4):319-323 [PMID] 33012982.
View on: PubMed
2020
Multimodality treatment including ONCEPT for canine oral melanoma: A retrospective analysis of 131 dogs.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 61(4):471-480 [DOI] 10.1111/vru.12860. [PMID] 32323424.
2020
Outcome of intensity-modulated radiation therapy-based stereotactic radiation therapy for treatment of canine nasal carcinomas.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 61(3):370-378 [DOI] 10.1111/vru.12854. [PMID] 32189433.
2019
Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses.
Viruses. 11(2) [DOI] 10.3390/v11020136. [PMID] 30717485.
2019
In vitro effects of the chemotherapy agent water-soluble micellar paclitaxel (Paccal Vet) on canine hemangiosarcoma cell lines.
Veterinary and comparative oncology. 17(1):32-41 [DOI] 10.1111/vco.12442. [PMID] 30267450.
2016
Comparison of Calculated Radiation Delivery Versus Actual Radiation Delivery in Military Macaws (Ara militaris).
Journal of avian medicine and surgery. 30(1):1-7 [DOI] 10.1647/2014-062. [PMID] 27088738.
2015
Evaluation of a ferret-specific formula for determining body surface area to improve chemotherapeutic dosing.
American journal of veterinary research. 76(2):142-8 [DOI] 10.2460/ajvr.76.2.142. [PMID] 25629911.
2015
Prognostic value of baseline absolute lymphocyte concentration and neutrophil/lymphocyte ratio in dogs with newly diagnosed multi-centric lymphoma.
Veterinary and comparative oncology. 13(4):337-47 [DOI] 10.1111/vco.12045. [PMID] 23786518.
2013
Reirradiation of canine nasal carcinomas treated with coarsely fractionated radiation protocols: 37 cases.
Journal of the American Animal Hospital Association. 49(5):318-24 [DOI] 10.5326/JAAHA-MS-5920. [PMID] 23861260.
2013
What is your diagnosis? Abdominal fluid from a dog.
Veterinary clinical pathology. 42(1):113-4 [DOI] 10.1111/j.1939-165X.2012.00479.x. [PMID] 23083469.
2012
Cutaneous epitheliotropic lymphoma with dual CD3 and c-kit expression in a dog.
Veterinary clinical pathology. 41(4):594-8 [DOI] 10.1111/j.1939-165x.2012.00477.x. [PMID] 23083432.
2010
Bleomycin/interleukin-12 electrochemogene therapy for treating naturally occurring spontaneous neoplasms in dogs.
Cancer gene therapy. 17(7):457-64 [DOI] 10.1038/cgt.2010.6. [PMID] 20150931.
2010
Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs.
Cancer gene therapy. 17(8):571-8 [DOI] 10.1038/cgt.2010.13. [PMID] 20414325.
2010
Clinical outcome in dogs with nasal tumors treated with intensity-modulated radiation therapy.
The Canadian veterinary journal = La revue veterinaire canadienne. 51(3):293-300 [PMID] 20514254.
View on: PubMed
2009
Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumours.
Veterinary and comparative oncology. 7(2):106-14 [DOI] 10.1111/j.1476-5829.2009.00178.x. [PMID] 19453364.
2008
Intratumoral bleomycin and IL-12 electrochemogenetherapy for treating head and neck tumors in dogs.
Methods in molecular biology (Clifton, N.J.). 423:319-25 [DOI] 10.1007/978-1-59745-194-9_24. [PMID] 18370210.
2008
Radiosensitivity of canine osteosarcoma cells transfected with wild-type p53 in vitro.
Veterinary and comparative oncology. 6(3):193-200 [DOI] 10.1111/j.1476-5829.2008.00160.x. [PMID] 19178679.
1973
[Evaluation of nursing of home patients with special reference to medication].
[Hokenfu zasshi] The Japanese journal for public health nurse. 29(10):784-9 [PMID] 4491180.
View on: PubMed

Grants

Jul 2020 ACTIVE
Characterization of Expression and Prognostic Implications of GD2S and GD3S in Canine Histiocytic Sarcoma
Role: Co-Investigator
Funding: VETERINARY CANCER SOCIETY
Jun 2019 – Sep 2021
Evaluation of novel colchicine binding site inhibitors, VERU-111, on canine malignancies in vitro
Role: Principal Investigator
Funding: VERU
Apr 2019 – Dec 2020
Development of RNA in-situ hybridization (RNAscope) to identify T regulatory cells and their function within the tumor microenvironment of canine oral malignant melanoma.
Role: Co-Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Jun 2016 – Sep 2016
D16CA-617: In Vitro Effects of the Chemotherapeutic Agent Water-Soluble Paclitaxel on Canine Mast Cell Tumor Cell Lines
Role: Principal Investigator
Funding: MORRIS ANIMAL FOU

Education

Residency
2008 · North Carolina State University
Bachelor in Veterinary Science
1997 · Azabu University

Teaching Profile

Courses Taught
2020-2021
VEM5872C Veterinary Medical & Radiation Oncology Clerkship
2015-2021
VEM5308 Vet Med Oncology
2015-2020
VEM5873 Oncology Clrkshp Elec
2017-2019
VEM5181 Radiol Tech W/Lab

Contact Details

Phones:
Business:
(352) 392-2235
Emails:
Business:
kshiomitsu@ufl.edu