Christopher J Martyniuk

Christopher J Martyniuk,

ASO PROF

Department: Department of Physiological Sciences
Business Phone: (352) 294-4636
Business Email: cmartyn@ufl.edu

Accomplishments

UF Term Professorship
2020-2023 · University of Florida
Award for Research Excellence
2018 · Zoetis Animal Health
Bob Boutilier New Investigator Award
2013 · Canadian Society of Zoology
The Gorbman – Bern New Independent Investigator Award
2013 · North American Society for Comparative Endocrinology

Research Profile

We study how environmental contaminants impact a broad range of biological systems such as the nervous system, endocrine system, and gut-microbiome axis. We use neuronal cell models (dopaminergic rat and human cells) and zebrafish in vivo toxicity assays to determine the mechanisms of environmental toxicants, focusing on pesticides that have been associated with neurodegenerative diseases and the mitochondria. We are also using CRISPR gene editing approaches to understand the functional significance of genes during pesticide exposures. Specialties: Molecular toxicology, omics, environmental science, neurodegeneration, high throughput in vitro screening, neurotoxicology

Publications

2021
A comprehensive review of strobilurin fungicide toxicity in aquatic species: Emphasis on mode of action from the zebrafish model.
Environmental pollution (Barking, Essex : 1987). 275 [DOI] 10.1016/j.envpol.2021.116671. [PMID] 33582629.
2021
Characterization of the GABAergic system in Asian clam Corbicula fluminea: Phylogenetic analysis, tissue distribution, and response to the aquatic contaminant carbamazepine.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 239 [DOI] 10.1016/j.cbpc.2020.108896. [PMID] 32949817.
2021
Current topics in omics, ecotoxicology, and environmental science.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 38 [DOI] 10.1016/j.cbd.2020.100782. [PMID] 33582457.
2021
Environmentally relevant concentrations of sertraline disrupts behavior and the brain and liver transcriptome of juvenile yellow catfish (Tachysurus fulvidraco): Implications for the feeding and growth axis.
Journal of hazardous materials. 409 [DOI] 10.1016/j.jhazmat.2020.124974. [PMID] 33450510.
2021
Evaluation and comparison of the mitochondrial and developmental toxicity of three strobilurins in zebrafish embryo/larvae.
Environmental pollution (Barking, Essex : 1987). 270 [DOI] 10.1016/j.envpol.2020.116277. [PMID] 33360065.
2021
Fucoidan ameliorates acute and sub-chronic in vivo toxicity of the fungicide cholorothalonil in Oreochromis niloticus (Nile tilapia).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 245 [DOI] 10.1016/j.cbpc.2021.109035. [PMID] 33774206.
2021
Identification of active and inactive agonists/antagonists of estrogen receptor based on Tox21 10K compound library: Binomial analysis and structure alert.
Ecotoxicology and environmental safety. 214 [DOI] 10.1016/j.ecoenv.2021.112114. [PMID] 33711575.
2021
In Parkinson’s patient-derived dopamine neurons, the triplication of α-synuclein locus induces distinctive firing pattern by impeding D2 receptor autoinhibition.
Acta neuropathologica communications. 9(1) [DOI] 10.1186/s40478-021-01203-9. [PMID] 34099060.
2021
Lipidomics reveals multiple stressor effects (temperature × mitochondrial toxicant) in the zebrafish embryo toxicity test.
Chemosphere. 264(Pt 1) [DOI] 10.1016/j.chemosphere.2020.128472. [PMID] 33039916.
2021
Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA).
Neurotoxicology. 85:160-172 [DOI] 10.1016/j.neuro.2021.05.009. [PMID] 34029635.
2021
Microbiome analysis and predicted relative metabolomic turnover suggest bacterial heme and selenium metabolism are altered in the gastrointestinal system of zebrafish (Danio rerio) exposed to the organochlorine dieldrin.
Environmental pollution (Barking, Essex : 1987). 268(Pt B) [DOI] 10.1016/j.envpol.2020.115715. [PMID] 33069042.
2021
Microbiome Composition and Function in Aquatic Vertebrates: Small Organisms Making Big Impacts on Aquatic Animal Health.
Frontiers in microbiology. 12 [DOI] 10.3389/fmicb.2021.567408. [PMID] 33776947.
2021
Mitochondria of teleost radial glia: A novel target of neuroendocrine disruption by environmental chemicals?
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 243 [DOI] 10.1016/j.cbpc.2021.108995. [PMID] 33545344.
2021
Mitochondrial and transcriptome responses in rat dopaminergic neuronal cells following exposure to the insecticide fipronil.
Neurotoxicology. 85:173-185 [DOI] 10.1016/j.neuro.2021.05.011. [PMID] 34044035.
2021
Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure.
Ecotoxicology and environmental safety. 208 [DOI] 10.1016/j.ecoenv.2020.111700. [PMID] 33396031.
2021
Plastics in our water: Fish microbiomes at risk?
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 39 [DOI] 10.1016/j.cbd.2021.100834. [PMID] 33930774.
2021
Recent advances in comparative epigenetics.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 37 [DOI] 10.1016/j.cbd.2020.100783. [PMID] 33524767.
2021
Relative comparison of strobilurin fungicides at environmental levels: Focus on mitochondrial function and larval activity in early staged zebrafish (Danio rerio).
Toxicology. 452 [DOI] 10.1016/j.tox.2021.152706. [PMID] 33548355.
2021
The agrochemical S-metolachlor disrupts molecular mediators and morphology of the swim bladder: Implications for locomotor activity in zebrafish (Danio rerio).
Ecotoxicology and environmental safety. 208 [DOI] 10.1016/j.ecoenv.2020.111641. [PMID] 33396161.
2021
Tumor Necrosis Factor Alpha and the Gastrointestinal Epithelium: Implications for the Gut-Brain Axis and Hypertension.
Cellular and molecular neurobiology. [DOI] 10.1007/s10571-021-01044-z. [PMID] 33594519.
2021
Virtual Special Issue of the Fifth Biennial Meeting of the North American Society for Comparative Endocrinology (Sociedad Norteamericana de Endocrinología Comparada; Societé Nord-Americaine d’Endocrinologie Comparée).
General and comparative endocrinology. 308 [DOI] 10.1016/j.ygcen.2021.113770. [PMID] 33819475.
2020
Advancing the fathead minnow (Pimephales promelas) as a model for immunotoxicity testing: Characterization of the renal transcriptome following Yersinia ruckeri infection.
Fish & shellfish immunology. 103:472-480 [DOI] 10.1016/j.fsi.2020.05.008. [PMID] 32439514.
2020
An in vivo brain-bacteria interface: the developing brain as a key regulator of innate immunity.
NPJ Regenerative medicine. 5 [DOI] 10.1038/s41536-020-0087-2. [PMID] 32047653.
2020
Antineoplastic Agents: Environmental Prevalence and Adverse Outcomes in Aquatic Organisms.
Environmental toxicology and chemistry. 39(5):967-985 [DOI] 10.1002/etc.4687. [PMID] 32266737.
2020
Are we forgetting the “proteomics” in multi-omics ecotoxicology?
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100751. [PMID] 33142247.
2020
Assessing the toxicity of the benzamide fungicide zoxamide in zebrafish (Danio rerio): Towards an adverse outcome pathway for beta-tubulin inhibitors.
Environmental toxicology and pharmacology. 78 [DOI] 10.1016/j.etap.2020.103405. [PMID] 32446185.
2020
Butylated hydroxytoluene induces hyperactivity and alters dopamine-related gene expression in larval zebrafish (Danio rerio).
Environmental pollution (Barking, Essex : 1987). 257 [DOI] 10.1016/j.envpol.2019.113624. [PMID] 31780362.
