Dianne McFarlane

Dianne McFarlane, DVM, PhD, MS

CHAIR & PROF

Department: Large Animal Clinical Sciences
Business Phone: (352) 294-4320
Business Email: dmcfarlane1@ufl.edu

Teaching Profile

Courses Taught
2022-2024
VME6905 Problems in Veterinary Medical Sciences
2022
VEM5171 Vet Pharmacology
2023-2024
VEM5289 Lg An Clin Pharmacol
2023-2024
VEM5278L Theriogenology
2023-2024
VEM5335 Equine Medicine

Board Certifications

  • Large Animal Internal Medicine
    American College of Veterinary Internal Medicine

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-4836-8069

Areas of Interest
  • Aging and Age related disease
  • Equine Endocrinology
  • Pituitary pars intermedia dysfunction

Publications

2024
BEVA primary care clinical guidelines: Diagnosis and management of equine pituitary pars intermedia dysfunction.
Equine veterinary journal. 56(2):220-242 [DOI] 10.1111/evj.14009. [PMID] 37795557.
2024
Fecal microbiota composition, serum metabolomics, and markers of inflammation in dogs fed a raw meat-based diet compared to those on a kibble diet.
Frontiers in veterinary science. 11 [DOI] 10.3389/fvets.2024.1328513. [PMID] 38694479.
2023
Adverse health events and recommended health research priorities in agility dogs as reported by dog owners.
Frontiers in veterinary science. 10 [DOI] 10.3389/fvets.2023.1127632. [PMID] 36992973.
2023
Immunosenescence and inflammaging in the aged horse.
Immunity & ageing : I & A. 20(1) [DOI] 10.1186/s12979-022-00325-5. [PMID] 36609345.
2022
At UF, caseload and approach set us apart.
Journal of the American Veterinary Medical Association. 260(12) [DOI] 10.2460/javma.22.07.0279. [PMID] 36006912.
2022
Thromboelastography in obese horses with insulin dysregulation compared to healthy controls
Journal of Veterinary Internal Medicine. 36(3):1131-1138 [DOI] 10.1111/jvim.16421. [PMID] 35429197.
2021
Clinical health markers in dogs fed raw meat-based or commercial extruded kibble diets
Journal of Animal Science. 99(6) [DOI] 10.1093/jas/skab133. [PMID] 33939804.
2021
Effects of Chronic Viral Infection on Lymphocyte Populations in Middle-aged Baboons (Papio anubis).
Comparative medicine. 71(2):177-187 [DOI] 10.30802/AALAS-CM-20-000068. [PMID] 33579397.
2019
Characterization of Baboon Cytomegalovirus Infection in Healthy Adult Baboons (Papio anubis).
Comparative medicine. 69(1):55-62 [DOI] 10.30802/AALAS-CM-18-000050. [PMID] 30704552.
2019
Diagnostic Testing for Equine Endocrine Diseases: Confirmation Versus Confusion.
The Veterinary clinics of North America. Equine practice. 35(2):327-338 [DOI] 10.1016/j.cveq.2019.03.005. [PMID] 31076223.
2019
Genome-Wide Association Analyses of Equine Metabolic Syndrome Phenotypes in Welsh Ponies and Morgan Horses
Genes. 10(11) [DOI] https://doi.org/10.3390/genes10110893.
2019
Genome-Wide Association Analyses of Equine Metabolic Syndrome Phenotypes in Welsh Ponies and Morgan Horses.
Genes. 10(11) [DOI] 10.3390/genes10110893. [PMID] 31698676.
2018
Comparison of two methods for measurement of equine adrenocorticotropin.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 30(2):233-237 [DOI] 10.1177/1040638717752216. [PMID] 29284383.
2017
Efficacy of the early administration of valacyclovir hydrochloride for the treatment of neuropathogenic equine herpesvirus type-1 infection in horses.
American journal of veterinary research. 78(10):1126-1139 [DOI] 10.2460/ajvr.78.10.1126. [PMID] 28945127.
2016
Immune Dysfunction in Aged Horses.
The Veterinary clinics of North America. Equine practice. 32(2):333-41 [DOI] 10.1016/j.cveq.2016.04.009. [PMID] 27329495.
2016
