Donald C Bolser

Donald C Bolser

Professor

Department: Department of Physiological Sciences
Business Phone: (352) 294-4026
Business Email: bolser@ufl.edu

Accomplishments

UF Research Foundation Professorship
2017-2020 · University of Florida
UF Term Professorship,
2017 · University of Florida
UF Research Foundation Professorship
2016 · University of Florida
Member
2016 · Animal Care and Experimentation Committee, American Physiological Society
External referee
2016 · Research Foundation
UF Termed Professor – Research Foundation Professor
2013-2017 · University of Florida
Member
2013 · NIH study section for P50 Clinical Research Center grant
Member, Panel on Evidence-based Clinical Practice Guidelines for Diagnosis and Management of Cough
2011 · American College of Chest Physicians
Co-Chair, organizer and invited speaker, Airway Protective Behaviors: Cough and Swallow
2010 · Experimental Biology Meeting Symposium
Animal Health Award for Research Excellence
2008 · Pfizer
Editorial Board
2005-2019 · Journal of Applied Physiology

Research Profile

Cough is the most common reason why sick patients visit physicians in the US. This defensive reflex is the most common manifestation of tobacco- and non-tobacco-related pulmonary diseases. Furthermore, cough suppressant (also called antitussive) drugs are among the most commonly prescribed in the world. Significant gaps exist in our understanding of how cough is produced and how this defensive reflex is inhibited by antitussive drugs. The long-range goal of research in our laboratory is to delineate the how the nervous system produces and regulates cough. We use antitussive drugs as tools to determine how the cough system is controlled. As such, our work also will expand our knowledge of the mechanisms by which these drugs inhibit cough. Our current approach incorporates the use of multiple extracellular electrode array technology to investigate the behavior of spontaneously active and recruited neurons in the brainstem during cough. Determination of the identity and functional relationships between these neurons will allow modeling of the configuration of the brainstem cough network. Perturbation of the behavior of these neurons with antitussive drugs will allow us to identify the mechanism by which cough suppressants act to inhibit this behavior.

Publications

2015 Pulmonary Pharmacology & Therapeutics
2014 Frontiers in physiology
2012 Journal of Applied Physiology
2011 Bratislava Medical Journal-Bratislavske Lekarske Listy
2011 Pulmonary Pharmacology & Therapeutics
2010 Journal of Applied Physiology
2010 Otolaryngologic clinics of North America
2009 Pulmonary Pharmacology & Therapeutics
2009 Respiratory Physiology & Neurobiology
2009 Respiratory Physiology & Neurobiology
2009 Pulmonary Pharmacology & Therapeutics
2009 Handbook of Experimental Pharmacology
2007 Current Opinion in Allergy and Clinical Immunology
2006 Respiratory Physiology & Neurobiology
2004 Pulmonary Pharmacology & Therapeutics
2002 Progress in Brain Research
2002 Pulmonary Pharmacology & Therapeutics
2001 European Journal of Pharmacology

Grants

Dec 2016 ACTIVE
Modeling the role of the NTS in the neurogenesis of airway defensive behaviors
NATL INST OF HLTH NHLBI · Principal Investigator
Sep 2016 ACTIVE
Functional mapping of peripheral and central circuits for airway protection and breathing
NATL INST OF HLTH OD · Principal Investigator
Dec 2015 – Dec 2016
Modeling the role of the NTS in the neurogenesis
UF FOU · Principal Investigator
Jun 2012 – May 2016
Brainstem respiratory neuron interactions
UNIV OF SOUTH FLORIDA · Principal Investigator

Patents

Issued May 2015
Protecting Airways (combined with 14739)
#9,042,992
Issued June 2016
Controlling Coughing and Swallowing (combined with 14242)
#9,375,568

Education

PhD – Physiology
1985 · University of South Florida

Contact Details

Phones:
Business:
(352) 294-4026
Emails:
Business:
bolser@ufl.edu

University of Florida

IFAS

As part of both the Institute of Food and Agricultural Sciences and UF Health, Veterinary Medicine is dedicated to advancing animal, human and environmental health through teaching, research, extension and patient care.

IFAS

UNIVERSITY OF FLORIDA

Animal Hospitals

Need animal care? Visit the UF Small Animal and Large Animal Hospitals. From dogs, cats, birds and exotics to horses, cattle, llamas, pigs and many other large farm or food animals, our experienced veterinarian staff is ready to assist.

Animal Airwaves

Syndicated Podcast

Animal Airwaves

Animal Airwaves is a daily radio series that features one-minute segments relating to animal health, ranging from insights into animal behavior to veterinary patient care breakthroughs and trends.

Animal Airwaves