2020
Comparative epigenetics in animal physiology: An emerging frontier.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100745. [PMID] 33126028.
2020
Correction: Social status regulates the hepatic miRNAome in rainbow trout: Implications for posttranscriptional regulation of metabolic pathways.
PloS one. 15(5) [DOI] 10.1371/journal.pone.0233827. [PMID] 32437451.
2020
Development and Molecular Investigation into the Effects of Carbamazepine Exposure in the Zebrafish (Danio rerio).
International journal of environmental research and public health. 17(23) [DOI] 10.3390/ijerph17238882. [PMID] 33260372.
2020
Ecotoxico-lipidomics: An emerging concept to understand chemical-metabolic relationships in comparative fish models.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100742. [PMID] 32956922.
2020
Elucidating mechanisms of immunotoxicity by benzotriazole ultraviolet stabilizers in zebrafish (Danio rerio): Implication of the AHR-IL17/IL22 immune pathway.
Environmental pollution (Barking, Essex : 1987). 262 [DOI] 10.1016/j.envpol.2020.114291. [PMID] 32146360.
2020
Evaluation of Microbiome-Host Relationships in the Zebrafish Gastrointestinal System Reveals Adaptive Immunity Is a Target of Bis(2-ethylhexyl) Phthalate (DEHP) Exposure.
Environmental science & technology. 54(9):5719-5728 [DOI] 10.1021/acs.est.0c00628. [PMID] 32255618.
2020
Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio): Altered microbial diversity, functionality, and network connectivity.
Environmental pollution (Barking, Essex : 1987). 265(Pt B) [DOI] 10.1016/j.envpol.2020.114496. [PMID] 32806437.
2020
Genetic ablation of bone marrow beta-adrenergic receptors in mice modulates miRNA-transcriptome networks of neuroinflammation in the paraventricular nucleus.
Physiological genomics. 52(4):169-177 [DOI] 10.1152/physiolgenomics.00001.2020. [PMID] 32089076.
2020
Getting the most out of reductionist approaches in comparative biochemistry and physiology.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 250 [DOI] 10.1016/j.cbpb.2020.110483. [PMID] 32717217.
2020
Investigation into the sub-lethal effects of the triazole fungicide triticonazole in zebrafish (Danio rerio) embryos/larvae.
Environmental toxicology. 35(2):254-267 [DOI] 10.1002/tox.22862. [PMID] 31670470.
2020
Morphometric and proteomic responses of early-life stage rainbow trout (Oncorhynchus mykiss) to the aquatic herbicide diquat dibromide.
Aquatic toxicology (Amsterdam, Netherlands). 222 [DOI] 10.1016/j.aquatox.2020.105446. [PMID] 32092595.
2020
Neurotoxicity assessment of triazole fungicides on mitochondrial oxidative respiration and lipids in differentiated human SH-SY5Y neuroblastoma cells.
Neurotoxicology. 80:76-86 [DOI] 10.1016/j.neuro.2020.06.009. [PMID] 32585290.
2020
Organochlorine pesticides: Agrochemicals with potent endocrine-disrupting properties in fish.
Molecular and cellular endocrinology. 507 [DOI] 10.1016/j.mce.2020.110764. [PMID] 32112812.
2020
Perspectives on transcriptomics in animal physiology studies.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 250 [DOI] 10.1016/j.cbpb.2020.110490. [PMID] 32798690.
2020
Regulation of endocrine systems by the microbiome: Perspectives from comparative animal models.
General and comparative endocrinology. 292 [DOI] 10.1016/j.ygcen.2020.113437. [PMID] 32061639.
2020
Residual molecular and behavioral effects of the phenylpyrazole pesticide fipronil in larval zebrafish (Danio rerio) following a pulse embryonic exposure.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100743. [PMID] 32977147.
2020
Sodium arsenite toxicity on hematology indices and reproductive parameters in Teddy goat bucks and their amelioration with vitamin C.
Environmental science and pollution research international. 27(13):15223-15232 [DOI] 10.1007/s11356-020-08049-z. [PMID] 32072415.
2020
Steroidogenic acute regulatory protein transcription is regulated by estrogen receptor signaling in largemouth bass ovary.
General and comparative endocrinology. 286 [DOI] 10.1016/j.ygcen.2019.113300. [PMID] 31678557.
2020
Sub-lethal toxicity assessment of the phenylurea herbicide linuron in developing zebrafish (Danio rerio) embryo/larvae.
Neurotoxicology and teratology. 81 [DOI] 10.1016/j.ntt.2020.106917. [PMID] 32712134.
2020
The effect of fucoidan or potassium permanganate on growth performance, intestinal pathology, and antioxidant status in Nile tilapia (Oreochromis niloticus).
Fish physiology and biochemistry. 46(6):2109-2131 [DOI] 10.1007/s10695-020-00858-w. [PMID] 32829475.
2020
The organochlorine pesticide toxaphene reduces non-mitochondrial respiration and induces heat shock protein 70 expression in early-staged zebrafish (Danio rerio).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 228 [DOI] 10.1016/j.cbpc.2019.108669. [PMID] 31712185.
2020
The pyrethroid esfenvalerate induces hypoactivity and decreases dopamine transporter expression in embryonic/larval zebrafish (Danio rerio).
Chemosphere. 243 [DOI] 10.1016/j.chemosphere.2019.125416. [PMID] 31995874.
2020
Toxicity assessment of the herbicide acetochlor in the human liver carcinoma (HepG2) cell line.
Chemosphere. 243 [DOI] 10.1016/j.chemosphere.2019.125345. [PMID] 31739254.
2020
Transcriptome and physiological effects of toxaphene on the liver-gonad reproductive axis in male and female largemouth bass (Micropterus salmoides).
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100746. [PMID] 32992212.
2020
Transcriptome network data in larval zebrafish (Danio rerio) following exposure to the phenylpyrazole fipronil.
Data in brief. 33 [DOI] 10.1016/j.dib.2020.106413. [PMID] 33134444.
2020
Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish.
General and comparative endocrinology. 286 [DOI] 10.1016/j.ygcen.2019.113325. [PMID] 31733209.
2019
Biological effects of the benzotriazole ultraviolet stabilizers UV-234 and UV-320 in early-staged zebrafish (Danio rerio).
Environmental pollution (Barking, Essex : 1987). 245:272-281 [DOI] 10.1016/j.envpol.2018.10.130. [PMID] 30439637.
2019
Carbamazepine disrupts molting hormone signaling and inhibits molting and growth of Eriocheir sinensis at environmentally relevant concentrations.
Aquatic toxicology (Amsterdam, Netherlands). 208:138-145 [DOI] 10.1016/j.aquatox.2019.01.010. [PMID] 30669117.
2019
Comparative physiology and aquaculture: Toward Omics-enabled improvement of aquatic animal health and sustainable production.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 31 [DOI] 10.1016/j.cbd.2019.100603. [PMID] 31260856.
2019
Computational in Vitro Toxicology Uncovers Chemical Structures Impairing Mitochondrial Membrane Potential.
Journal of chemical information and modeling. 59(2):702-712 [DOI] 10.1021/acs.jcim.8b00433. [PMID] 30645939.
2019
Developmental neurotoxicity of maneb: Notochord defects, mitochondrial dysfunction and hypoactivity in zebrafish (Danio rerio) embryos and larvae.
Ecotoxicology and environmental safety. 170:227-237 [DOI] 10.1016/j.ecoenv.2018.11.110. [PMID] 30529917.
2019
Developmental toxicity of the fungicide ziram in zebrafish (Danio rerio).
Chemosphere. 214:303-313 [DOI] 10.1016/j.chemosphere.2018.09.105. [PMID] 30265938.
2019
Developmental toxicity of the triazole fungicide cyproconazole in embryo-larval stages of zebrafish (Danio rerio).