Relationship of skeletal muscle inflammation with obesity and obesity-associated hyperinsulinemia in horses.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 80(3):217-24 [PMID] 27408335.
2015
Neutrophil function in healthy aged horses and horses with pituitary dysfunction.
Veterinary immunology and immunopathology. 165(3-4):99-106 [DOI] 10.1016/j.vetimm.2015.04.006. [PMID] 25962580.
2015
Relationship of oxidative stress in skeletal muscle with obesity and obesity-associated hyperinsulinemia in horses.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 79(4):329-38 [PMID] 26424915.
2014
Age- and gender-associated changes in the concentrations of serum TGF-1β, DHEA-S and IGF-1 in healthy captive baboons (Papio hamadryas anubis).
General and comparative endocrinology. 195:21-7 [DOI] 10.1016/j.ygcen.2013.10.004. [PMID] 24161750.
2014
Comparison of two methods for measurement of equine insulin.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 26(4):527-530 [DOI] 10.1177/1040638714536560. [PMID] 24928598.
2014
Oxidative modification, inflammation and amyloid in the normal and diabetic cat pancreas.
Journal of comparative pathology. 151(4):352-62 [DOI] 10.1016/j.jcpa.2014.06.004. [PMID] 25124331.
2014
The effects of age and cytomegalovirus on markers of inflammation and lymphocyte populations in captive baboons.
PloS one. 9(9) [DOI] 10.1371/journal.pone.0107167. [PMID] 25244034.
2013
Antibody responses to natural rattlesnake envenomation and a rattlesnake toxoid vaccine in horses.
Clinical and vaccine immunology : CVI. 20(5):732-7 [DOI] 10.1128/CVI.00004-13. [PMID] 23515015.
2013
Development of a double sandwich fluorescent ELISA to detect rattlesnake venom in biological samples from horses with a clinical diagnosis of rattlesnake bite.
Toxicon : official journal of the International Society on Toxinology. 73:63-8 [DOI] 10.1016/j.toxicon.2013.06.022. [PMID] 23834918.
2012
Cardiotoxicity, inflammation, and immune response after rattlesnake envenomation in the horse.
Journal of veterinary internal medicine. 26(6):1457-63 [DOI] 10.1111/j.1939-1676.2012.01022.x. [PMID] 23113840.
2012
Neutrophil and cytokine dysregulation in hyperinsulinemic obese horses.
Veterinary immunology and immunopathology. 145(1-2):283-9 [DOI] 10.1016/j.vetimm.2011.11.013. [PMID] 22169327.
2012
The effect of season on inflammatory response in captive baboons.
Journal of medical primatology. 41(6):341-8 [DOI] 10.1111/j.1600-0684.2012.00560.x. [PMID] 22905903.
2011
Age-associated alteration in innate immune response in captive baboons.
The journals of gerontology. Series A, Biological sciences and medical sciences. 66(12):1309-17 [DOI] 10.1093/gerona/glr146. [PMID] 21860017.
2011
Equine pituitary pars intermedia dysfunction.
The Veterinary clinics of North America. Equine practice. 27(1):93-113 [DOI] 10.1016/j.cveq.2010.12.007. [PMID] 21392656.
2011
The effect of geographic location, breed, and pituitary dysfunction on seasonal adrenocorticotropin and α-melanocyte-stimulating hormone plasma concentrations in horses.
Journal of veterinary internal medicine. 25(4):872-81 [DOI] 10.1111/j.1939-1676.2011.0745.x. [PMID] 21745243.
2011
α-Melanocyte–stimulating hormone and adrenocorticotropin concentrations in response to thyrotropin-releasing hormone and comparison with adrenocorticotropin concentration after domperidone administration in healthy horses and horses with pituitary pars intermedia dysfunction.
Journal of the American Veterinary Medical Association. 238(10):1305-15 [DOI] 10.2460/javma.238.10.1305. [PMID] 21568777.
2010
