Domenico Santoro

Domenico Santoro,

Associate Professor, Dermatology

Department: Small Animal Clinical Sciences
Business Phone: (352) 392-2235
Business Email: dsantoro@ufl.edu

Accomplishments

Elective Small Animal Clinician of the Year
2021 · Veterinary students – Class of 2021
Brasley Fellowship Award
2010-2013 · University of Illinois
Best clinical research presentation
2010 · Phi Zeta Research day

Board Certifications

  • Veterinary Clinical Microbiology and Immunology
    American College of Veterinary Microbiologists (bacteriology/mycology & immunology)
  • Veterinary Dermatology
    European College of Veterinary Dermatology
  • Veterinary Dermatology
    American College of Veterinary Dermatology

Research Profile

Skin barrier defects in the pathogenesis of atopic dermatitis, alternative treatments for atopic dermatitis, immunology, pathogenesis and treatment of canine leishmaniosis.

Open Researcher and Contributor ID (ORCID)

0000-0002-4893-4289

Areas of Interest
  • Clinical Microbiology
  • Environmental allergies
  • Host-pathogen interaction
  • Innate immunity

Publications

2021
A clinical retrospective study of Caparinia tripilis (Psoroptidae) mite dermatitis in pet African pygmy hedgehogs (Ateletrix albiventris) in southern Italy.
Veterinary dermatology. [DOI] 10.1111/vde.12991. [PMID] 34180083.
2021
Clinical efficacy of spray-based heat-treated lactobacilli in canine atopic dermatitis: a preliminary, open-label, uncontrolled study.
Veterinary dermatology. 32(2):114-e23 [DOI] 10.1111/vde.12915. [PMID] 33245188.
2021
Clinical signs and diagnosis of feline atopic syndrome: detailed guidelines for a correct diagnosis.
Veterinary dermatology. 32(1):26-e6 [DOI] 10.1111/vde.12935. [PMID] 33470017.
2021
Efficacy of Fluralaner in the Treatment of Sarcoptic Mange (Sarcoptes scabiei) in 12 Pet Rabbits.
Topics in companion animal medicine. 43 [DOI] 10.1016/j.tcam.2021.100528. [PMID] 33548547.
2021
Evaluation of the cutaneous expression of IL-17, IL-22, IL-31, and their receptors in canine atopic dermatitis.
Research in veterinary science. 136:74-80 [DOI] 10.1016/j.rvsc.2020.12.015. [PMID] 33588097.
2021
Evaluation of the cutaneous inflammatory cells in dogs with leishmaniosis and in dogs without the disease that were naturally infected by Leishmania infantum (syn. L. chagasi).
Veterinary dermatology. 32(2):99-e19 [DOI] 10.1111/vde.12922.
2021
Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug-resistant clinical isolates of Staphylococcus pseudintermedius.
Veterinary dermatology. [DOI] 10.1111/vde.13018. [PMID] 34490674.
2021
Feline allergic diseases: introduction and proposed nomenclature.
Veterinary dermatology. 32(1):8-e2 [DOI] 10.1111/vde.12899. [PMID] 33470016.
2021
Intradermal immunotherapy with actinomycetales preparations as treatment for feline atopic syndrome: a randomized, placebo-controlled, double-blinded study.
Veterinary dermatology. [DOI] 10.1111/vde.12946. [PMID] 33890342.
2021
The Use of Adaptive Learning Technology to Enhance Learning in Clinical Veterinary Dermatology.
Journal of veterinary medical education. [DOI] 10.3138/jvme-2020-0069. [PMID] 33929938.
2020
Expression of Serum Exosomal miRNA 122 and Lipoprotein Levels in Dogs Naturally Infected by Leishmania infantum: A Preliminary Study.
Animals : an open access journal from MDPI. 10(1) [DOI] 10.3390/ani10010100. [PMID] 31936232.
2020
Identification of differentially expressed microRNAs in the skin of experimentally sensitized naturally affected atopic beagles by next-generation sequencing.
Immunogenetics. 72(4):241-250 [DOI] 10.1007/s00251-020-01162-w. [PMID] 32219493.