Environmental science and pollution research international. 26(5):4913-4923 [DOI] 10.1007/s11356-018-3957-z. [PMID] 30569354.
2019
Dichloroacetate-induced peripheral neuropathy.
International review of neurobiology. 145:211-238 [DOI] 10.1016/bs.irn.2019.05.003. [PMID] 31208525.
2019
Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate.
Environmental pollution (Barking, Essex : 1987). 245:1086-1094 [DOI] 10.1016/j.envpol.2018.11.032. [PMID] 30682743.
2019
Guest editors’ introduction – Special issue of the fifth biennial meeting of the North American Society for Comparative Endocrinology (Sociedad Norteamericana de Endocrinología Comparada; Societé Nord-Americaine d’Endocrinologie Comparée).
General and comparative endocrinology. 283 [DOI] 10.1016/j.ygcen.2019.113222. [PMID] 31319062.
2019
Hair follicle miRNAs: a novel biomarker for primary blast Induced-Mild traumatic brain injury
Biomarkers. 166-179 [DOI] 10.1080/1354750X.2018.1531929.
2019
Hepatic proteome network data in zebrafish (Danio rerio) liver following dieldrin exposure.
Data in brief. 25 [DOI] 10.1016/j.dib.2019.104351. [PMID] 31453304.
2019
Hydrotalcite-based CeNiAl mixed oxides for SO2 adsorption and oxidation.
Environmental technology. 40(28):3678-3688 [DOI] 10.1080/09593330.2018.1485749. [PMID] 29869948.
2019
Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats.
Acta physiologica (Oxford, England). 226(2) [DOI] 10.1111/apha.13256. [PMID] 30656835.
2019
Label-free and iTRAQ proteomics analysis in the liver of zebrafish (Danio rerio) following dietary exposure to the organochlorine pesticide dieldrin.
Journal of proteomics. 202 [DOI] 10.1016/j.jprot.2019.04.012. [PMID] 31022476.
2019
Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways.
Environmental toxicology and chemistry. 38(8):1625-1634 [DOI] 10.1002/etc.4453. [PMID] 31034624.
2019
Long-Term Exposure to Environmental Concentrations of Azoxystrobin Delays Sexual Development and Alters Reproduction in Zebrafish ( Danio rerio).
Environmental science & technology. 53(3):1672-1679 [DOI] 10.1021/acs.est.8b05829. [PMID] 30615409.
2019
Parental exposure to azoxystrobin causes developmental effects and disrupts gene expression in F1 embryonic zebrafish (Danio rerio).
The Science of the total environment. 646:595-605 [DOI] 10.1016/j.scitotenv.2018.07.331. [PMID] 30059920.
2019
Profiling the rainbow trout hepatic miRNAome under diet-induced hyperglycemia.
Physiological genomics. 51(9):411-431 [DOI] 10.1152/physiolgenomics.00032.2019. [PMID] 31282806.
2019
Regenerative Adaptation to Electrochemical Perturbation in Planaria: A Molecular Analysis of Physiological Plasticity.
iScience. 22:147-165 [DOI] 10.1016/j.isci.2019.11.014. [PMID] 31765995.
2019
Single-walled carbon nanotubes repress viral-induced defense pathways through oxidative stress.
Nanotoxicology. 13(9):1176-1196 [DOI] 10.1080/17435390.2019.1645903. [PMID] 31328592.
2019
Social status regulates the hepatic miRNAome in rainbow trout: Implications for posttranscriptional regulation of metabolic pathways.
PloS one. 14(6) [DOI] 10.1371/journal.pone.0217978. [PMID] 31194802.
2019
Special issue on aquaculture: New opportunities to address global food supply for comparative biochemistry and physiology.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 233:1-3 [DOI] 10.1016/j.cbpb.2019.03.005. [PMID] 30878485.
2019
Sub-lethal effects of the triazole fungicide propiconazole on zebrafish (Danio rerio) development, oxidative respiration, and larval locomotor activity.
Neurotoxicology and teratology. 74 [DOI] 10.1016/j.ntt.2019.106809. [PMID] 31129159.
2019
Tebuconazole reduces basal oxidative respiration and promotes anxiolytic responses and hypoactivity in early-staged zebrafish (Danio rerio).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 217:87-97 [DOI] 10.1016/j.cbpc.2018.11.017. [PMID] 30500453.
2019
The effects of acute and repeated methylenedioxypyrovalerone (MDPV) administration on striatal transcriptome networks in male long evans rats.
Neuroscience letters. 712 [DOI] 10.1016/j.neulet.2019.134499. [PMID] 31536752.
2019
The psychoactive cathinone derivative pyrovalerone alters locomotor activity and decreases dopamine receptor expression in zebrafish (Danio rerio).
Brain and behavior. 9(11) [DOI] 10.1002/brb3.1420. [PMID] 31625691.
2019
Transcriptome analysis reveals benzotriazole ultraviolet stabilizers regulate networks related to inflammation in juvenile zebrafish (Danio rerio) brain.
Environmental toxicology. 34(2):112-122 [DOI] 10.1002/tox.22663. [PMID] 30315675.
2019
Transcriptome Profiling in Larval Fathead Minnow Exposed to Commercial Naphthenic Acids and Extracts from Fresh and Aged Oil Sands Process-Affected Water
Environmental Science & Technology. 53(17):10435-10444 [DOI] 10.1021/acs.est.9b01493.
2018
Are we closer to the vision? A proposed framework for incorporating omics into environmental assessments.
Environmental toxicology and pharmacology. 59:87-93 [DOI] 10.1016/j.etap.2018.03.005. [PMID] 29549817.
2018
Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish (Danio rerio).
Neurotoxicology and teratology. 70:18-27 [DOI] 10.1016/j.ntt.2018.10.001. [PMID] 30290195.
2018
Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb.
Cell reports. 25(6):1593-1609.e7 [DOI] 10.1016/j.celrep.2018.10.010. [PMID] 30404012.
2018
Butyrate regulates inflammatory cytokine expression without affecting oxidative respiration in primary astrocytes from spontaneously hypertensive rats.
Physiological reports. 6(14) [DOI] 10.14814/phy2.13732. [PMID] 30039527.
2018
Comprehensive assessment of shockwave intensity: Transcriptomic biomarker discovery for primary blast-induced mild traumatic brain injury using the mammalian hair follicle.
Brain injury. 32(1):123-134 [DOI] 10.1080/02699052.2017.1342000. [PMID] 29157017.
2018
Cu Promoted Hydrotalcite-Based Nial Mixed Oxides in Adsoption and Oxidation of So2 Reaction: Experimental and Theoretical Study
Separation and Purification Technology. 207:231-239 [DOI] 10.1016/j.seppur.2018.06.034.
2018
Domperidone upregulates dopamine receptor expression and stimulates locomotor activity in larval zebrafish (Danio rerio).
Genes, brain, and behavior. 17(4) [DOI] 10.1111/gbb.12460. [PMID] 29377542.
2018
Elucidating Conserved Transcriptional Networks Underlying Pesticide Exposure and Parkinson’s Disease: A Focus on Chemicals of Epidemiological Relevance.
Frontiers in genetics. 9 [DOI] 10.3389/fgene.2018.00701. [PMID] 30740124.
2018
Environmental toxicology and omics: A question of sex.
Journal of proteomics. 172:152-164 [DOI] 10.1016/j.jprot.2017.09.010. [PMID] 29037750.
2018
Environmental toxicology and omics: A question of sex.
Journal of proteomics. 172:152-164 [DOI] 10.1016/j.jprot.2017.09.010. [PMID] 29037750.
2018
Environmentally relevant concentrations of carbamazepine induce liver histopathological changes and a gender-specific response in hepatic proteome of Chinese rare minnows (Gobiocypris rarus).
Environmental pollution (Barking, Essex : 1987). 243(Pt A):480-491 [DOI] 10.1016/j.envpol.2018.09.009. [PMID] 30216880.
2018
Fluazinam impairs oxidative phosphorylation and induces hyper/hypo-activity in a dose specific manner in zebrafish larvae.
Chemosphere. 210:633-644 [DOI] 10.1016/j.chemosphere.2018.07.056. [PMID] 30031347.
2018