Fecal egg counts after anthelmintic administration to aged horses and horses with pituitary pars intermedia dysfunction.
Journal of the American Veterinary Medical Association. 236(3):330-4 [DOI] 10.2460/javma.236.3.330. [PMID] 20113248.
2010
More on cultivating veterinarian-scientists.
Journal of the American Veterinary Medical Association. 237(12) [PMID] 21229803.
2010
Neuroendocrine and non-neuroendocrine markers of inflammation associated with performance in endurance horses.
Equine veterinary journal. Supplement. (38):123-8 [DOI] 10.1111/j.2042-3306.2010.00256.x. [PMID] 21058993.
2009
Evaluation of plasma ACTH, alpha-melanocyte-stimulating hormone, and insulin concentrations during various photoperiods in clinically normal horses and ponies and those with pituitary pars intermedia dysfunction.
Journal of the American Veterinary Medical Association. 235(6):715-22 [DOI] 10.2460/javma.235.6.715. [PMID] 19751169.
2008
Cytokine dysregulation in aged horses and horses with pituitary pars intermedia dysfunction.
Journal of veterinary internal medicine. 22(2):436-42 [DOI] 10.1111/j.1939-1676.2008.0076.x. [PMID] 18371032.
2007
Advantages and limitations of the equine disease, pituitary pars intermedia dysfunction as a model of spontaneous dopaminergic neurodegenerative disease.
Ageing research reviews. 6(1):54-63 [PMID] 17374512.
2006
Alpha-melanocyte stimulating hormone release in response to thyrotropin releasing hormone in healthy horses, horses with pituitary pars intermedia dysfunction and equine pars intermedia explants.
Domestic animal endocrinology. 30(4):276-88 [PMID] 16115743.
2005
Agreement in histologic assessments of the pituitary pars intermedia in aged horses.
American journal of veterinary research. 66(12):2055-9 [PMID] 16379646.
2005
Systemic and pituitary pars intermedia antioxidant capacity associated with pars intermedia oxidative stress and dysfunction in horses.
American journal of veterinary research. 66(12):2065-72 [PMID] 16379648.
2005
Variation in plasma adrenocorticotropic hormone concentration and dexamethasone suppression test results with season, age, and sex in healthy ponies and horses.
Journal of veterinary internal medicine. 19(2):217-22 [PMID] 15822567.
2004
Correlation between plasma alpha-melanocyte-stimulating hormone concentration and body mass index in healthy horses.
American journal of veterinary research. 65(11):1469-73 [PMID] 15566082.
2004
Effects of season and sample handling on measurement of plasma alpha-melanocyte-stimulating hormone concentrations in horses and ponies.
American journal of veterinary research. 65(11):1463-8 [PMID] 15566081.

Grants

Sep 2023 ACTIVE
Are peptide signatures created using machine learning the future for early diagnosis of PPID? Development and Application of a Novel Diagnostic Test for PPID
Role: Principal Investigator
Funding: MORRIS ANIMAL FOU
Aug 2023 ACTIVE
FL Equine Assessment and Surveillance
Role: Principal Investigator
Funding: US DEPT OF AG APHIS
Nov 2022 – Feb 2024
Investigation of genetic risk alleles for pituitary pars intermedia dysfunction
Role: Principal Investigator
Funding: UNIV OF MINNESOTA via MORRIS ANIMAL FOU
Oct 2016 ACTIVE
Sea Turtle NOAA/NMFS work site
Role: Principal Investigator
Funding: US DEPT OF COMMERCE NATL MARINE FISH SER via US DEPT OF COMM NATL OCEANIC & ATMOS ADM

Education

PhD
2005 · Atlantic Veterinary College, University of Prince Edward Island
Doctor of Veterinary Medicine
1992 · University of California, Davis

Contact Details

Phones:
Business:
(352) 294-4320
Emails:
Addresses:
Business Mailing:
PO Box 100136
GAINESVILLE FL 32610