College of Veterinary Medicine

Education:

DVM, University of Florida, 1988
Residency in Small Animal Medicine, University of Florida, 1992
Residency in Laboratory Animal Medicine, University of Florida, 1999
Ph.D, University of Florida, 1999

Honors and Awards:

1984-88 University of Florida, Minority Award for Academic Excellence
1987 Membership to Phi Zeta Veterinary Honor Society
1988 Phi Zeta Award for Academic Excellence
1993-99 University of Florida, Minority Award for Academic Excellence
1999 University of Florida, Excellence in Doctoral Studies

Research Interests:

My overall research interest is to elucidate host-pathogen relationships that determine whether an individual develops disease or overcomes infection without an adverse outcome. My current research is focused on urogenital tract diseases, specifically, urinary tract infection with and without stone formation, and adverse pregnancy outcome secondary to intrauterine infection. I work mainly with opportunistic bacterial pathogens from the class mollicutes, but I also work with Porphomonas gingivalis as part of a collaborative project with the College of Dentistry. As part of my approach I develop animal models of human disease with the intention to elucidate the host specific factors that confer disease susceptibility or resistance to infection. Through the use of microbiology, genomics, proteomics and computational biology, my goal is to identify biomarkers of disease susceptibility as well as delineate the host specific gene regulatory networks that contribute to adverse outcome secondary to infection.

Selected Publications:

For Publications Extracted From Medline Click HERE

Reyes L., Reinhard, M, O’Donell, LJ, Stevens, J. and Mary B. Brown. 2006 Rat Strains Differ in Susceptibility to Ureaplasma Induced UTI and Struvite Stone Formation. Infect. & Immun. 74:6656-64.

Edwards RK, Ferguson RJ, Reyes L, Brown M, Theriaque DW, and Duff P. 2006. Assessing the relationship between preterm delivery and various microorganisms recovered from the lower genital tract. J Matern Fetal Neonatal Med 19:357-63.

Reyes, L., Shelton, M., Hillier, M., and M.B. Brown. 2004. Rat strains differ in susceptibility to maternal and fetal infection with Mycoplasma pulmonis. Am J. Reprod. Immun. 51:1-9.

Brown, M.B., Peltier, M., Hillier, M., Crenshaw, B. and L. Reyes 2001. Genital mycoplasmosis in rats: a model for intrauterine infection. Am. J. Reprod. Immun. 46:232-241.

Reyes, L., D. Steiner, J. Hutchison, B. Crenshaw, and M.B. Brown. 2000. Mycoplasma pulmonis genital disease: effect of rat strain on pregnancy outcome. Comparative Medicine, 50(6):622-627.

Davis, J.K., Crouse, D.T., Robertson, J.A., Davidson, M.K., M.B. Brown, and L.Reyes. 1999. The role of Ureaplasma urealyticum in human reproductive and neonatal diseases. The Infect. Dis. Rev. 1(3):200-207.

Reyes, L., Davidson, M.K., Thomas, L.T., and J.K. Davis. 1999. Effects of Mycoplasma fermentans incognitus strain on the differentiation of THP-1 cells. Infect. Immun. 67(7):3188-3192.