Daniel R Brown

Daniel R Brown,

Associate Professor

Department: Department of Infectious Diseases & Immunology
Business Phone: (352) 294-4004
Business Email: drbrown@ufl.edu

Accomplishments

IOM Founders Award for outstanding advances in mycoplasmology
2021 · International Organization for Mycoplasmology
Bergey Medal for outstanding contributions to the field of systematics of bacteria and archaea
2020 · Bergey's Manual Trust
Top Peer Reviewer in Microbiology
2019 · Web of Science
UF CVM Teacher of the Year nominee
2019 · UF CVM Class of 2021
Master Mentor
2017 · University of Florida
Outstanding Reviewer Award
2015 · Elsevier Veterinary Immunology and Immunopathology
Who’s Who in Veterinary Medicine Higher Education
2008-2009 · Who’s Who in Veterinary Medicine Higher Education
National Honor Society of Veterinary Medicine
2007 · Phi Zeta National Honor Society of Veterinary Medicine
Derrick Edward Award for Outstanding Research in Mycoplasmology
2004 · International Organization for Mycoplasmology
C.E. Cornelius Young Investigator Award
1994 · University of Florida College of Veterinary Medicine

Research Profile

Cellular microbiology focuses on the host cell responses elicited by interactions with microorganisms. Recent and ongoing research in my laboratory includes culture- and non-culture-based discovery of new bacterial pathogens and commensals from clinical specimens; experimental infection studies and epidemiology; bacterial genome sequencing and annotation; molecular analysis of bacterial virulence mechanisms; comparative immunology; CD44, CD95, and TLR signaling in pro-apoptotic and inflammatory responses to bacterial infection; and genome-based predictive modeling of pathogen evolution.