2020
Noninvasive evaluation of vascular endothelial growth factor-A (VEGF-A) protein concentrations in the stratum corneum and serum of healthy and atopic dogs.
Veterinary dermatology. 31(2):102-105 [DOI] 10.1111/vde.12798.
2020
Orchard grass allergy in an African spur-thighed tortoise (Centrochelys sulcata) confirmed via intradermal allergen testing and provocation testing.
Veterinary dermatology. 31(6):491-e129 [DOI] 10.1111/vde.12889. [PMID] 32929832.
2020
Subcutaneous nodules and dermatitis associated with non-immitis non-repens dirofilariosis morphologically consistent with Dirofilaria striata in a 2-year-old male domestic cat in Florida, USA.
The veterinary quarterly. 40(1):215-222 [DOI] 10.1080/01652176.2020.1814972. [PMID] 32838703.
2019
A defective release of host defense peptides is present in canine atopic skin.
Comparative immunology, microbiology and infectious diseases. 65:65-69 [DOI] 10.1016/j.cimid.2019.04.008.
2019
Dermatitis caused by autochthonous Cercopithifilaria bainae from a dog in Florida, USA: clinical, histological and parasitological diagnosis and treatment.
Veterinary dermatology. 30(1):68-e20 [DOI] 10.1111/vde.12701. [PMID] 30474318.
2019
Erysipeloid lesions caused by Erysipelothrix rhusiopathiae in a dog: clinical and histopathological findings, molecular diagnosis and treatment.
Veterinary dermatology. 30(5):434-e134 [DOI] 10.1111/vde.12773. [PMID] 31364229.
2019
Evaluation of the expression and distribution of Prune-1 in the skin of healthy dogs.
Veterinary dermatology. 30(5):446-447 [DOI] 10.1111/vde.12780. [PMID] 31286578.
2019
In vitro antimicrobial activity of topical otological antimicrobials and Tris-EDTA against resistant Staphylococcus pseudintermedius and Pseudomonas aeruginosa isolates from dogs.
Veterinary dermatology. 30(2):139-e40 [DOI] 10.1111/vde.12717.
2019
Isolation of Neisseria dumasiana from a deep bite wound infection in a dog.
Veterinary dermatology. 30(6):556-e168 [DOI] 10.1111/vde.12791. [PMID] 31486550.
2019
Peripheral blood-derived mesenchymal stem cells demonstrate immunomodulatory potential for therapeutic use in horses
PLoS One. 14(3) [DOI] 10.1371/journal.pone.0212642. [PMID] 30870461.
2019
Pilot study using five methods to evaluate skin barrier function in healthy dogs and in dogs with atopic dermatitis.
Veterinary dermatology. 30(2):121-e34 [DOI] 10.1111/vde.12723.
2019
Plasma membrane integrity and oxidative stress index outcomes of canine progenitor epidermal keratinocytes (CPEKs) exposed to virgin coconut oil (VCO).
Veterinary dermatology. 30(6) [DOI] 10.1111/vde.12800.
2019
Therapies in Canine Atopic Dermatitis: An Update.
The Veterinary clinics of North America. Small animal practice. 49(1):9-26 [DOI] 10.1016/j.cvsm.2018.08.002. [PMID] 30262146.
2018
Evaluation of the secretion of antimicrobial peptides and antimicrobial effect of skin wash in atopic and healthy dogs: a preliminary study.
Veterinary dermatology. 29(5):402-e132 [DOI] 10.1111/vde.12661. [PMID] 29963726.
2018
Evaluation on the effects of 0.1% Peumus boldus leaf and Spiraea ulmaria plant extract combination on bacterial colonization in canine atopic dermatitis: A preliminary randomized, placebo controlled, double-blinded study.
Research in veterinary science. 118:164-170 [DOI] 10.1016/j.rvsc.2018.02.006. [PMID] 29482177.
2018
Prevalence and zoonotic risk of tropical rat mite (Ornithonyssus bacoti ) in exotic companion mammals in southern Italy
Veterinary dermatology. 29(6):522-e174 [DOI] 10.1111/vde.12684.
2018
