College of Veterinary Medicine

Education:

BS, Biology, Washington State University, Pullman, 1977
MS, Zoology, Washington State University, Pullman, 1981
PhD, Anatomy, University of Kentucky, Lexington, 1984

Honors and Awards:

Teacher of the Year, College of Veterinary Medicine, 1990
Teacher of the Year, Classes of 1992, 1995, 2001, 2002, 2009
SCAVMA Basic Science Teacher of the Year, 1993, 1997, 2007
C.E. Cornelius Young Investigator Award, College of Veterinary Medicine, University of Florida, 1994

Research Interests:

The primary focus of my laboratory is the characterization of excitatory amino acid (e.g., glutamate) systems in the brains of aged rodent, nonhuman primate and human. In particular, our objective is to understand the relationship between excitatory amino acid systems and neuronal death during aging or neuropathology. For these studies, I use quantitative receptor autoradiography and in situ hybridization to study the anatomy, pharmacology and molecular biology of excitatory amino acid receptors and transporters in the aged brain. In addition, I examine the effects of brain lesions and resultant neural plasticity mechanisms on these systems. Finally, I am interested in the role that astrocytes play in regulating the transport of potential excitotoxins and how astrocytes function during aging and disease.

Selected Publications:

For Publications Extracted From Medline Click HERE

Weiss, M.D., Derazi, S., Rossignol, C., Varoqui, H., Erickson, J.D., Kilberg, M.S. and Anderson, K.J. Ontogeny of the neutral amino acid transporter SAT 1/ATA 1 in rat brain. Devol. Brain Res. 143:151-159. 2003.

Anderson, K.J., Fuggacia, I., and Scheff S.W. Fluoro-Jade B labels reactive and quiescent astrocytes in the rodent spinal cord. J. Neurotrauma 20:1223-1231. 2003.

Anderson, K.J., Miller, K.M., Fugaccia, I., and Scheff, S.W. Regional distribution of Fluro-Jade B staining in the hippocampus following traumatic brain injury. Exp. Neurol. 193:125-30. 2005.

Hauser, K.F., Aldrich, J.V., Anderson, K.J., Bakalkin, G., Christie, M.J., Hall, E.D., Knapp, P.E., Scheff, S.W., Singh, I.N., Vissel, B., Woods, A.S., Yakovleva, T., Shippenberg, T.S. Pathobiology of dynorphins in trauma and disease. Frontiers of Bioscience 10:216-235. 2005.

Weiss, M.D., Donnelly, W.H., Rossignol, C., Varoqui, H., Erickson, J.D. and Anderson, K.J. Ontogeny of the neutral amino acid transporter SNAT1 in the developing rat. J. Molec. Histo. 36:301-309. 2005.

Weiss, M.D., Rossignol, C., Sumners, C., and Anderson, K.J. A pH dependent increase in neuronal glutamate efflux in vitro: Possible involvement of ASCT1. Brain Research 1056:105-112. 2005.

Shaw, G., Yang, C., Ellis, R., Anderson, K., Scheff, S., Mickle, J.P., Anderson, D.K., and Howland, D. Neurofilament NF-H as a serum biomarker of neuronal injury. Biochem. Biophys. Research Com. 336;1268-1277. 2005.

Zheng, T, Rossignol, C., Leibovici, A., Anderson, K.J., Steindler, D.A. and Weiss, M.D. Transplantation of multipotent astrocytic stems cells into a rat model of neonatal hypoxic-ischemic encephalopathy. Brain Research 1112:99-105. 2006.

Leibovici, A., Rossignol, C., Erickson, J.D., Varoqui, H., Watanabe, M., Chaudhry, F.A., Anderson, K.J.  and Weiss, M.D. The effects of hypoxia-ischemia on neutral amino acid transporters in the developing brain. Dev. Neurosci.29:268-274. 2007.

Anderson, K., Scheff, S., Miller, K., Roberts, K., Gilmer, L., Cui, Y., and Shaw, G. The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury. J. Neurotrauma 25:1079- 1085. 2008.