Simon O Owino

Simon O Owino

RES AST PROF

Department: Department of Infectious Diseases & Immunology
Business Phone: (352) 294-4143
Business Email: sowino@ufl.edu

Research Profile

Dr. Simon Odera Owino is an experienced research professor with a demonstrated history of working in the higher education industry. Skilled in parasitology, research design, molecular biology, cell culture, and genetic engineering, Dr. Owino is a strong education professional with a Doctor of Philosophy (Ph.D.) focused in Infectious Diseases from the University of Georgia.

Dr. Owino’s current research mainly focuses on immunological crosstalk within the fetal-maternal interphase during malaria infection. To accomplish this goal, Dr. Owino harvests and cultures primary trophoblast cells, which are placental cells in contact with maternal blood, as well as maintains an immortalized cell line, BeWo, used as mimics for primary trophoblast. In addition to the work detailed above, Dr. Owino uses a mouse model designed to understand the course and impact of malaria infection during pregnancy. He is also interested in understanding intricate processes of hypoxia during malaria and how these processes influence pregnancy outcome.

Publications

2018
Evaluation of a temperature-restricted, mucosal tuberculosis vaccine in guinea pigs.
Tuberculosis (Edinburgh, Scotland). 113:179-188 [DOI] 10.1016/j.tube.2018.10.006. [PMID] 30514501.
2017
Broadened immunity and protective responses with emulsion-adjuvanted H5 COBRA-VLP vaccines.
Vaccine. 35(38):5209-5216 [DOI] 10.1016/j.vaccine.2017.07.107. [PMID] 28789850.
2017
Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains.
PloS one. 12(11) [DOI] 10.1371/journal.pone.0185666. [PMID] 29091724.
2015
Differential roles of inflammation and apoptosis in initiation of mid-gestational abortion in malaria-infected C57BL/6 and A/J mice.
Placenta. 36(7):738-49 [DOI] 10.1016/j.placenta.2015.04.007. [PMID] 25956987.
2012
Maternal malaria induces a procoagulant and antifibrinolytic state that is embryotoxic but responsive to anticoagulant therapy.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0031090. [PMID] 22347435.
2012
Sequence polymorphism, segmental recombination and toggling amino acid residues within the DBL3X domain of the VAR2CSA placental malaria antigen.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0031565. [PMID] 22347496.
2012
Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya.
Malaria journal. 11 [DOI] 10.1186/1475-2875-11-134. [PMID] 22540158.
2011
Natural hemozoin stimulates syncytiotrophoblast to secrete chemokines and recruit peripheral blood mononuclear cells.
Placenta. 32(8):579-85 [DOI] 10.1016/j.placenta.2011.05.003. [PMID] 21632106.
2009
C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria.
PloS one. 4(3) [DOI] 10.1371/journal.pone.0004953. [PMID] 19308263.
2009
Human immunodeficiency virus co-infection increases placental parasite density and transplacental malaria transmission in Western Kenya.
The American journal of tropical medicine and hygiene. 80(1):119-25 [PMID] 19141849.
View on: PubMed

Education

Doctor of Philosophy in Immunology and Infectious Disease
2012 · The University of Georgia
Master of Science in Cell and Molecular Biology
2007 · Maseno University, Kenya

Contact Details

Phones:
Business:
(352) 294-4143
Emails:
Business:
sowino@ufl.edu

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