Single blinded, randomized, placebo-controlled study on the effects of ciclosporin on cutaneous barrier function and immunological response in atopic beagles.
Veterinary immunology and immunopathology. 197:93-101 [DOI] 10.1016/j.vetimm.2018.02.001. [PMID] 29475513.
2017
Evaluation of the in vitro effect of Boldo and Meadowsweet plant extracts on the expression of antimicrobial peptides and inflammatory markers in canine keratinocytes.
Research in veterinary science. 115:255-262 [DOI] 10.1016/j.rvsc.2017.05.021. [PMID] 28549300.
2017
Increased filaggrin-metabolizing enzyme activity in atopic skin: a pilot study using a canine model of atopic dermatitis.
Veterinary dermatology. 28(5):479-e111 [DOI] 10.1111/vde.12443. [PMID] 28393458.
2017
Randomized, double-blinded, placebo-controlled pilot study on the effects of topical blackcurrant emulsion enriched in essential fatty acids, ceramides and 18-beta glycyrrhetinic acid on clinical signs and skin barrier function in dogs with atopic dermatitis.
Veterinary dermatology. 28(6):577-e140 [DOI] 10.1111/vde.12467.
2017
Total skin electron therapy as treatment for epitheliotropic lymphoma in a dog.
Veterinary dermatology. 28(2):246-e65 [DOI] 10.1111/vde.12415. [PMID] 28133821.
2017
Tropical rat mite (Ornithonyssus bacoti) infestation in pet Syrian hamsters (Mesocricetus auratus) and their owner.
Veterinary dermatology. 28(2):256-257 [DOI] 10.1111/vde.12411. [PMID] 28025849.
2016
A comparative study of epidermal tight junction proteins in a dog model of atopic dermatitis.
Veterinary dermatology. 27(1):40-e11 [DOI] 10.1111/vde.12276. [PMID] 26663564.
2016
Can ultraviolet light C decrease the environmental burden of antimicrobial-resistant and -sensitive bacteria on textiles?
Veterinary dermatology. 27(6):457-e121 [DOI] 10.1111/vde.12377. [PMID] 27620856.
2016
Canine and Human Atopic Dermatitis: Two Faces of the Same Host-Microbe Interaction.
The Journal of investigative dermatology. 136(6):1087-1089 [DOI] 10.1016/j.jid.2016.03.015. [PMID] 27212648.
2016
Decreased expression of caspase-14 in an experimental model of canine atopic dermatitis.
Veterinary journal (London, England : 1997). 209:201-3 [DOI] 10.1016/j.tvjl.2015.11.020. [PMID] 26831171.
2015
Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification.
BMC veterinary research. 11 [DOI] 10.1186/s12917-015-0515-5. [PMID] 26260508.
2015
Evaluation of antimicrobial peptides and cytokine production in primary keratinocyte cell culture from healthy and atopic beagles.
Experimental dermatology. 24(4):317-9 [DOI] 10.1111/exd.12660. [PMID] 25660992.
2015
Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs.
Veterinary dermatology. 26(2):77-8 [DOI] 10.1111/vde.12207. [PMID] 25808534.
2015
Review: Clinical and histological manifestations of canine atopic dermatitis.
Veterinary dermatology. 26(2):79-e24 [DOI] 10.1111/vde.12196. [PMID] 25676252.
2015
Review: Innate immunity, lipid metabolism and nutrition in canine atopic dermatitis.
Veterinary dermatology. 26(2):104-e28 [DOI] 10.1111/vde.12199. [PMID] 25728538.
2015
Review: Lymphocytes, cytokines, chemokines and the T-helper 1-T-helper 2 balance in canine atopic dermatitis.
Veterinary dermatology. 26(2):124-e32 [DOI] 10.1111/vde.12205. [PMID] 25808535.
2015
Review: Pathogenesis of canine atopic dermatitis: skin barrier and host-micro-organism interaction.
Veterinary dermatology. 26(2):84-e25 [DOI] 10.1111/vde.12197. [PMID] 25683702.
2015
Review: Role of genetics and the environment in the pathogenesis of canine atopic dermatitis.
Veterinary dermatology. 26(2):95-e26 [DOI] 10.1111/vde.12198. [PMID] 25703290.
2015
