Chen Gilor,
Associate Professor, SA Internal Medicine
Department:
Small Animal Clinical Sciences
Business Phone:
(352) 392-2235
Business Email:
cgilor@ufl.edu
About Chen Gilor
I have been dedicated to improving the quality of life of diabetic cats and dogs and their humans for over 15 years. At the forefront of canine and feline diabetes research, I have published extensively on novel insulin therapies, insulin-alternatives and the pathophysiology of diabetes mellitus. My career goal is to develop diagnostic tests for prediabetes and find treatments that would delay and prevent the need for insulin therapy.
Related Links:
Accomplishments
ACVIM Resident Research Award in SAIM, Endocrinology (Mentor)
2017
·
American College of Veterinary Internal Medicine
Zoetis Animal Health Award for Research Excellence
2015
·
College of Veterinary Medicine, The Ohio State University
Virbac Animal Health 11th Annual Award for best endocrinology abstract (Mentor)
2014
·
American College of Veterinary Internal Medicine
The Ann Johnson and Wally Hoffman Resident Teaching Excellence Award
2008
·
College of Veterinary Medicine, University of Illinois at Urbana-Champaign
Dean’s List of Excellence Award
1992
·
The Faculty of Agricultural, food and environmental studies, The Hebrew University of Jerusalem, Rehovot, Israel
Dean’s List of Excellence Award
1991
·
The Faculty of Agricultural, food and environmental studies, The Hebrew University of Jerusalem, Rehovot, Israel
Teaching Profile
Courses Taught
2019-2024
VEM5306 Vet Endocrinology
2020-2022
VEM5110 Animal Systems 1
2019-2024
VEM5741 Small Animal Internal Medicine Clerkship
2019-2024
VEM5841 Adv. Small Animal Medicine Clerkship
2021,2023-2024
VEM5221 Intro Clinic Pathol
2023-2024
VEM5309 Veterinary Gastroenterology
2023
VEM5402L Introduction to Surgery Lab
2023-2024
VEM5288 Sm An Clin Pharmacol
Board Certifications
-
Diplomate, American College of Veterinary Internal MedicineACVIM
Research Profile
— Diabetes mellitus
— Obesity
— Gastrointestinal endocrinology
— Adrenal diseases
Publications
2024
A dose titration protocol for once-daily insulin glargine 300 U/mL for the treatment of diabetes mellitus in dogs.
Journal of veterinary internal medicine.
38(4):2120-2128
[DOI] 10.1111/jvim.17106.
[PMID] 38831362.
2024
Drug release profile of a novel exenatide long-term drug delivery system (OKV-119) administered to cats.
BMC veterinary research.
20(1)
[DOI] 10.1186/s12917-024-04051-6.
[PMID] 38762728.
2024
Gut microbiota promoting propionic acid production accompanies caloric restriction-induced intentional weight loss in cats.
Scientific reports.
14(1)
[DOI] 10.1038/s41598-024-62243-4.
[PMID] 38789518.
2024
Isolation of feline islets of Langerhans by selective osmotic shock produces glucose responsive islets.
Frontiers in veterinary science.
11
[DOI] 10.3389/fvets.2024.1365611.
[PMID] 38515535.
2024
Laparoscopic partial pancreatectomy of the left limb using a harmonic scalpel in nine cats.
Veterinary surgery : VS.
53(2):350-356
[DOI] 10.1111/vsu.14052.
[PMID] 38037261.
2024
Magnet-assisted endoscopic removal of ferromagnetic metallic gastric foreign bodies in 4 dogs.
Journal of veterinary internal medicine.
38(4):2348-2352
[DOI] 10.1111/jvim.17105.
[PMID] 38761024.
2024
Spontaneous remission and relapse of diabetes mellitus in a male dog.
Journal of veterinary internal medicine.
38(2):1152-1156
[DOI] 10.1111/jvim.16991.
[PMID] 38240130.
2024
The glucagon-receptor antagonist MK-3577 reduces glucagon-stimulated plasma glucose and insulin concentrations in metabolically healthy overweight cats.
Domestic animal endocrinology.
89
[DOI] 10.1016/j.domaniend.2024.106874.