High-throughput assessment of oxidative respiration in fish embryos: Advancing adverse outcome pathways for mitochondrial dysfunction.
Aquatic toxicology (Amsterdam, Netherlands). 199:162-173 [DOI] 10.1016/j.aquatox.2018.03.031. [PMID] 29631217.
2018
In Silico Computational Transcriptomics Reveals Novel Endocrine Disruptors in Largemouth Bass ( Micropterus salmoides).
Environmental science & technology. 52(13):7553-7565 [DOI] 10.1021/acs.est.8b02805. [PMID] 29878769.
2018
Mitochondrial bioenergetics and locomotor activity are altered in zebrafish (Danio rerio) after exposure to the bipyridylium herbicide diquat.
Toxicology letters. 283:13-20 [DOI] 10.1016/j.toxlet.2017.10.022. [PMID] 29100808.
2018
Paraquat affects mitochondrial bioenergetics, dopamine system expression, and locomotor activity in zebrafish (Danio rerio).
Chemosphere. 191:106-117 [DOI] 10.1016/j.chemosphere.2017.10.032. [PMID] 29031050.
2018
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene.
Aquatic toxicology (Amsterdam, Netherlands). 199:90-102 [DOI] 10.1016/j.aquatox.2018.03.027. [PMID] 29621674.
2018
Part B: Morphometric and transcriptomic responses to sub-chronic exposure to the polycyclic aromatic hydrocarbon phenanthrene in the fathead minnow (Pimephales promelas).
Aquatic toxicology (Amsterdam, Netherlands). 199:77-89 [DOI] 10.1016/j.aquatox.2018.03.026. [PMID] 29621673.
2018
Reprint of: Environmental toxicology and omics: A question of sex.
Journal of proteomics. [DOI] 10.1016/j.jprot.2018.03.018. [PMID] 29650353.
2018
Rising Level of Arsenic in Water and Fodder: a Growing Threat to Livestock and Human Populations in Pakistan
Toxin Reviews. 37(3):171-181 [DOI] 10.1080/15569543.2017.1348360.
2018
Secretoneurin A Directly Regulates the Proteome of Goldfish Radial Glial Cells In Vitro.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00068. [PMID] 29559953.
2018
The gut microbiome and aquatic toxicology: An emerging concept for environmental health.
Environmental toxicology and chemistry. 37(11):2758-2775 [DOI] 10.1002/etc.4249. [PMID] 30094867.
2018
Toward an adverse outcome pathway for impaired growth: Mitochondrial dysfunction impairs growth in early life stages of the fathead minnow (Pimephales promelas).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 209:46-53 [DOI] 10.1016/j.cbpc.2018.03.009. [PMID] 29625345.
2018
Toxicity of functionalized fullerene and fullerene synthesis chemicals.
Chemosphere. 207:1-9 [DOI] 10.1016/j.chemosphere.2018.05.023. [PMID] 29763761.
2018
Transgenerational hypocortisolism and behavioral disruption are induced by the antidepressant fluoxetine in male zebrafish Danio rerio.
Proceedings of the National Academy of Sciences of the United States of America. 115(52):E12435-E12442 [DOI] 10.1073/pnas.1811695115. [PMID] 30530669.
2017
Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos.
Chemosphere. 182:22-30 [DOI] 10.1016/j.chemosphere.2017.05.015. [PMID] 28486152.
2017
Bioelectric regulation of innate immune system function in regenerating and intact Xenopus laevis.
NPJ Regenerative medicine. 2 [DOI] 10.1038/s41536-017-0019-y. [PMID] 29302351.
2017
Biological responses to phenylurea herbicides in fish and amphibians: New directions for characterizing mechanisms of toxicity.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 194:9-21 [DOI] 10.1016/j.cbpc.2017.01.002. [PMID] 28109972.
2017
Computational analysis of the ToxCast estrogen receptor agonist assays to predict vitellogenin induction by chemicals in male fish.
Environmental toxicology and pharmacology. 53:177-183 [DOI] 10.1016/j.etap.2017.05.015. [PMID] 28645054.
2017
Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio).
The Journal of pharmacology and experimental therapeutics. 361(3):375-385 [DOI] 10.1124/jpet.116.239806. [PMID] 28385952.
2017
Dieldrin-induced neurotoxicity involves impaired mitochondrial bioenergetics and an endoplasmic reticulum stress response in rat dopaminergic cells.
Neurotoxicology. 63:1-12 [DOI] 10.1016/j.neuro.2017.08.007. [PMID] 28844784.
2017
Differential transcriptome regulation by 3,5-T2 and 3′,3,5-T3 in brain and liver uncovers novel roles for thyroid hormones in tilapia.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-14913-9. [PMID] 29118400.
2017
Discriminating modes of toxic action in mice using toxicity in BALB/c mouse fibroblast (3T3) cells.
Chemosphere. 188:73-80 [DOI] 10.1016/j.chemosphere.2017.08.135. [PMID] 28869848.
2017
Estrogen-responsive gene networks in the teleost liver: What are the key molecular indicators?
Environmental toxicology and pharmacology. 56:366-374 [DOI] 10.1016/j.etap.2017.10.012. [PMID] 29126055.
2017
Exposure to Deepwater Horizon oil and Corexit 9500 at low concentrations induces transcriptional changes and alters immune transcriptional pathways in sheepshead minnows.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 23:8-16 [DOI] 10.1016/j.cbd.2017.05.001. [PMID] 28578262.
2017
Histopathological and proteomic responses in male Chinese rare minnow (Gobiocypris rarus) indicate hepatotoxicity following benzotriazole exposure.
Environmental pollution (Barking, Essex : 1987). 229:459-469 [DOI] 10.1016/j.envpol.2017.06.013. [PMID] 28624627.
2017
How consistent are we? Interlaboratory comparison study in fathead minnows using the model estrogen 17α-ethinylestradiol to develop recommendations for environmental transcriptomics.
Environmental toxicology and chemistry. 36(10):2614-2623 [DOI] 10.1002/etc.3799. [PMID] 28316117.
2017
Molecular networks related to the immune system and mitochondria are targets for the pesticide dieldrin in the zebrafish (Danio rerio) central nervous system.
Journal of proteomics. 157:71-82 [DOI] 10.1016/j.jprot.2017.02.003. [PMID] 28192238.
2017
Physiological and molecular responses of juvenile shortnose sturgeon (Acipenser brevirostrum) to thermal stress.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 203:314-321 [DOI] 10.1016/j.cbpa.2016.10.009. [PMID] 27777016.
2017
Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval zebrafish (Danio rerio).
Toxicology and applied pharmacology. 327:30-38 [DOI] 10.1016/j.taap.2017.04.024. [PMID] 28450151.
2017
Relationship between acute and chronic toxicity for prevalent organic pollutants in Vibrio fischeri based upon chemical mode of action.
Journal of hazardous materials. 338:458-465 [DOI] 10.1016/j.jhazmat.2017.05.058. [PMID] 28599262.
2017
Response of oxidative stress transcripts in the brain of wild yellow perch (Perca flavescens) exposed to an environmental gradient of methylmercury.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 192:50-58 [DOI] 10.1016/j.cbpc.2016.12.005. [PMID] 27939725.
2017
Returning to normal? Assessing transcriptome recovery over time in male rainbow darter (Etheostoma caeruleum) liver in response to wastewater-treatment plant upgrades.
Environmental toxicology and chemistry. 36(8):2108-2122 [DOI] 10.1002/etc.3741. [PMID] 28106290.
2017
Secretoneurin A regulates neurogenic and inflammatory transcriptional networks in goldfish (Carassius auratus) radial glia.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-14930-8. [PMID] 29097753.
2017
Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon.
Frontiers in physiology. 8 [DOI] 10.3389/fphys.2017.00220. [PMID] 28446880.
2017
Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses.
