By Marilee Griffin

Dr. James W. Lloyd

James W. Lloyd, D.V.M., Ph.D., has been named dean of the College of Veterinary Medicine at the University of Florida.

“I am confident that our internationally recognized veterinary college, hospitals and clinics will flourish under Dr. Lloyd’s leadership,” said David S. Guzick, M.D., Ph.D., senior vice president for health affairs at UF and UF&Shands Health System president. “He brings a wealth of expertise to our team. I look forward to working with him in continuing our tradition of excellence as the state’s only college of veterinary medicine.”

Lloyd was chosen after a nationwide search led by co-chairs Teresa A. Dolan, D.D.S., M.P.H., a professor and dean of UF’s College of Dentistry, and John P. Hayes, Ph.D., a professor and dean for research at the Institute of Food and Agricultural Sciences.

“Dr. Lloyd will make an outstanding addition to the leadership team at the University of Florida,” said Hayes. “I am particularly excited by his vision to position the College of Veterinary Medicine at the forefront of efforts to link health sciences, agricultural sciences and veterinary medicine to address some of the most important issues facing our society. He brings a tremendous set of skills to the table, and we are very excited that he will be joining us at the University of Florida.”

Lloyd will officially begin his new job in July, when he will become the college’s sixth permanent dean.

“I’m thrilled with the opportunity to lead the College of Veterinary Medicine at UF,” said Lloyd. “It’s an outstanding institution with a core of exceptional faculty, staff and students. Together with the leadership team, I look forward to working with both internal and external stakeholders to build on the college’s existing strengths in research, teaching and service and to expand the college’s recognition as a respected leader in academic veterinary medicine.”

The unique opportunity to collaborate with the Health Science Center and UF’s Institute of Food and Agricultural Sciences is exciting, Lloyd said. He’s also looking forward to active engagement with alumni and practitioners in the Florida Veterinary Medical Association, and to working closely with Florida’s diverse animal-owning public — including pet owners, horse owners and the livestock industries.

“We look forward to working with Dean Lloyd to grow the size, scope and diversity of these programs and bring ever greater visibility to the College,” said Jack Payne, Ph.D., senior vice president for agriculture and natural resources at IFAS. “IFAS is very proud of its partnership with the College of Veterinary Medicine in our joint research and Extension efforts, such as the Extension efforts in livestock, aquatic animal health, environmental toxicology, the Food Animal Reproduction and Medicine Service and the Food Animal Residue Avoidance Databank.”

Lloyd most recently served as the associate dean for budget, planning and institutional research at Michigan State University’s College of Veterinary Medicine. He maintained joint appointments as a professor in the departments of large animal clinical sciences and agricultural economics at MSU, and was an adjunct professor at MSU’s Eli Broad College of Business.

He earned a doctorate in veterinary medicine from MSU in 1981 and a Ph.D. in agricultural economics from MSU in 1989.

Lloyd has published more than 165 journal articles, technical reports, proceedings and book chapters. He has successfully secured grant funding for veterinary education and animal health projects, as well as for his research interests, which include non-technical behaviors that contribute to veterinarians’ success, markets for veterinary medical services and financial dimensions of veterinary medical education.

In addition, Lloyd has delivered more than 330 presentations and workshops nationally and internationally, including sessions on leadership development, teaching hospital management, curriculum, academic admissions and various scientific topics at 22 of the 28 U.S. colleges/schools of veterinary medicine.

During this time, he also taught extensively in both pre-clinical and clinical courses, with an emphasis on epidemiology, food safety, herd health management, production medicine, veterinary medical career development and veterinary practice management.

Lloyd is an active member of professional veterinary organizations, including the American Veterinary Medical Association, the American Association of Bovine Practitioners and VetPartners. He served on the executive committee of the Michigan Veterinary Medical Association for four years and was its president in 2010.

“Dr. Lloyd’s experience as an agricultural economist, veterinary practitioner, educator and associate dean responsible for budget, planning and institutional research have prepared him well for the leadership position as dean,” said Dolan. “I have no doubt that he will work to develop an outstanding leadership team and advance the College of Veterinary Medicine to one of the top programs in the country.”

Dr. Dan Brown and bioscientist Dina Michaels use a fluorescence microscope to analyze cells of the canine immune system during infection with Mycoplasma canis. (Photo by Maria Farias)

By analyzing the genes of bacteria, University of Florida researchers have moved a step closer to pinpointing how two brain disorders common in small-breed dogs occur.

The researchers found that the bacteria, known as Mycoplasma canis, invade dog’s cells and suppress their immune system responses.

“This could explain how the bacteria are able to enter the brain in certain circumstances,” said lead investigator Daniel Brown, an associate professor of infectious diseases at the UF College of Veterinary Medicine. “If our theory is correct, it is possible that antibiotic therapy aimed at the mycoplasma could be beneficial if the condition is diagnosed early enough.”

The findings, which appear in the August issue of the Journal of Bacteriology, were also presented at the annual meeting of the International Organization for Mycoplasmology in France.

The researchers studied two common brain syndromes called granulomatous meningoencephalomyelitis, or GME, and necrotizing meningoencephalitis, or NME, which occur primarily in small toy-breed dogs such as pugs, Malteses, Yorkshire terriers, Chihuahuas and Pomeranians. The diseases affect the central nervous system, causing brain damage and symptoms such as seizures, decreased alertness and difficulty maintaining balance. There is no cure, but drugs can control the brain inflammation by suppressing the immune system.

No clear data exist on how widespread the disorders are.

“Although reliable information on new and existing cases is pretty scarce or nonexistent, inflammatory central nervous system disease is certainly one of the most common problems we deal with as veterinary neurologists,” said Christopher Mariani, D.V.M., Ph.D., an assistant professor of neurology at North Carolina State University’s College of Veterinary Medicine. Mariana was not involved in the UF study.

The syndromes previously were thought to be caused by a virus or by an attack of the body’s own immune system. But University of Georgia researchers Renee Barber, and Scott Schatzberg, and colleagues, including Brown, reported earlier this year that whereas viruses were absent from the brain tissues of dogs with the diseases, the bacterium Mycoplasma canis was unexpectedly common. Interestingly, the researchers also found traces of the bacteria in some dogs that did not have the disease.

The bacteria would not have been detected by the methods used previously to search for a presumed viral agent.

In the new study, Brown and colleagues examined five strains of Mycoplasma canis isolated from three different parts of the body — the brain, the genital tract and the throat.

They found no difference between the genetic makeup of the bacteria from brain tissue and that of the bacteria from other sites.

What they did find was evidence that the bacteria don’t just sit on the surfaces of cells, but actually penetrate inside cells. That may be what enables entry into the bloodstream and eventually, to the brain, the researchers said.

“This finding is tantalizing, because it may offer an explanation as to why scientists have never been able to specify a viral, autoimmune or other cause of GME and NME,” Brown said.

In addition, different strains of bacteria were not equally efficient at suppressing the dogs’ immune responses.

The researchers are continuing to analyze the effects of bacterial infection on immune system cells known as macrophages to determine how the bacteria could breach the blood-brain barrier. Later, they will extend their studies to examining how the bacteria interact with different types of brain cells.

“The study is intriguing, but more work needs to be completed to determine the significance of these bacteria as a possible cause of GME and NME,” said Karen Vernau, an associate clinical professor and chief of neurology/neurosurgery at the University of California, Davis’ College of Veterinary Medicine, who was not involved in the study.