Publications

2019
Complete Sequence and Annotation of the Mycoplasma phocicerebrale Strain 1049T Genome.
Microbiology resource announcements. 8(25) [DOI] 10.1128/MRA.00514-19. [PMID] 31221652.
2019
Complete Sequence and Annotation of the Mycoplasma phocirhinis Strain 852T Genome.
Microbiology resource announcements. 8(13) [DOI] 10.1128/MRA.00131-19. [PMID] 30923243.
2019
Sialidase and N-acetylneuraminate catabolism in nutrition of Mycoplasma alligatoris.
Microbiology (Reading, England). 165(6):662-667 [DOI] 10.1099/mic.0.000739. [PMID] 30422107.
2018
Complete Sequence and Annotation of the Mycoplasma phocidae Strain 105T Genome.
Microbiology resource announcements. 7(14) [DOI] 10.1128/MRA.01237-18. [PMID] 30533705.
2018
Notice of impending dissolution of inactive Subcommittees on Taxonomy.
International journal of systematic and evolutionary microbiology. 68(6):2102-2103 [DOI] 10.1099/ijsem.0.002587. [PMID] 29688167.
2017
International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Mollicutes. Minutes of the closed meeting, 3rd July 2016, Brisbane, Australia.
International journal of systematic and evolutionary microbiology. 67(7):2482-2484 [DOI] 10.1099/ijsem.0.001818. [PMID] 28693682.
2016
Cellular Microbiology of Mycoplasma canis.
Infection and immunity. 84(6):1785-1795 [DOI] 10.1128/IAI.01440-15. [PMID] 27045036.
2016
Identification of a Novel Mycoplasma Species in a Patient With Septic Arthritis of the Hip and Seal Finger.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 62(4):491-3 [DOI] 10.1093/cid/civ875. [PMID] 26449564.
2015
Complete Genome Sequence of Mycoplasma synoviae Strain WVU 1853T.
Genome announcements. 3(3) [DOI] 10.1128/genomeA.00563-15. [PMID] 26021934.
2014
A sialoreceptor binding motif in the Mycoplasma synoviae adhesin VlhA.
PloS one. 9(10) [DOI] 10.1371/journal.pone.0110360. [PMID] 25338071.
2014
Mycoplasmosis and upper respiratory tract disease of tortoises: a review and update.
Veterinary journal (London, England : 1997). 201(3):257-64 [DOI] 10.1016/j.tvjl.2014.05.039. [PMID] 24951264.
2013
Sialidase activity in aerobic vaginitis is equal to levels during bacterial vaginosis.
European journal of obstetrics, gynecology, and reproductive biology. 167(2):205-9 [DOI] 10.1016/j.ejogrb.2012.12.003. [PMID] 23375395.
2012
Effects of sialidase knockout and complementation on virulence of Mycoplasma gallisepticum.
Veterinary microbiology. 157(1-2):91-5 [DOI] 10.1016/j.vetmic.2011.12.004. [PMID] 22197303.
2011
Diversity of expressed vlhA adhesin sequences and intermediate hemagglutination phenotypes in Mycoplasma synoviae.
Journal of bacteriology. 193(9):2116-21 [DOI] 10.1128/JB.00022-11. [PMID] 21378196.
2011
Retrospective survey for sialidase activity in Mycoplasma pneumoniae isolates from cases of community-acquired pneumonia.
BMC research notes. 4 [DOI] 10.1186/1756-0500-4-195. [PMID] 21676241.
2009
Diversifying and stabilizing selection of sialidase and N-acetylneuraminate catabolism in Mycoplasma synoviae.
Journal of bacteriology. 191(11):3588-93 [DOI] 10.1128/JB.00142-09. [PMID] 19329630.
2009
Secreted sialidase activity of canine mycoplasmas.
Veterinary microbiology. 137(3-4):380-3 [DOI] 10.1016/j.vetmic.2009.01.009. [PMID] 19201110.
2008
Effect of organic or inorganic trace mineral supplementation on follicular response, ovulation, and embryo production in superovulated Angus heifers.
Animal reproduction science. 106(3-4):221-31 [PMID] 17513073.
View on: PubMed
2008
Evanescent-wave biosensor for field serodiagnosis of tortoise mycoplasmosis.
Veterinary immunology and immunopathology. 124(3-4):322-31 [DOI] 10.1016/j.vetimm.2008.04.009. [PMID] 18499267.
2008
Genetic variation in sialidase and linkage to N-acetylneuraminate catabolism in Mycoplasma synoviae.
Microbial pathogenesis. 45(1):38-44 [DOI] 10.1016/j.micpath.2008.02.002. [PMID] 18490131.
2007
Improved enzyme-linked immunosorbent assay to reveal Mycoplasma agassizii exposure: a valuable tool in the management of environmentally sensitive tortoise populations.
Clinical and vaccine immunology : CVI. 14(9):1190-5 [PMID] 17626160.
View on: PubMed
2007
Mycoplasma insons sp. nov., a twisted mycoplasma from green iguanas (Iguana iguana).
FEMS microbiology letters. 274(2):298-303 [PMID] 17697083.
View on: PubMed
2007