Review: The role of antibodies, autoantigens and food allergens in canine atopic dermatitis.
Veterinary dermatology. 26(2):115-e30 [DOI] 10.1111/vde.12201. [PMID] 25728611.
2015
Survey of zoonotic dermatoses in client-owned exotic pet mammals in southern Italy.
Zoonoses and public health. 62(2):100-4 [DOI] 10.1111/zph.12100. [PMID] 24506806.
2014
Canine Antimicrobial Peptides Are Effective Against Resistant Bacteria and Yeasts
Veterinary Dermatology. 25(1):35+-e12 [DOI] 10.1111/vde.12091. [PMID] 24215268.
2014
Increased leptin mRNA expression in the blood of dogs naturally infected by Leishmania infantum.
Veterinary journal (London, England : 1997). 202(3):634-6 [DOI] 10.1016/j.tvjl.2014.10.010. [PMID] 25458880.
2014
Leporacarus gibbus infestation in client-owned rabbits and their owner.
Veterinary dermatology. 25(1):46-e17 [DOI] 10.1111/vde.12089. [PMID] 24325409.
2014
Prevalence of fur mites (Chirodiscoides caviae) in pet guinea pigs (Cavia porcellus) in southern Italy.
Veterinary dermatology. 25(2):135-7, e37 [DOI] 10.1111/vde.12110. [PMID] 24476091.
2013
Altered mRNA and protein expression of filaggrin in the skin of a canine animal model for atopic dermatitis.
Veterinary dermatology. 24(3):329-36, e73 [DOI] 10.1111/vde.12031. [PMID] 23668858.
2013
Evaluation of canine antimicrobial peptides in infected and noninfected chronic atopic skin.
Veterinary dermatology. 24(1):39-47.e10 [DOI] 10.1111/j.1365-3164.2012.01091.x. [PMID] 23331678.
2013
Investigation of the effect of probiotic exposure on filaggrin expression in an experimental model of canine atopic dermatitis.
Veterinary dermatology. 24(2):260-e57 [DOI] 10.1111/vde.12006. [PMID] 23432387.
2013
Multiple (disseminated) follicular cysts in five dogs and one cat.
The Veterinary record. 173(11) [DOI] 10.1136/vr.101701. [PMID] 23884156.
2013
Orodental diseases and dermatological disorders are highly associated in pet rabbits: a case-control study.
Veterinary dermatology. 24(5):531-e125 [DOI] 10.1111/vde.12052. [PMID] 23829169.
2013
Pour-on alphacypermethrin is an effective treatment for natural Werneckiella equi infection in donkeys (Equus asinus).
Veterinary dermatology. 24(5):556-7 [DOI] 10.1111/vde.12051. [PMID] 23826989.
2012
Early exposure to probiotics in a canine model of atopic dermatitis has long-term clinical and immunological effects.
Veterinary immunology and immunopathology. 146(2):185-9 [DOI] 10.1016/j.vetimm.2012.02.013. [PMID] 22436376.
2011
Expression and distribution of antimicrobial peptides in the skin of healthy beagles.
Veterinary dermatology. 22(1):61-7 [DOI] 10.1111/j.1365-3164.2010.00911.x. [PMID] 20646260.
2011
Expression and distribution of canine antimicrobial peptides in the skin of healthy and atopic beagles.
Veterinary immunology and immunopathology. 144(3-4):382-8 [DOI] 10.1016/j.vetimm.2011.08.004. [PMID] 21889803.
2011
Use of ciclosporin in a dog with canine juvenile sterile granulomatous dermatitis and lymphadenitis.
Veterinary dermatology. 22(3):287-8 [DOI] 10.1111/j.1365-3164.2010.00953.x. [PMID] 21251099.
2009
Post-traumatic peripheral arteriovenous fistula manifesting as digital haemorrhages in a cat: diagnosis with contrast-enhanced 3D CT imaging.
Veterinary dermatology. 20(3):206-13 [DOI] 10.1111/j.1365-3164.2009.00754.x. [PMID] 19374722.
2008
Cutaneous sterile pyogranuloma/granuloma syndrome in a dog.
The Canadian veterinary journal = La revue veterinaire canadienne. 49(12):1204-7 [PMID] 19252712.
View on: PubMed
2004
Seroprevalence of Neospora spp. in asymptomatic horses in Italy.
Veterinary parasitology. 123(1-2):11-5 [PMID] 15265566.
View on: PubMed