[PMID] 39018655.
2023
Anemia in canine chronic kidney disease is multifactorial and associated with decreased erythroid precursor cells, gastrointestinal bleeding, and systemic inflammation.
American journal of veterinary research.
84(10):1-6
[DOI] 10.2460/ajvr.23.05.0097.
[PMID] 37586694.
2023
Assessment of the FreeStyle Libre 2 interstitial glucose monitor in hypo- and euglycemic cats.
Journal of veterinary internal medicine.
37(5):1703-1709
[DOI] 10.1111/jvim.16820.
[PMID] 37534946.
2023
Both Feline Coronavirus Serotypes 1 and 2 Infected Domestic Cats Develop Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain: Its Implication to Pan-CoV Vaccine Development.
Viruses.
15(4)
[DOI] 10.3390/v15040914.
[PMID] 37112894.
2023
Case report: Androgen-secreting adrenocortical tumors in eight cats.
Frontiers in veterinary science.
10
[DOI] 10.3389/fvets.2023.1158142.
[PMID] 37383353.
2023
Diabetes Mellitus in Cats and Dogs.
The Veterinary clinics of North America. Small animal practice.
53(3):xiii-xiv
[DOI] 10.1016/j.cvsm.2023.02.018.
[PMID] 37028830.
2023
Establishment of a feline glycated hemoglobin reference interval for a novel dried-blood-spot assay and the effects of anemia on assay results.
Veterinary clinical pathology.
52(3):531-539
[DOI] 10.1111/vcp.13257.
[PMID] 37408106.
2023
Glucose Counterregulation: Clinical Consequences of Impaired Sympathetic Responses in Diabetic Dogs and Cats.
The Veterinary clinics of North America. Small animal practice.
53(3):551-564
[DOI] 10.1016/j.cvsm.2023.01.001.
[PMID] 36898860.
2023
Gut microbiota promoting propionic acid production accompanies diet-induced intentional weight loss in cats.
Research square.
[DOI] 10.21203/rs.3.rs-3273531/v1.
[PMID] 37693421.
2023
Insulin Therapy in Small Animals, Part 1: General Principles.
The Veterinary clinics of North America. Small animal practice.
53(3):615-633
[DOI] 10.1016/j.cvsm.2023.02.002.
[PMID] 36906469.
2023
Insulin Therapy in Small Animals, Part 2: Cats.
The Veterinary clinics of North America. Small animal practice.
53(3):635-644
[DOI] 10.1016/j.cvsm.2023.02.004.
[PMID] 36906468.
2023
Insulin Therapy in Small Animals, Part 3: Dogs.
The Veterinary clinics of North America. Small animal practice.
53(3):645-656
[DOI] 10.1016/j.cvsm.2023.02.003.
[PMID] 36906466.
2023
Re-evaluation of the low-dose dexamethasone suppression test in dogs.
The Journal of small animal practice.
64(1):12-20
[DOI] 10.1111/jsap.13553.
[PMID] 36089334.
2023
Successful multimodal treatment of extreme hypertriglyceridemia in a juvenile diabetic dog.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001).
33(2):247-256
[DOI] 10.1111/vec.13275.
[PMID] 36573353.
2022
Agreeing Language in Veterinary Endocrinology (ALIVE): Diabetes mellitus – a modified Delphi-method-based system to create consensus disease definitions.
Veterinary journal (London, England : 1997).
289
[DOI] 10.1016/j.tvjl.2022.105910.
[PMID] 36182064.
2022
Characterization of clinicopathologic and abdominal ultrasound findings in dogs with glucocorticoid deficient hypoadrenocorticism.
Journal of veterinary internal medicine.
36(6):1947-1957
[DOI] 10.1111/jvim.16564.
[PMID] 36326216.
2022
Evaluation of a machine learning tool to screen for hypoadrenocorticism in dogs presenting to a teaching hospital.
Journal of veterinary internal medicine.
36(6):1942-1946
[DOI] 10.1111/jvim.16566.
[PMID] 36259689.
2022
Insulin glargine 300 U/ml for the treatment of feline diabetes mellitus.
Journal of feline medicine and surgery.
24(2):168-176
[DOI] 10.1177/1098612X211013018.
