Leah R. Reznikov

Assistant ProfessorDr. Leah Reznikov

Department of Physiological Sciences
Box 100144
Gainesville, FL 32610-0144
leahreznikov@ufl.edu
Office: 352-294-4059
Fax: 352-392-5145
Reznikov Lab

Education

  • 08/2008 – 06/2016: Postdoctoral Scholar, Lung Biology and Cystic Fibrosis Center, University of Iowa, Iowa City, IA
  • 08/2004 – 08/2008: Ph.D, Biomedical Sciences; focus in Neuroscience. University of South Carolina School of Medicine, Columbia, SC
  • 02/2000 – 06/2000: Regents Semester Study Abroad Program. University of Newcastle, Newcastle, New South Wales, Australia
  • 08/1998 – 08/2002: B.S., Biology. Iowa State University, Ames, IA

Honors and Awards

  • 2018: Pew Scholarship Program Candidate UF Representative, 2018
  • 2017: Matching Funds Award Dovetail Genomics
  • 2017: New York Academy of Sciences STEM Mentor
  • 2017: University of South Carolina School of Medicine Distinguished Doctorate Alumni Award
  • 2014: K99/R00 Pathway to Independence Grant Recipient
  • 2014: University of Iowa 15th Annual Interdisciplinary Research Poster Session Best Poster Award
  • 2014: University of Iowa Carver College of Medicine Health Sciences Research Week Cover Art Winner
  • 2013: University of Iowa 14th Annual Interdisciplinary Research Poster Session Women in Science and Engineering Award
  • 2013: University of Iowa Carver College of Medicine Health Sciences Research Week Outstanding Poster Award in Postdoctoral Fellow and Staff Category
  • 2012: University of Iowa Carver College of Medicine Health Sciences Research Week Outstanding Poster Award in Postdoctoral Fellow and Staff Category
  • 2010: NIH T32 Institutional NRSA Postdoctoral Fellowship Recipient, Cardiovascular Center, Internal Medicine,  University of Iowa
  • 2007: International Society of Psychoneuroendocrinology Young Investigator Travel Award
  • 2007: Amygdala in Health & Disease Gordon Conference Chair’s Fund Recipient
  • 2006: Society for Neuroscience Graduate Student Travel Award
  • 2004: Research Assistantship from the Graduate School of University of South Carolina School of Medicine
  • 1998-2002: Iowa State University Academic Recognition Scholarship

Current Grant Support

Neural Pathogenesis of Airway Smooth Muscle Defects in Airway Disease
05/01/14-07/31/19  PI NIH R00HL119560

Functional Mapping of Peripheral and Central Circuits for Airway Protective Behaviors
09/30/16-07/31/19 Co-I (Dr. Don Bolser, PI)  NIH 10T2TR001983

Research Interests

The research interests of my lab are centered on the interface of the nervous system and the airway. Using multidisciplinary approaches, we aim to answer three big picture questions:  1) Is dysfunction of the nervous system sufficient to induce airway disease? 2) What are the neural substrates that detect airway insults? 3) Can targeting the nervous system prevent airway disease?

To answer these questions, we use models of asthma and cystic fibrosis, with a special emphasis on early stage life.  We perform in vitro and in vivo studies in parallel, and utilize numerous techniques ranging from basic molecular biology to microscopy to ion transport studies to whole animal physiology.  We are keenly interested in the communication of the sensory nerves with the airway, and the processes governing transmission of that information to target tissues (i.e. epithelia, smooth muscle, submucosal glands, brainstem, etc).  The goal of all our efforts is to improve human health and discover new mechanisms of airway disease.

Recent Publications

  1. Reznikov LR, Liao YSJ, Gu T, Davis K, Kuan SP, Atanasova KR, Dadural JS, Collins EN, Guevara MV, Vogt KM (2018) Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid. AJP-Lung. In press.
  2. Atanasova KR, Reznikov LR (2018) Neuropeptides in asthma, chronic obstructive pulmonary disease and cystic fibrosis. Respiratory Research.  Aug 6; 19(1):149.
  3. Reznikov LR, Meyerholz DK, Abou Alaiwa MHA, Kuan SP, Liao YSK, Bormann N, Bair, T, Price M, Stoltz, DA, Welsh MJ. Vagal Ganglia Transcriptome Identifies Candidate Therapeutics for Airway Hyperreactivity (2018) AJP-Lung. Aug 1;315(2):L133-L148.
  4. Reznikov LR, Meyerholz DK, Kuan SP, Guevara M, Atanasova KR, Abou Alaiwa, MHA. Solitary Cholinergic Stimulation Induces Airway Hyperreactivity and Transcription of Distinct Pro-inflammatory Pathways. (2018) Apr; 196(2):219-229.

Additional publications

Additional publications here

 

Last updated 3 Dec 2018