PloS one. 12(8) [DOI] 10.1371/journal.pone.0182930. [PMID] 28793334.
2017
The legacy pesticide dieldrin acts as a teratogen and alters the expression of dopamine transporter and dopamine receptor 2a in zebrafish (Danio rerio) embryos.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 194:37-47 [DOI] 10.1016/j.cbpc.2017.01.010. [PMID] 28163252.
2017
The pesticide dieldrin disrupts proteins related to oxidative respiration and mitochondrial stress in the central nervous system
Data in brief. 11:628-633 [DOI] 10.1016/j.dib.2017.03.008. [PMID] 28367483.
2017
Transcriptional networks in rodent models support a role for gut-brain communication in neurogenic hypertension: a review of the evidence.
Physiological genomics. 49(7):327-338 [DOI] 10.1152/physiolgenomics.00010.2017. [PMID] 28550087.
2017
Tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio) embryos/larvae at environmentally relevant levels.
Chemosphere. 189:498-506 [DOI] 10.1016/j.chemosphere.2017.09.093. [PMID] 28961535.
2016
Adsorption Performance of So2 Over Znal2O4 Nanospheres
Journal of Industrial and Engineering Chemistry. 41:151-157 [DOI] 10.1016/j.jiec.2016.07.019.
2016
Application of Molecular Endpoints in Early Life Stage Salmonid Environmental Biomonitoring
Aquatic toxicology (Amsterdam, Netherlands). 173:178-191 [DOI] 10.1016/j.aquatox.2016.01.006. [PMID] 26874677.
2016
Brain quantitative proteomic responses reveal new insight of benzotriazole neurotoxicity in female Chinese rare minnow (Gobiocypris rarus).
Aquatic toxicology (Amsterdam, Netherlands). 181:67-75 [DOI] 10.1016/j.aquatox.2016.10.030. [PMID] 27816759.
2016
Characterizing Transcriptional Networks in Male Rainbow Darter (Etheostoma Caeruleum) That Regulate Testis Development Over a Complete Reproductive Cycle
PLoS One. 11(11) [DOI] 10.1371/journal.pone.0164722. [PMID] 27861489.
2016
Determining the mode of action of anti-mycobacterial C17 diyne natural products using expression profiling: evidence for fatty acid biosynthesis inhibition.
BMC genomics. 17(1) [DOI] 10.1186/s12864-016-2949-y. [PMID] 27514659.
2016
Developmental profiles and expression of the DNA methyltransferase genes in the fathead minnow (Pimephales promelas) following exposure to di-2-ethylhexyl phthalate.
Fish physiology and biochemistry. 42(1):7-18 [DOI] 10.1007/s10695-015-0112-3. [PMID] 26251286.
2016
Dietary selenium disrupts hepatic triglyceride stores and transcriptional networks associated with growth and Notch signaling in juvenile rainbow trout.
Aquatic toxicology (Amsterdam, Netherlands). 180:103-114 [DOI] 10.1016/j.aquatox.2016.09.014. [PMID] 27694045.
2016
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation.
Regeneration (Oxford, England). 3(1):3-25 [DOI] 10.1002/reg2.48. [PMID] 27499876.
2016
Hepatic gene expression profiling in zebrafish (Danio rerio) exposed to the fungicide chlorothalonil.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:102-111 [DOI] 10.1016/j.cbd.2016.04.004. [PMID] 27264782.
2016
High contaminant loads in Lake Apopka’s riparian wetland disrupt gene networks involved in reproduction and immune function in largemouth bass.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:140-150 [DOI] 10.1016/j.cbd.2016.06.003. [PMID] 27397556.
2016
Lethal and sublethal effects of phthalate diesters in Silurana tropicalis larvae.
Environmental toxicology and chemistry. 35(10):2511-2522 [DOI] 10.1002/etc.3413. [PMID] 26924002.
2016
Loss of bone marrow adrenergic beta 1 and 2 receptors modifies transcriptional networks, reduces circulating inflammatory factors, and regulates blood pressure.
Physiological genomics. 48(7):526-36 [DOI] 10.1152/physiolgenomics.00039.2016. [PMID] 27235450.
2016
Molecular impacts of perfluorinated chemicals (PFASs) in the liver and testis of male largemouth bass (Micropterus salmoides) in Minnesota Lakes.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:129-139 [DOI] 10.1016/j.cbd.2016.02.001. [PMID] 26907229.
2016
Proteomic profiling reveals dopaminergic regulation of progenitor cell functions of goldfish radial glial cells in vitro.
Journal of proteomics. 144:123-32 [DOI] 10.1016/j.jprot.2016.05.003. [PMID] 27185549.
2016
Spotlight on environmental omics and toxicology: a long way in a short time.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:97-101 [DOI] 10.1016/j.cbd.2016.06.010. [PMID] 27398986.
2016
The influence of breeding strategy, reproductive stage, and tissue type on transcript variability in fish.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:151-158 [DOI] 10.1016/j.cbd.2016.05.005. [PMID] 27325421.
2016
Transcriptional networks associated with 5-alpha-dihydrotestosterone in the fathead minnow (Pimephales promelas) ovary.
General and comparative endocrinology. 225:23-32 [DOI] 10.1016/j.ygcen.2015.09.005. [PMID] 26344943.
2016
Transcriptional networks associated with the immune system are disrupted by organochlorine pesticides in largemouth bass (Micropterus salmoides) ovary.
Aquatic toxicology (Amsterdam, Netherlands). 177:405-16 [DOI] 10.1016/j.aquatox.2016.06.009. [PMID] 27391359.
2015
Omics for aquatic ecotoxicology: control of extraneous variability to enhance the analysis of environmental effects.
Environmental toxicology and chemistry. 34(8):1693-704 [DOI] 10.1002/etc.3002. [PMID] 25827364.
2015
Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation.
Science signaling. 8(397) [DOI] 10.1126/scisignal.aac6609. [PMID] 26443706.
2015
Transcript variability and physiological correlates in the fathead minnow ovary: Implications for sample size, and experimental power.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 187:22-30 [DOI] 10.1016/j.cbpb.2015.04.013. [PMID] 25956319.
2015
Transcriptomic Responses During Early Development Following Arsenic Exposure in Western Clawed Frogs, Silurana tropicalis.
Toxicological sciences : an official journal of the Society of Toxicology. 148(2):603-17 [DOI] 10.1093/toxsci/kfv207. [PMID] 26427749.
2015
Transcripts involved in steroid biosynthesis and steroid receptor signaling are expressed early in development in the fathead minnow (Pimephales promelas).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 182:64-72 [DOI] 10.1016/j.cbpb.2014.12.003. [PMID] 25546055.
2015
Using molecular biomarkers and traditional morphometric measurements to assess the health of slimy sculpin (Cottus cognatus) from streams with elevated selenium in North-Eastern British Columbia.
Environmental toxicology and chemistry. 34(10):2335-46 [DOI] 10.1002/etc.3064. [PMID] 25982233.
2015
Whole organism responses and intersex severity in rainbow darter (Etheostoma caeruleum) following exposures to municipal wastewater in the Grand River basin, ON, Canada. Part A.
Aquatic toxicology (Amsterdam, Netherlands). 159:290-301 [DOI] 10.1016/j.aquatox.2014.11.023. [PMID] 25543172.
2014
Current concepts in neuroendocrine disruption.
General and comparative endocrinology. 203:158-173 [DOI] 10.1016/j.ygcen.2014.02.005. [PMID] 24530523.
2014
Dietary exposure of 17-alpha ethinylestradiol modulates physiological endpoints and gene signaling pathways in female largemouth bass (Micropterus salmoides).
Aquatic toxicology (Amsterdam, Netherlands). 156:148-60 [DOI] 10.1016/j.aquatox.2014.08.008. [PMID] 25203422.
2014
Effects of dechlorane plus on the hepatic proteome of juvenile Chinese sturgeon (Acipenser sinensis).