[PMID] 34009061.
2022
One hundred years of insulin: Is it time for smart?
The Journal of small animal practice.
63(9):645-660
[DOI] 10.1111/jsap.13507.
[PMID] 35560042.
2022
The effect of capromorelin on glycemic control in healthy dogs.
Domestic animal endocrinology.
81
[DOI] 10.1016/j.domaniend.2022.106732.
[PMID] 35689953.
2022
Ultra-long-acting recombinant insulin for the treatment of diabetes mellitus in dogs.
Journal of veterinary internal medicine.
36(4):1211-1219
[DOI] 10.1111/jvim.16449.
[PMID] 35621084.
2021
A novel bone marrow-sparing treatment for primary erythrocytosis in a cat: Onion powder.
Journal of veterinary internal medicine.
35(4):1977-1980
[DOI] 10.1111/jvim.16194.
[PMID] 34110655.
2021
Accuracy of a flash glucose monitoring system in cats and determination of the time lag between blood glucose and interstitial glucose concentrations.
Journal of veterinary internal medicine.
35(3):1279-1287
[DOI] 10.1111/jvim.16122.
[PMID] 33991129.
2021
An ultra-long-acting recombinant insulin for the treatment of diabetes mellitus in cats.
Journal of veterinary internal medicine.
35(5):2123-2130
[DOI] 10.1111/jvim.16150.
[PMID] 34190365.
2021
Comparison of pharmacodynamics between insulin glargine 100 U/mL and insulin glargine 300 U/mL in healthy cats.
Domestic animal endocrinology.
75
[DOI] 10.1016/j.domaniend.2020.106595.
[PMID] 33307335.
2021
Consistency of faecal scoring using two canine faecal scoring systems.
The Journal of small animal practice.
62(3):167-173
[DOI] 10.1111/jsap.13283.
[PMID] 33491796.
2021
Day-to-day variability of porcine lente, insulin glargine 300 U/mL and insulin degludec in diabetic dogs.
Journal of veterinary internal medicine.
35(5):2131-2139
[DOI] 10.1111/jvim.16178.
[PMID] 34241910.
2021
Efficacy of a micronized, nanocrystal fenofibrate formulation in treatment of hyperlipidemia in dogs.
Journal of veterinary internal medicine.
35(4):1733-1742
[DOI] 10.1111/jvim.16190.
[PMID] 34096101.
2021
Fenofibrate promotes PPARα-targeted recovery of the intestinal epithelial barrier at the host-microbe interface in dogs with diabetes mellitus.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-92966-7.
[PMID] 34188162.
2021
Safety, Tolerability, and Proof-Of-Concept Study of OKV-119, a Novel Exenatide Long-Term Drug Delivery System, in Healthy Cats.
Frontiers in veterinary science.
8
[DOI] 10.3389/fvets.2021.661546.
[PMID] 34046446.
2021
Serum trypsin-like immunoreactivity in dogs with diabetes mellitus.
Journal of veterinary internal medicine.
35(4):1713-1719
[DOI] 10.1111/jvim.16208.
[PMID] 34196025.
2021
The effect of the ghrelin-receptor agonist capromorelin on glucose metabolism in healthy cats.
Domestic animal endocrinology.
74
[DOI] 10.1016/j.domaniend.2020.106484.
[PMID] 32619812.
2020
Co-impairment of autonomic and glucagon responses to insulin-induced hypoglycemia in dogs with naturally occurring insulin-dependent diabetes mellitus.
American journal of physiology. Endocrinology and metabolism.
319(6):E1074-E1083
[DOI] 10.1152/ajpendo.00379.2020.
[PMID] 33044845.
2020
Hypocholesterolemia in cats: a multicenter retrospective study of 106 cats.
Journal of feline medicine and surgery.
22(8):768-773
[DOI] 10.1177/1098612X19886398.
[PMID] 31710272.
2020
Loss of sympathetic innervation to islets of Langerhans in canine diabetes and pancreatitis is not associated with insulitis.
Scientific reports.
10(1)
[DOI] 10.1038/s41598-020-76091-5.
[PMID] 33154408.
