College of Veterinary Medicine

Education:

MS, Quantitative Genetics, Louisiana State University, 1980
PhD, Genetics, University of Arizona, 1987

Honors and Awards:

International Organization for Mycoplasmology Derrick Edward Award for Outstanding Research in Mycoplasmology, 2004
University of Florida College of Veterinary Medicine C.E. Cornelius Young Investigator Award, 1994

Research Interests:

Cellular microbiology focuses on the host cell responses elicited by interactions with microorganisms. Recent and ongoing research in my laboratory includes culture- and non-culture-based discovery of new bacterial pathogens and commensals from clinical specimens; experimental infection studies and epidemiology; bacterial genome sequencing and annotation; molecular analysis of bacterial virulence mechanisms; comparative immunology; CD44, CD95, and TLR signaling in pro-apoptotic and inflammatory responses to bacterial infection; and genome-based predictive modeling of pathogen evolution.

Selected Publications:

For Publications Extracted From Medline Click HERE

Hunt, M.E. and D.R. Brown. 2007. Role of sialidase in Mycoplasma alligatoris-induced pulmonary fibroblast apoptosis. Veterinary Microbiology 121:73-82.

Brown, D.R., D.L. Demcovitz, D.R. Plourde', S.M. Potter, M.E. Hunt, R.D. Jones and D.S. Rotstein. 2006. Mycoplasma iguanae sp. nov., from a green iguana (Iguana iguana) with vertebral disease. International Journal of Systematic and Evolutionary Microbiology 56:761-764.

Brown, D.R., L.A. Zacher, L.D. Wendland and M.B. Brown. 2005. Emerging mycoplasmoses in wildlife. In: Mycoplasmas: pathogenesis, molecular biology, and emerging strategies for control. Blanchard, A. and Browning, G., eds. Horizon Scientific Press, Norfolk U.K. pp. 383-414.

Brown, D.R., L.A. Zacher and W.G. Farmerie. 2004. Spreading factors of Mycoplasma alligatoris, a flesh-eating mycoplasma. Journal of Bacteriology 186:3922-3927.

Brown, D.R. 2002. Mycoplasmosis and immunity of fish and reptiles. Frontiers in Bioscience 7:1338-1346.