Aquatic toxicology (Amsterdam, Netherlands). 148:83-91 [DOI] 10.1016/j.aquatox.2014.01.003. [PMID] 24463492.
2014
Metabolic consequences of microRNA-122 inhibition in rainbow trout, Oncorhynchus mykiss.
BMC genomics. 15 [DOI] 10.1186/1471-2164-15-70. [PMID] 24467738.
2014
Methylmercury-induced changes in gene transcription associated with neuroendocrine disruption in largemouth bass (Micropterus salmoides).
General and comparative endocrinology. 203:215-224 [DOI] 10.1016/j.ygcen.2014.03.029. [PMID] 24694518.
2014
Molecular responses to 17β-estradiol in early life stage salmonids.
General and comparative endocrinology. 203:203-14 [DOI] 10.1016/j.ygcen.2014.03.023. [PMID] 24698784.
2014
Molecular signatures in rainbow darter (Etheostoma caeruleum) inhabiting an urbanized river reach receiving wastewater effluents.
Aquatic toxicology (Amsterdam, Netherlands). 148:211-20 [DOI] 10.1016/j.aquatox.2014.01.010. [PMID] 24513783.
2014
Progesterone increases ex vivo testosterone production and decreases the expression of progestin receptors and steroidogenic enzymes in the fathead minnow (Pimephales promelas) ovary.
General and comparative endocrinology. 199:16-25 [DOI] 10.1016/j.ygcen.2014.01.004. [PMID] 24462459.
2014
Pyruvate carboxylase as a sensitive protein biomarker for exogenous steroid chemicals.
Environmental pollution (Barking, Essex : 1987). 189:184-93 [DOI] 10.1016/j.envpol.2014.03.006. [PMID] 24681510.
2014
Reprint of “Current perspectives on the androgen 5 alpha-dihydrotestosterone (DHT) and 5 alpha-reductases in teleost fishes and amphibians”.
General and comparative endocrinology. 203:10-20 [DOI] 10.1016/j.ygcen.2014.06.011. [PMID] 24954687.
2014
Sediment contaminated with the Azo Dye disperse yellow 7 alters cellular stress- and androgen-related transcription in Silurana tropicalis larvae.
Environmental science & technology. 48(5):2952-61 [DOI] 10.1021/es500263x. [PMID] 24467182.
2014
Transcriptional profiling in rat hair follicles following simulated Blast insult: a new diagnostic tool for traumatic brain injury.
PloS one. 9(8) [DOI] 10.1371/journal.pone.0104518. [PMID] 25136963.
2014
Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride.
General and comparative endocrinology. 203:137-45 [DOI] 10.1016/j.ygcen.2014.01.018. [PMID] 24530632.
2014
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone.
General and comparative endocrinology. 203:106-19 [DOI] 10.1016/j.ygcen.2014.01.003. [PMID] 24447443.
2013
Assessing gene network stability and individual variability in the fathead minnow (Pimephales promelas) transcriptome.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 8(4):283-91 [DOI] 10.1016/j.cbd.2013.08.002. [PMID] 24036207.
2013
Classifying chemical mode of action using gene networks and machine learning: a case study with the herbicide linuron.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 8(4):263-74 [DOI] 10.1016/j.cbd.2013.08.001. [PMID] 24013142.
2013
Current perspectives on the androgen 5 alpha-dihydrotestosterone (DHT) and 5 alpha-reductases in teleost fishes and amphibians.
General and comparative endocrinology. 194:264-74 [DOI] 10.1016/j.ygcen.2013.09.019. [PMID] 24095809.
2013
Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides).
PloS one. 8(3) [DOI] 10.1371/journal.pone.0059093. [PMID] 23527095.
2013
Gene expression profiling in the ovary of Queen conch (Strombus gigas) exposed to environments with high tributyltin in the British Virgin Islands.
The Science of the total environment. 449:52-62 [DOI] 10.1016/j.scitotenv.2013.01.028. [PMID] 23410894.
2013
Genome wide analysis of Silurana (Xenopus) tropicalis development reveals dynamic expression using network enrichment analysis.
Mechanisms of development. 130(4-5):304-22 [DOI] 10.1016/j.mod.2012.12.002. [PMID] 23295496.
2013
Intersex in teleost fish: are we distinguishing endocrine disruption from natural phenomena?
General and comparative endocrinology. 192:25-35 [DOI] 10.1016/j.ygcen.2013.04.005. [PMID] 23603430.
2013
Protein targets of acrylamide adduct formation in cultured rat dopaminergic cells.
Toxicology letters. 219(3):279-87 [DOI] 10.1016/j.toxlet.2013.03.031. [PMID] 23566896.
2013
Proteome analysis of the fathead minnow (Pimephales promelas) reproductive testes.
Journal of proteomics. 79:28-42 [DOI] 10.1016/j.jprot.2012.11.023. [PMID] 23234800.
2013
Sexually dimorphic transcriptomic responses in the teleostean hypothalamus: a case study with the organochlorine pesticide dieldrin.
Neurotoxicology. 34:105-17 [DOI] 10.1016/j.neuro.2012.09.012. [PMID] 23041725.
2013
The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus).
Aquatic toxicology (Amsterdam, Netherlands). 134-135:34-46 [DOI] 10.1016/j.aquatox.2013.03.001. [PMID] 23542652.
2013
The effects of the urea-based herbicide linuron on reproductive endpoints in the fathead minnow (Pimephales promelas).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 157(1):24-32 [DOI] 10.1016/j.cbpc.2012.09.001. [PMID] 22982884.
2013
Transcriptional signature of progesterone in the fathead minnow ovary (Pimephales promelas).
General and comparative endocrinology. 192:159-69 [DOI] 10.1016/j.ygcen.2013.06.008. [PMID] 23796460.
2013
Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis.
General and comparative endocrinology. 192:115-25 [DOI] 10.1016/j.ygcen.2013.04.033. [PMID] 23665105.
2013
Using Omics Technologies To Unravel Mechanisms of Toxicity From Endocrine Disruptors in Aquatic Species
Toxicology Letters. 221 [DOI] 10.1016/j.toxlet.2013.06.227.
2013
γ-Amino-butyric acid (GABA) receptor subunit and transporter expression in the gonad and liver of the fathead minnow (Pimephales promelas).
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 166(1):119-27 [DOI] 10.1016/j.cbpa.2013.05.005. [PMID] 23672824.
2012
Advancing the Omics in aquatic toxicology: SETAC North America 31st Annual Meeting.
Ecotoxicology and environmental safety. 76(2):1-2 [DOI] 10.1016/j.ecoenv.2011.11.001. [PMID] 22114953.
2012
Applications for next-generation sequencing in fish ecotoxicogenomics.
Frontiers in genetics. 3 [DOI] 10.3389/fgene.2012.00062. [PMID] 22539934.
2012
DIGE and iTRAQ as biomarker discovery tools in aquatic toxicology.
Ecotoxicology and environmental safety. 76(2):3-10 [DOI] 10.1016/j.ecoenv.2011.09.020. [PMID] 22056798.
2012
Exploring androgen-regulated pathways in teleost fish using transcriptomics and proteomics.
Integrative and comparative biology. 52(5):695-704 [DOI] 10.1093/icb/ics072. [PMID] 22596056.
2012
Hepatic protein expression networks associated with masculinization in the female fathead minnow (Pimephales promelas).
Journal of proteome research. 11(8):4147-61 [DOI] 10.1021/pr3002468. [PMID] 22734619.
2012
Is secretoneurin a new hormone?
General and comparative endocrinology. 175(1):10-8 [DOI] 10.1016/j.ygcen.2011.10.008. [PMID] 22036841.
2012
Meta-type analysis of dopaminergic effects on gene expression in the neuroendocrine brain of female goldfish.
Frontiers in endocrinology. 3 [DOI] 10.3389/fendo.2012.00130. [PMID] 23130016.
2012
Proteomic expression patterns in fathead minnows exposed to trenbolone and flutamide
Integrative and Comparative Biology. 52(1)
2012
PROTEOMICS AS A TOOL TO STUDY NEUROTOXICITY IN FISH
Integrative and Comparative Biology. 52(1)
2012