2020
Machine learning algorithm as a diagnostic tool for hypoadrenocorticism in dogs.
Domestic animal endocrinology.
72
[DOI] 10.1016/j.domaniend.2019.106396.
[PMID] 32006871.
2019
Comparison of pharmacodynamics and pharmacokinetics of insulin degludec and insulin glargine 300 U/mL in healthy cats.
Domestic animal endocrinology.
69:19-29
[DOI] 10.1016/j.domaniend.2019.04.001.
[PMID] 31280022.
2019
Concise Review: Canine Diabetes Mellitus as a Translational Model for Innovative Regenerative Medicine Approaches.
Stem cells translational medicine.
8(5):450-455
[DOI] 10.1002/sctm.18-0163.
[PMID] 30719867.
2019
Diagnostic utility of thoracic radiographs and abdominal ultrasound in canine immune-mediated hemolytic anemia.
The Canadian veterinary journal = La revue veterinaire canadienne.
60(10):1065-1071
[PMID] 31597991.
2019
Discussing prognosis for canine diabetes mellitus: do we have relevant data?
The Veterinary record.
185(22):689-691
[DOI] 10.1136/vr.l6719.
[PMID] 31806830.
2019
Thermogenic crosstalk occurs between adipocytes from different species.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-50628-9.
[PMID] 31645582.
2018
Effects of oral Akkermansia muciniphila supplementation in healthy dogs following antimicrobial administration.
American journal of veterinary research.
79(8):884-892
[DOI] 10.2460/ajvr.79.8.884.
[PMID] 30058857.
2018
Pharmacodynamics and pharmacokinetics of insulin aspart assessed by use of the isoglycemic clamp method in healthy cats.
Domestic animal endocrinology.
62:60-66
[DOI] 10.1016/j.domaniend.2017.09.002.
[PMID] 29101821.
2018
Pharmacodynamics and pharmacokinetics of insulin detemir and insulin glargine 300 U/mL in healthy dogs.
Domestic animal endocrinology.
64:17-30
[DOI] 10.1016/j.domaniend.2018.03.007.
[PMID] 29709796.
2018
The effect of diet, adiposity, and weight loss on the secretion of incretin hormones in cats.
Domestic animal endocrinology.
62:67-75
[DOI] 10.1016/j.domaniend.2017.10.004.
[PMID] 29128557.
2017
Aldehyde dehydrogenase 1 a1 regulates energy metabolism in adipocytes from different species.
Xenotransplantation.
24(5)
[DOI] 10.1111/xen.12318.
[PMID] 28718514.
2017
Dietary management of presumptive protein-losing enteropathy in Yorkshire terriers.
The Journal of small animal practice.
58(2):103-108
[DOI] 10.1111/jsap.12625.
[PMID] 28160309.
2017
Nano-Encapsulation of Bilirubin in Pluronic F127-Chitosan Improves Uptake in β Cells and Increases Islet Viability and Function after Hypoxic Stress.
Cell transplantation.
26(10):1703-1715
[DOI] 10.1177/0963689717735112.
[PMID] 29251115.
2017
Sensitivity of fecal occult blood testing in the cat.
Journal of feline medicine and surgery.
19(6):603-608
[DOI] 10.1177/1098612X16643752.
[PMID] 27084754.
2017
The Diabetic Dog as a Translational Model for Human Islet Transplantation.
The Yale journal of biology and medicine.
90(3):509-515
[PMID] 28955189.
2017
Therapy of Canine Hyperlipidemia with Bezafibrate.
Journal of veterinary internal medicine.
31(3):717-722
[DOI] 10.1111/jvim.14701.
[PMID] 28382723.
2017
Use of a combination of routine hematologic and biochemical test results in a logistic regression model as a diagnostic aid for the diagnosis of hypoadrenocorticism in dogs.
American journal of veterinary research.
78(10):1171-1181
[DOI] 10.2460/ajvr.78.10.1171.
[PMID] 28945131.
2017
Use of probiotics in small animal veterinary medicine.
Journal of the American Veterinary Medical Association.
250(5):519-528
[DOI] 10.2460/javma.250.5.519.
[PMID] 28207322.
