College of Veterinary Medicine

Education:

MS, Quantitative Genetics, Louisiana State University, 1980
PhD, Genetics, University of Arizona, 1987

Honors and Awards:

Who's Who in Veterinary Medicine Higher Education, 2008

Phi Zeta National Honor Society of Veterinary Medicine, 2007
International Organization for Mycoplasmology Derrick Edward Award for Outstanding Research in Mycoplasmology, 2004
University of Florida College of Veterinary Medicine C.E. Cornelius Young Investigator Award, 1994

Research Interests:

Cellular microbiology focuses on the host cell responses elicited by interactions with microorganisms. Recent and ongoing research in my laboratory includes culture- and non-culture-based discovery of new bacterial pathogens and commensals from clinical specimens; experimental infection studies and epidemiology; bacterial genome sequencing and annotation; molecular analysis of bacterial virulence mechanisms; comparative immunology; CD44, CD95, and TLR signaling in pro-apoptotic and inflammatory responses to bacterial infection; and genome-based predictive modeling of pathogen evolution.

Selected Publications:

For Publications Extracted From Medline Click HERE

May, M. and D.R. Brown. 2009. Secreted sialidase activity of canine mycoplasmas. Veterinary Microbiology 137:380-383.

May, M. and D.R. Brown. 2009. Diversifying and stabilizing selection of sialidase and N-acetylneuraminate catabolism in Mycoplasma synoviae. Journal of Bacteriology 191:3588-3593.

May, M. and D.R. Brown. 2008. Genetic variation in sialidase and linkage to N-acetylneuraminate catabolism in Mycoplasma synoviae. Microbial Pathogenesis 45:38-44.

Hunt, M.E. and D.R. Brown. 2007. Role of sialidase in Mycoplasma alligatoris-induced pulmonary fibroblast apoptosis. Veterinary Microbiology 121:73-82.

Hunt, M.E. and D.R. Brown. 2005. Mycoplasma alligatoris infection promotes CD95 (FasR) expression and apoptosis of primary cardiac fibroblasts. Clinical and Diagnostic Laboratory Immunology 12:1370-1377.

Brown, D.R., L.A. Zacher and W.G. Farmerie. 2004. Spreading factors of Mycoplasma alligatoris, a flesh-eating mycoplasma. Journal of Bacteriology 186:3922-3927.