Quantitative proteomics in teleost fish: insights and challenges for neuroendocrine and neurotoxicology research.
General and comparative endocrinology. 176(3):314-20 [DOI] 10.1016/j.ygcen.2011.12.006. [PMID] 22202605.
2011
Cloning and expression of the translocator protein (18 kDa), voltage-dependent anion channel, and diazepam binding inhibitor in the gonad of largemouth bass (Micropterus salmoides) across the reproductive cycle.
General and comparative endocrinology. 173(1):86-95 [DOI] 10.1016/j.ygcen.2011.04.027. [PMID] 21600210.
2011
Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury.
Environmental toxicology and chemistry. 30(2):301-8 [DOI] 10.1002/etc.409. [PMID] 21082716.
2011
Methoxychlor affects multiple hormone signaling pathways in the largemouth bass (Micropterus salmoides) liver.
Aquatic toxicology (Amsterdam, Netherlands). 101(3-4):483-92 [DOI] 10.1016/j.aquatox.2010.12.002. [PMID] 21276474.
2011
Molecular mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by α,β-unsaturated carbonyl derivatives.
Chemical research in toxicology. 24(12):2302-11 [DOI] 10.1021/tx200437y. [PMID] 22084934.
2011
Omics in aquatic toxicology: not just another microarray.
Environmental toxicology and chemistry. 30(2):263-4 [DOI] 10.1002/etc.428. [PMID] 21229596.
2010
Effects of acute dieldrin exposure on neurotransmitters and global gene transcription in largemouth bass (Micropterus salmoides) hypothalamus.
Neurotoxicology. 31(4):356-66 [DOI] 10.1016/j.neuro.2010.04.008. [PMID] 20438755.
2010
Environmentally relevant exposure to 17alpha-ethinylestradiol affects the telencephalic proteome of male fathead minnows
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2010
Environmentally relevant exposure to 17alpha-ethinylestradiol affects the telencephalic proteome of male fathead minnows.
Aquatic toxicology (Amsterdam, Netherlands). 98(4):344-53 [DOI] 10.1016/j.aquatox.2010.03.007. [PMID] 20381887.
2010
Genomic and proteomic responses to environmentally relevant exposures to dieldrin: indicators of neurodegeneration?
Toxicological sciences : an official journal of the Society of Toxicology. 117(1):190-9 [DOI] 10.1093/toxsci/kfq192. [PMID] 20584760.
2010
Rapid dopaminergic modulation of the fish hypothalamic transcriptome and proteome
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2010
Rapid dopaminergic modulation of the fish hypothalamic transcriptome and proteome.
PloS one. 5(8) [DOI] 10.1371/journal.pone.0012338. [PMID] 20808832.
2010
Sex- and tissue-specific effects of waterborne estrogen on estrogen receptor subtypes and E2-mediated gene expression in the reproductive axis of goldfish.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 156(1):92-101 [DOI] 10.1016/j.cbpa.2010.01.001. [PMID] 20060486.
2009
Aquatic contaminants alter genes involved in neurotransmitter synthesis and gonadotropin release in largemouth bass
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2009
Aquatic contaminants alter genes involved in neurotransmitter synthesis and gonadotropin release in largemouth bass.
Aquatic toxicology (Amsterdam, Netherlands). 95(1):1-9 [DOI] 10.1016/j.aquatox.2009.06.009. [PMID] 19781795.
2009
Defining global neuroendocrine gene expression patterns associated with reproductive seasonality in fish.
PloS one. 4(6) [DOI] 10.1371/journal.pone.0005816. [PMID] 19503831.
2009
Fish endocrinology meets functional genomics: what exactly is the message?
General and comparative endocrinology. 164(2-3):132-4 [DOI] 10.1016/j.ygcen.2009.05.013. [PMID] 19481084.
2009
Group III metabotropic glutamate receptors (mGluRs) modulate transmission of gustatory inputs in the brain stem.
Journal of neurophysiology. 102(1):192-202 [DOI] 10.1152/jn.00135.2009. [PMID] 19369363.
2009
Profiling neuroendocrine gene expression changes following fadrozole-induced estrogen decline in the female goldfish.
Physiological genomics. 38(3):351-61 [DOI] 10.1152/physiolgenomics.00051.2009. [PMID] 19509080.
2009
Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).
Journal of proteome research. 8(5):2186-200 [DOI] 10.1021/pr800627n. [PMID] 19267455.
2009
Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephalus promelas)
Journal of Proteome Research. (8):2186-2200
2009
Seasonal relationship between gonadotropin, growth hormone, and estrogen receptor mRNA expression in the pituitary gland of largemouth bass.
General and comparative endocrinology. 163(3):306-17 [DOI] 10.1016/j.ygcen.2009.04.028. [PMID] 19416730.
2009
Sources Fate and Effects of Engineered Nanomaterials in the Aquatic Environment
.
2009
Towards functional genomics in fish using quantitative proteomics.
General and comparative endocrinology. 164(2-3):135-41 [DOI] 10.1016/j.ygcen.2009.01.023. [PMID] 19523377.
2008
Auto-regulation of estrogen receptor subtypes and gene expression profiling of 17beta-estradiol action in the neuroendocrine axis of male goldfish.
Molecular and cellular endocrinology. 283(1-2):38-48 [PMID] 18083300.
View on: PubMed
2008
Chronic exposure of Rana pipiens tadpoles to UVB radiation and the estrogenic chemical 4-tert-octylphenol.
Journal of toxicology and environmental health. Part A. 71(2):134-44 [PMID] 18080904.
View on: PubMed
2008
Effects of fluoxetine on the reproductive axis of female goldfish (Carassius auratus).
Physiological genomics. 35(3):273-82 [DOI] 10.1152/physiolgenomics.90263.2008. [PMID] 18765858.
2008
The goldfish (Carassius auratus) as a model for neuroendocrine signaling.
Molecular and cellular endocrinology. 293(1-2):43-56 [DOI] 10.1016/j.mce.2008.06.017. [PMID] 18657592.
2008
Using generalized procrustes analysis (GPA) for normalization of cDNA microarray data.
BMC bioinformatics. 9 [DOI] 10.1186/1471-2105-9-25. [PMID] 18199333.
2007
Early evolution of ionotropic GABA receptors and selective regimes acting on the mammalian-specific theta and epsilon subunits.
PloS one. 2(9) [PMID] 17878929.
View on: PubMed
2007
Glutamic acid decarboxylase 65, 67, and GABA-transaminase mRNA expression and total enzyme activity in the goldfish (Carassius auratus) brain.
Brain research. 1147:154-66 [PMID] 17362888.
View on: PubMed
2007
Microarray analysis in the zebrafish (Danio rerio) liver and telencephalon after exposure to low concentration of 17alpha-ethinylestradiol.
Aquatic toxicology (Amsterdam, Netherlands). 84(1):38-49 [PMID] 17606305.
View on: PubMed
2007
The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain.
Journal of neuroendocrinology. 19(5):390-6 [PMID] 17425614.
View on: PubMed
2006
Gene expression profiling in the neuroendocrine brain of male goldfish (Carassius auratus) exposed to 17alpha-ethinylestradiol.
Physiological genomics. 27(3):328-36 [PMID] 16954407.
View on: PubMed
2006
SANTA domain: a novel conserved protein module in Eukaryota with potential involvement in chromatin regulation.
Bioinformatics (Oxford, England). 22(20):2459-62 [PMID] 16877755.
View on: PubMed
2005
GABAergic modulation of the expression of genes involved in GABA synaptic transmission and stress in the hypothalamus and telencephalon of the female goldfish (Carassius auratus).
Journal of neuroendocrinology. 17(5):269-75 [PMID] 15869561.
View on: PubMed
2004
Differential expression of the methyl-cytosine binding protein 2 gene in embryonic and adult brain of zebrafish.
Brain research. Developmental brain research. 153(2):281-7 [PMID] 15527897.
View on: PubMed