2016
Leptin Production by Encapsulated Adipocytes Increases Brown Fat, Decreases Resistin, and Improves Glucose Intolerance in Obese Mice.
PloS one.
11(4)
[DOI] 10.1371/journal.pone.0153198.
[PMID] 27055280.
2016
New Approaches to Feline Diabetes Mellitus: Glucagon-like peptide-1 analogs.
Journal of feline medicine and surgery.
18(9):733-43
[DOI] 10.1177/1098612X16660441.
[PMID] 27562982.
2016
TREATMENT OF DIABETES MELLITUS IN A GOLDEN LION TAMARIN (LEONTOPITHECUS ROSALIA) WITH THE GLUCAGON-LIKE PEPTIDE-1 MIMETIC EXENATIDE.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
47(3):903-906
[PMID] 27691959.
2016
What’s in a Name? Classification of Diabetes Mellitus in Veterinary Medicine and Why It Matters.
Journal of veterinary internal medicine.
30(4):927-40
[DOI] 10.1111/jvim.14357.
[PMID] 27461721.
2015
Adrenal insufficiency secondary to lymphocytic panhypophysitis in a cat.
Australian veterinary journal.
93(9):327-31
[DOI] 10.1111/avj.12354.
[PMID] 26313211.
2015
Duration of fasting but not diurnal variation affects the response to glucagon in healthy cats.
Domestic animal endocrinology.
53:103-7
[DOI] 10.1016/j.domaniend.2015.05.004.
[PMID] 26201763.
2015
Feline hyperparathyroidism: pathophysiology, diagnosis and treatment of primary and secondary disease.
Journal of feline medicine and surgery.
17(5):427-39
[DOI] 10.1177/1098612X15581134.
[PMID] 25896242.
2015
Pharmacokinetics and pharmacodynamics of the glucagon-like peptide-1 analog liraglutide in healthy cats.
Domestic animal endocrinology.
51:114-21
[DOI] 10.1016/j.domaniend.2014.12.001.
[PMID] 25625650.
2015
Pharmacology of the glucagon-like peptide-1 analog exenatide extended-release in healthy cats.
Domestic animal endocrinology.
51:78-85
[DOI] 10.1016/j.domaniend.2014.12.003.
[PMID] 25594949.
2015
Synchronous Diaphragmatic Flutter Secondary to Primary Hypoparathyroidism in a Dog.
Journal of the American Animal Hospital Association.
51(6):392-5
[DOI] 10.5326/JAAHA-MS-6235.
[PMID] 26535458.
2015
What is your diagnosis? Biliary tract obstruction.
Journal of the American Veterinary Medical Association.
246(3):295-7
[DOI] 10.2460/javma.246.3.295.
[PMID] 25587727.
2014
Evaluation of a high-yield technique for pancreatic islet isolation from deceased canine donors.
Domestic animal endocrinology.
47:119-26
[DOI] 10.1016/j.domaniend.2013.01.006.
[PMID] 23428563.
2014
Pancreatic islet transplantation: from dogs to humans and back again.
Veterinary surgery : VS.
43(6):631-41
[DOI] 10.1111/j.1532-950X.2014.12224.x.
[PMID] 24909456.
2013
Distribution of K and L cells in the feline intestinal tract.
Domestic animal endocrinology.
45(1):49-54
[DOI] 10.1016/j.domaniend.2013.04.004.
[PMID] 23751572.
2011
Common laboratory artifacts caused by inappropriate sample collection and transport: how to get the most out of a sample.
Topics in companion animal medicine.
26(2):109-18
[DOI] 10.1053/j.tcam.2011.02.003.
[PMID] 21596350.
2011
DIC and granulomatous vasculitis in a dog with disseminated histoplasmosis.
Journal of the American Animal Hospital Association.
47(3):e26-30
[DOI] 10.5326/JAAHA-MS-5510.
[PMID] 21531969.
2011
Interpretation of laboratory tests for canine Cushing’s syndrome.
Topics in companion animal medicine.
26(2):98-108
[DOI] 10.1053/j.tcam.2011.03.001.
[PMID] 21596349.
2011
Introduction: Clinical pathology and hematology.
Topics in companion animal medicine.
