College of Veterinary Medicine

Education:

DVM, Veterinary Medicine, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru, 1966
DipTVM, Tropical Veterinary Medicine, Royal (Dick) School of Veterinary Studies, University of Edinburgh, United Kingdom, 1968
MSc, Animal Virology, Royal (Dick) School of Veterinary Studies, University of Edinburgh, United Kingdom, 1969
PhD, Poultry Science, Avian Virology, Michigan State University, East Lansing, MI, USA, 1977

Research Interests:

Over the last decade, research in my laboratories has concentrated on the development of molecular assays for the early detection and characterization of viruses of livestock and poultry. We have also been involved in the development of genetically engineered recombinant DNA viruses and DNA molecules with potential vaccine use in poultry and livestock. More recently, we have concentrated on the development of diagnostic assays to identify novel viruses of marine mammals that may be associated with disease and stranding. Present efforts emphasize obtaining complete gene sequences from these viruses to determine genetic relatedness and diversity in different marine mammal species and on their protein expression to develop serological assays.

Selected Publications:

For Publications Extracted From Medline Click HERE

McClenahan, S.D., Bok, K., Sosnovtsev, S.V., Neill, J.D., Burek, K.A., Beckmen, K.B., Green, K.Y., Romero, C.H. 2009. Expression and self-assembly of virus-like particles from two genotypes of marine vesiviruses and development of an ELISA for the detection of antibodies.  Veterinary Microbiology, (Accepted)

McClenahan S.D., Neill, J.D., Smith, A.W., Romero, C.H. 2009.  A capsid gene-based real-time reverse transcription polymerase chain reaction assay for the detection of marine vesiviruses in the Caliciviridae.  Journal of Virological Methods, 161, 12-18. 

Grant, R.J., Banyard, A.C., Barrett, T., Saliki, J.T., Romero, C.H. 2009.  Real-time RT-PCR assays for the rapid and differential detection of dolphin and porpoise morbilliviruses. Journal of Virological Methods, 156, 117-123.

McClenahan, S.D., Burek, K.A., Beckmen, K.B., Knowles, N.J., Neill, J.D., Romero, C.H. 2008.  Genomic characterization of novel marine vesiviruses from Steller sea lions (Eumetopias jubatus) from Alaska. Virus Research, 138, 26-35. 

Banyard, A.C, Grant, R.J., Romero, C.H., Barrett, T. 2008.  Sequence of the nucleocapsid gene and genome and antigenome promoters for an isolate of porpoise morbillivirus. Virus Research, 132 (1-2): 213-219. 

Smolarek-Benson, K.A., Manire, C.A., Ewing, R.Y., Saliki, J.T., Townsend, F.I., Ehlers, B., Romero, C.H. 2006. Identification of novel alpha- and gamma herpesviruses from cutaneous and mucosal lesions of dolphins and whales. Journal of Virological Methods, 136: 261-266.

Manire, C.A., Smolarek, K.A., Romero, C.H., Kinsel, M.J., Clauss, T.M., Byrd, L. 2006. Proliferative dermatitis associated with a novel alphaherpesvirus in an Atlantic bottlenose dolphin, Tursiops truncatus. Journal of Zoo and Wildlife Medicine, 37: 174-181.

Bracht, A.J., Brudek, R.L., Ewing, R.Y., Manire, C.A., Burek, K.A., Rosa, C., Beckmen, K.B., Maruniak, J.E., Romero, C.H. 2006. Genetic identification of novel poxviruses of cetaceans and pinnipeds. Archives of Virology, 151: 423-438.

Saliki, J. T., Cooper, E.J., Rotstein, D.S., Caseltine, S.L., Pabst, D.A., McLellan, W.A., Govet, P., Harms, C., Smolarek, K.A., Romero, C.H. 2006. A novel gammaherpesvirus associated with genital lesions in a Blainville’s beaked whale (Mesoplodon densirostris). Journal of Wildlife Diseases, 42 (1): 142-148.

Burek, K.A., Beckmen, K., Gelatt, T., Fraser, W., Bracht, A.J., Smolarek, K.A., Romero, C.H. 2005. Poxvirus infection of Steller sea lions (Eumetopias jubatus) in Alaska. Journal of Wildlife Diseases, 41(4): 745-752.

Woodruff, R.A., Bonde, R.K., Bonilla, J.A., Romero, C.H. 2005. Molecular identification of a papilloma virus from cutaneous lesions of captive and free-ranging Florida manatees. Journal of Wildlife Diseases, 41(2): 437-441.

Hulse, D.J., Romero, C. H. 2004. Partial protection against infectious bursal disease virus through DNA-mediated vaccination with the VP2 capsid protein and chicken IL-2 genes. Vaccine, 22: 1249-1259.

Romero, C.H., Meade, P., Santagata, J., Gillis, K., Lollis, G., Hahn, E.C., Gibbs, E.P.J. 1997. Genital infection and transmission of pseudorabies virus in feral swine in Florida, USA. Veterinary Microbiology, 55: 131-139.

Wade-Evans, A.M., Romero, C.H., Mellor, P., Takamatsu, H., Anderson, J., Thevasagayam, J., Fleming, M. J., Mertens, P.P.C., Black, D.N. 1996. Expresssion of the major core structural protein (VP7) of bluetongue virus, by a recombinant capripox virus, provides partial protection of sheep against a virulent heterotypic bluetongue virus challenge. Virology, 220: 227-231.

Romero, C.H., Barrett, T., Kitching, R.P., Bostock, C., Black, D.N. 1995. Protection of goats against peste des petits ruminants with recombinant capripoxviruses expressing the fusion and haemagglutinin protein genes of rinderpest virus. Vaccine, 13: 36-40.