Grants

Mar 2021 ACTIVE
Examining thyroid hormone synthesis feedback loops as xenobiotic target for brominated flame retardant metabolites
Role: Co-Investigator
Funding: NATL INST OF HLTH NIEHS
Feb 2021 ACTIVE
Fibroblast cell isolation and expansion and iPSC derivation in purebred Maine Coon and Ragdoll cats
Role: Other
Funding: AM COLL OF VET INTERNAL MED via NESTLE PURINA PETCARE COMPANY
Jan 2021 ACTIVE
D21CA-042: A CRISPR/Cas9 homology-independent targeted insertion (HITI) strategy to advance gene therapy in canine iPSC-derived cardiomyocytes
Role: Principal Investigator
Funding: MORRIS ANIMAL FOU
Sep 2020 ACTIVE
Development of HITI CRISPR gene therapy for dilated cardiomyopathy in a canine model
Role: Co-Investigator
Funding: SAREPTA THERAPEUTICS
Jul 2020 ACTIVE
OR-DRPD-ROF2020: A humanized peroxisome proliferator activated receptor alpha (PPARa) zebrafish: A new transgenic model for obesogenic chemical screening
Role: Co-Investigator
Funding: UF RESEARCH
May 2020 ACTIVE
Development of a feline hyperthyroid cell line
Role: Principal Investigator
Funding: ROYAL CANIN USA, INC
Jul 2019 ACTIVE
Pluripotent Stem Cell Derived-Cardiomyocytes for Metabolic Profiling in a Genetic Canine Model of Heart Failure
Role: Co-Investigator
Funding: AMER COL OF VET INTERN MED FOU
May 2019 – May 2020
Mitochondria as a therapeutic target in iPSC neurons containing chromosome deletion Xq27-q28
Role: Principal Investigator
Funding: XTRAORDINARY JOY FOUNDATION
Dec 2018 ACTIVE
Gut-brain axis: functional link between microbial metabolites and neurogenic hypertension
Role: Principal Investigator
Funding: NATL CTR FOR COMPLEM AND INTEGRATIVE HLT
Oct 2018 ACTIVE
Increasing Understanding of and Developing Management Strategies for Edwardsiella ictaluri in Ornamental Fish
Role: Co-Investigator
Funding: USDA NIFA MS ST UNIV S REG AQUACLTR CTR via US DEPT OF AG NATL INST OF FOOD AND AG
Sep 2017 – Aug 2019
High salt diet potentiation of AngII HTN : Novel role for Th17 cell infiltration into the PVN
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2016 – Jun 2018
OBESOGENS – environmental chemicals as obesogens
Role: Principal Investigator
Funding: MASARYKOVA UNIVERZITA via EUROPEAN UNION
Sep 2012 ACTIVE
DSR Matching Support – Support for NSF Fellowship
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS

Teaching Profile

Courses Taught
2014,2016-2020,2020
VME6603 Advanced Toxicology
2014-2020
VEM5172 Veterinary Toxicology
2015-2021
VME6905 Problems in Veterinary Medical Sciences
2014-2021
VEM5176 Poisonous Plants
2019
WIS4934 Topics in Wildlife Ecology and Conservation
2019
WIS6934 Topics in Wildlife Ecology and Conservation
2018-2019
VEM5991 Clkship Indiv Invest
2016-2018
VEM5008 Personal/Prof Develop
2018
VME7980 Research for Doctoral Dissertation
2018
PHC7980 Research for Doctoral Dissertation
2018
FAS7979 Advanced Research
2018
ZOO7980 Research for Doctoral Dissertation
2014
VME6932 Seminar in Physiological Sciences
2021
BSC4910 Individual Mentored Research in Biology
2021
VME6934 Topics in Veterinary Medical Sciences

Contact Details

Phones:
Business:
(352) 294-4636
Emails:
Business:
cmartyn@ufl.edu

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IFAS

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IFAS

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