26(2):43-4
[DOI] 10.1053/j.tcam.2011.04.001.
[PMID] 21596343.
2011
The GLP-1 mimetic exenatide potentiates insulin secretion in healthy cats.
Domestic animal endocrinology.
41(1):42-9
[DOI] 10.1016/j.domaniend.2011.03.001.
[PMID] 21645806.
2011
The incretin effect in cats: comparison between oral glucose, lipids, and amino acids.
Domestic animal endocrinology.
40(4):205-12
[DOI] 10.1016/j.domaniend.2011.01.002.
[PMID] 21397435.
2010
Pharmacodynamics of insulin detemir and insulin glargine assessed by an isoglycemic clamp method in healthy cats.
Journal of veterinary internal medicine.
24(4):870-4
[DOI] 10.1111/j.1939-1676.2010.0544.x.
[PMID] 20561185.
2010
Phenobarbital-responsive sialadenosis associated with an esophageal foreign body in a dog.
Journal of the American Animal Hospital Association.
46(2):115-20
[PMID] 20194367.
2010
Synthetic insulin analogs and their use in dogs and cats.
The Veterinary clinics of North America. Small animal practice.
40(2):297-307
[DOI] 10.1016/j.cvsm.2009.11.001.
[PMID] 20219490.
2010
The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats.
Veterinary clinical pathology.
39(3):322-8
[DOI] 10.1111/j.1939-165X.2010.00227.x.
[PMID] 20412547.
2006
Clinical aspects of natural infection with Blastomyces dermatitidis in cats: 8 cases (1991-2005).
Journal of the American Veterinary Medical Association.
229(1):96-9
[PMID] 16817721.
Grants
Mar 2024
ACTIVE
IVX-08 for treatment of obesity and diabetes in cats
Role: Principal Investigator
Funding: INVETX
Feb 2024
– Aug 2024
Ceva Animal Health, LLC, Insulin Receptor Agonist in cats
Role: Principal Investigator
Funding: CEVA SANTE ANIMALE S.A.
Jun 2023
ACTIVE
Edge Animal Health Canine Inducible-Insulin project
Role: Principal Investigator
Funding: EDGE ANIMAL HEALTH
May 2023
ACTIVE
A pilot field study to evaluate the efficacy and safety of DP1380, a novel, long acting insulin, administered via weekly injections using a prescribed dosing scheme in dogs with diabetes mellitus
Role: Principal Investigator
Funding: DECHRA PHARMACEUTICALS
Jan 2023
– Dec 2023
BiomEdit-designed strains of Lactobacillus
Role: Principal Investigator
Funding: BIOMEDIT
Dec 2021
ACTIVE
MONITORING OF TYPE 2 DIABETES MELLITUS IN CATS WITH FELAQUA: COMPARISON TO CGM
Role: Principal Investigator
Funding: MERCK ANIMAL HEALTH
Feb 2021
– Feb 2023
Selective osmotic shock for Islet isolation in the feline pancreas
Role: Other
Funding: AM COLL OF VET INTERNAL MED
via NESTLE PURINA PETCARE COMPANY
Feb 2021
– Jun 2024
Potential reduction of systemic and pancreatic inflammation using fenofibrate in diabetic dogs
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
May 2020
– Apr 2023
Efficacy and Safety Pilot Study of OKV-119 in Obese Client-Owned Cats
Role: Principal Investigator
Funding: OKAVA PHARMACEUTICALS
Education
Doctor of Philosophy
2010
·
College of Veterinary Medicine, University of Illinois at Urbana-Champaign
Diplomate, American College of Veterinary Internal Medicine
2008
·
College of Veterinary Medicine, University of Illinois at Urbana-Champaign
Residency, Small Animal Internal Medicine
2008
·
University of Illinois at Urbana-Champaign
Internship
2005
·
Animal Medical Center, New York City, New York
Doctor of Veterinary Medicine
1998
·
Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Israel
Contact Details
Phones:
- Business:
- (352) 392-2235
Emails:
- Business:
- cgilor@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100126
GAINESVILLE FL 32610 - Business Street:
-
SAH BLDG. 75, SAH 368
PO BOX 100116
PO BOX 100116
GAINESVILLE FL 32610