Mycoplasmosis in green iguanas (Iguana iguana).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 38(2):348-51 [PMID] 17679524.
View on: PubMed
2007
Revised minimal standards for description of new species of the class Mollicutes (division Tenericutes).
International journal of systematic and evolutionary microbiology. 57(Pt 11):2703-2719 [DOI] 10.1099/ijs.0.64722-0. [PMID] 17978244.
2007
Role of sialidase in Mycoplasma alligatoris-induced pulmonary fibroblast apoptosis.
Veterinary microbiology. 121(1-2):73-82 [PMID] 17276629.
View on: PubMed
2007
Sialidase activity in Mycoplasma synoviae.
Avian diseases. 51(4):829-33 [PMID] 18251389.
View on: PubMed
2006
In vitro antibiotic susceptibility of Mycoplasma iguanae proposed sp. nov. isolated from vertebral lesions of green iguanas (Iguana iguana).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 37(2):206-8 [PMID] 17312804.
View on: PubMed
2006
Lesions associated with a novel Mycoplasma sp. in California sea lions (Zalophus californianus) undergoing rehabilitation.
Journal of wildlife diseases. 42(1):40-5 [PMID] 16699147.
View on: PubMed
2006
Mycoplasma iguanae sp. nov., from a green iguana (Iguana iguana) with vertebral disease.
International Journal of Systematic and Evolutionary Microbiology. 56(Pt 4):761-764 [DOI] 10.1099/ijs.0.63852-0. [PMID] 16585690.
2005
Seroprevalence of Mycoplasma alligatoris among free-ranging alligators (Alligator mississippiensis) in Florida–2003.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 36(2):340-1 [PMID] 17323582.
View on: PubMed
2004
Mycoplasma testudineum sp. nov., from a desert tortoise (Gopherus agassizii) with upper respiratory tract disease.
International journal of systematic and evolutionary microbiology. 54(Pt 5):1527-1529 [DOI] 10.1099/ijs.0.63072-0. [PMID] 15388705.
2004
Spreading factors of Mycoplasma alligatoris, a flesh-eating mycoplasma.
Journal of bacteriology. 186(12):3922-7 [DOI] 10.1128/JB.186.12.3922-3927.2004. [PMID] 15175306.
2002
In vitro drug susceptibility pattern of Mycoplasma alligatoris isolated from symptomatic American alligators (Alligator mississippiensis).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 33(2):108-11 [PMID] 12398297.
View on: PubMed
2002
Mycoplasmosis and immunity of fish and reptiles.
Frontiers in bioscience : a journal and virtual library. 7:d1338-46 [PMID] 11991833.
View on: PubMed
2001
Mycoplasma agassizii sp. nov., isolated from the upper respiratory tract of the desert tortoise (Gopherus agassizii) and the gopher tortoise (Gopherus polyphemus).
International journal of systematic and evolutionary microbiology. 51(Pt 2):413-418 [DOI] 10.1099/00207713-51-2-413. [PMID] 11321087.
2001
Mycoplasma alligatoris sp. nov., from American alligators.
International journal of systematic and evolutionary microbiology. 51(Pt 2):419-424 [DOI] 10.1099/00207713-51-2-419. [PMID] 11321088.
2001
Mycoplasma microti sp. nov., isolated from the respiratory tract of prairie voles (Microtus ochrogaster).
International journal of systematic and evolutionary microbiology. 51(Pt 2):409-412 [DOI] 10.1099/00207713-51-2-409. [PMID] 11321086.
2001
Pathology of experimental mycoplasmosis in American alligators.
Journal of wildlife diseases. 37(4):671-9 [PMID] 11763730.
View on: PubMed
1999
Upper respiratory tract disease in the gopher tortoise is caused by Mycoplasma agassizii.
Journal of clinical microbiology. 37(7):2262-9 [PMID] 10364595.
View on: PubMed

Grants

Jan 2020 – Jun 2021
LM40 PCR Sensitivity Study
Role: Principal Investigator
Funding: ALASKA DEPARTMENT OF FISH AND GAME via US DEPT OF INTERIOR FISH AND WILDLIFE SE
Jun 2018 – May 2019
22nd Congress of the International Organization for Mycoplasmology
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Oct 2009 ACTIVE
Diagnostic testing for multiple sponsors.
Role: Principal Investigator
Funding: MULTIPLE SPONSORS

Education

PhD – Genetics
1987 · University of Arizona
MS – Quantitative Genetics
1980 · Louisiana State University

Teaching Profile

Courses Taught
2008,2014-2016,2016-2019
VME6905 Problems in Veterinary Medical Sciences
2006,2009-2019
VEM5141 Vet Microbiology
2009
VME4906 Problems in Veterinary Science
2008-2009
VEM5503 Vet Epidemiology

Contact Details

Phones:
Business:
(352) 294-4004
Emails:
Business:
drbrown@ufl.edu