Grants

Aug 2021 ACTIVE
Evaluation of anti-inflammatory, anti-oxidant and cytotoxicity effects of C60 on canine keratinocytes
Role: Principal Investigator
Funding: FULLER RESEARCH
Jun 2021 ACTIVE
The effect of probiotic vs. placebo on the clinical response and cytokine profile in felines with allergic dermatitis: a randomized, double blinded controlled study.
Role: Co-Investigator
Funding: NESTLE PURINA PETCARE COMPANY
Feb 2021 ACTIVE
Intradermal immunotherapy with a heat-killed actinomycetales bacterin preparation as adjunctive treatment for canine pythiosis: a multicentric, randomized, controlled, clinical trial
Role: Principal Investigator
Funding: AMER COL OF VET DERMATOLOGY
Jan 2021 ACTIVE
Effect of cytokines on S. pseudintermedius in planktonic as well as in biofilm state
Role: Other
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Sep 2020 ACTIVE
Investigation on the in vitro effects of resveratrol on canine peripheral blood mononuclear cells harvested from healthy and atopic dogs
Role: Principal Investigator
Funding: WESTIE FOUNDATION OF AMERICA
Aug 2020 – Jul 2021
Effect(s) of atopic dermatitis-associated cytokines on Staphylococcus pseudintermedius: an in vitro and ex vivo study
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
May 2020 ACTIVE
Investigation on the molecular crosstalk between canine atopic skin and microbes: unraveling potential pathomechanisms for chronic recurrent skin infections.
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Jan 2020 ACTIVE
Ultrastructural evaluation on the alterations of host defense peptide secretion present in the canine atopic skin: a correlative light and electron microscopy study
Role: Principal Investigator
Funding: EUROPEAN SOC OF VETERINARY DERMATOLOGY
May 2019 – Dec 2020
Investigation on the effects of Linkskin? spray on the cutaneous microbiome in canine atopic dermatitis
Role: Principal Investigator
Funding: DRN SRL
Feb 2019 – Jan 2021
Evaluation of the serum and cutaneous levels of chemokines (CCL17, CCL22, CCL27, and CCL28) in atopic dogs and their correlation with severity of canine atopic dermatitis
Role: Principal Investigator
Funding: AMER KENNEL CLUB
Nov 2018 – Jan 2021
Effects of the New Epiotic on bacterial load and antimicrobial peptides secretion in the ears of atopic dogs: a double blinded, randomized, placebo controlled study
Role: Principal Investigator
Funding: VIRBAC
Jun 2018 – May 2019
Anti-inflammatory and cytotoxicity study of nanoparticles with and without copper
Role: Principal Investigator
Funding: EARTH SCIENCE LABORATORIES
May 2018 – Oct 2019
In vitro efficacy of nano-sulfur against planktonic and biofilm state of resistant bacteria
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Aug 2017 – Oct 2019
Pilot Study: in vitro efficacy of KETOCHLOR ingredients against different bacterial and fungal strains.
Role: Principal Investigator
Funding: VIRBAC
Dec 2015 – Dec 2017
Resveratrol: the new age of treating atopic dermatitis in dogs
Role: Principal Investigator
Funding: UF FOU
Jul 2015 – Jun 2017
Is defective secretion of antimicrobial peptides
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
May 2015 – Nov 2017
Is defective secretion of antimicrobial peptides
Role: Principal Investigator
Funding: UF FOU

Education

Doctor of Philosophy In Veterinary Medical Sciences
2013 · University of Illinois at Urbana-Campaign
Master of Science in Veterinary Medical Sciences
2010 · University of Illinois at Urbana-Campaign
Veterinary Dermatology Residency
2010 · University of Illinois at Urbana-Campaign
Veterinary Dermatology Internship
2007 · North Carolina State University
Research Doctorate
2006 · University of Naples "Federico II"
Doctor in Veterinary Medicine
2001 · University of Naples "Federico II"

Teaching Profile

Courses Taught
2017-2021
VME6905 Problems in Veterinary Medical Sciences
2017-2021
VEM5388 Sa Dermatology
2017-2021
VEM5171 Vet Pharmacology
2015-2021
VEM5869 Senior Clk Dermatol
2020-2021
VEM5893 Micro Parasit Serolog
2016-2021
VEM5387 Vet Dermatology
2018-2021
VEM5204 Pnt Care Clin Skill 4
2016
VEM5902 Supervised Teach Dev
2015
VME6934 Topics in Veterinary Medical Sciences

Contact Details

Phones:
Business:
(352) 392-2235
Emails:
Business:
dsantoro@ufl.edu