Christopher J. Martyniuk

Associate ProfessorMartyniukChris_200px

Center for Environmental and Human Toxicology &
Department of Physiological Sciences
2187 Mowry Road, Bldg 471
PO Box 110885
Gainesville, FL 32611
Office: 352-294-4636
Fax: 352-392-4707


  • PhD Biology, University of Ottawa, Ottawa, ON, CAN
  • MSc Zoology, University of Guelph, Guelph, ON, CAN
  • BSc Biology, Simon Fraser University, Burnaby, BC, CAN

Courses Taught in College of Veterinary Medicine

  • VME 6603 Advanced Toxicology (Fall)
  • VEM 5176 Poisonous Plants (Spring)
  • VEM 5172 Veterinary Toxicology (Fall)

National and International Awards

  • 2013: The Gorbman – Bern New Independent Investigator Award. North American Society for Comparative Endocrinology
  • 2013: Canadian Society of Zoology, Bob Boutilier New Investigator Award

Research Interests

Toxicology, Neuroendocrinology, Neurogenic Hypertension, Transcriptomics, Proteomics, Endocrine Disruption

Current Projects

  • Adverse outcome pathways for mitochondrial dysfunction (D. Dreier)
  • Polycyclic aromatic hydrocarbons and the reproductive axis (J Loughery)
  • Effects of toxaphene on the mitochondrial bioenergetics of zebrafish (V. Perez)
  • Developmental effects of dipyridyl herbicides in zebrafish (H. Wang)
  • Phthalates as obesogens: Microbiome-host interactions (Dr. O. Adamovsky)
  • UV stabilizers and metabolic profiling in zebrafish (Dr. X. Liang)
  • Hybrid nanoparticles and behavior (Dr. L. Zhao)
  • Microbiome responses in the gut to legacy pesticides (Dr. H. Qing)

Recent Publications

Liang X, Feswick A, Simmons D, Martyniuk CJ. Environmental toxicology and omics: A question of sex. J Proteomics. 2017 Oct 13. pii: S1874-3919(17)30326-3. doi: 10.1016/j.jprot.2017.09.010.

Wang XH, Souders CL 2nd, Zhao YH, Martyniuk CJ. Paraquat affects mitochondrial bioenergetics, dopamine system expression, and locomotor activity in zebrafish (Danio rerio). Chemosphere. 2017 Oct 6;191:106-117. doi: 10.1016/j.chemosphere.2017.10.032.

Liang X, Souders CL 2nd, Zhang J, Martyniuk CJ. Tributyltin induces premature hatching and reduces locomotor activity in zebrafish (Danio rerio) embryos/larvae at environmentally relevant levels. Chemosphere. 2017 Dec;189:498-506. doi:10.1016/j.chemosphere.2017.09.093.

Huang T, Yan L, Zheng S, Wang Y, Wang X, Fan L, Li C, Zhao Y, Martyniuk CJ. Discriminating modes of toxic action in mice using toxicity in BALB/c mouse fibroblast (3T3) cells. Chemosphere. 2017 Dec;188:73-80. doi:10.1016/j.chemosphere.2017.08.135.

Levin M, Martyniuk CJ. The bioelectric code: An ancient computational medium for dynamic control of growth and form. Biosystems. 2017 Sep 2. pii:S0303-2647(17)30284-8. doi:10.1016/j.biosystems.2017.08.009.

Schmidt JT, Rushin A, Boyda J, Souders CL 2nd, Martyniuk CJ. Dieldrin-induced neurotoxicity involves impaired mitochondrial bioenergetics and an endoplasmic reticulum stress response in rat dopaminergic cells. Neurotoxicology. 2017 Aug 24;63:1-12. doi: 10.1016/j.neuro.2017.08.007.

Paullin T, Powell C, Menzie C, Hill R, Cheng F, Martyniuk CJ, Westerheide SD. Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses. PLoS One. 2017 Aug 9;12(8):e0182930. doi:10.1371/journal.pone.0182930.

Dreier DA, Denslow ND, Martyniuk CJ. Computational analysis of the ToxCast estrogen receptor agonist assays to predict vitellogenin induction by chemicals in male fish. Environ Toxicol Pharmacol. 2017 Jul;53:177-183. doi:10.1016/j.etap.2017.05.015.

Mudge JF, Martyniuk CJ, Houlahan JE. Optimal alpha reduces error rates in gene expression studies: a meta-analysis approach. BMC Bioinformatics. 2017 Jun 21;18(1):312. doi: 10.1186/s12859-017-1728-3.

Liang X, Zha J, Martyniuk CJ, Wang Z, Zhao J. Histopathological and proteomic responses in male Chinese rare minnow (Gobiocypris rarus) indicate hepatotoxicity following benzotriazole exposure. Environ Pollut. 2017 Oct;229:459-469. doi:10.1016/j.envpol.2017.06.013. Epub 2017 Jun 30. PubMed PMID: 28624627.

Jones ER, Martyniuk CJ, Morris JM, Krasnec MO, Griffitt RJ. Exposure to Deepwater Horizon oil and Corexit 9500 at low concentrations induces transcriptional changes and alters immune transcriptional pathways in sheepshead minnows. Comp Biochem Physiol Part D Genomics Proteomics. 2017 Sep;23:8-16. doi:

Zubcevic J, Baker A, Martyniuk CJ. Transcriptional networks in rodent models support a role for gut-brain communication in neurogenic hypertension: a review of the evidence. Physiol Genomics. 2017 Jul 1;49(7):327-338. doi:10.1152/physiolgenomics.00010.2017.

Marjan P, Bragg LM, MacLatchy DL, Servos MR, Martyniuk CJ. How Does Reference Site Selection Influence Interpretation of Omics Data?: Evaluating Liver Transcriptome Responses in Male Rainbow Darter (Etheostoma caeruleum) across an Urban Environment. Environ Sci Technol. 2017 Jun 6;51(11):6470-6479. doi:10.1021/acs.est.7b00894.

Liang X, Li J, Martyniuk CJ, Wang J, Mao Y, Lu H, Zha J. Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere. 2017 Sep;182:22-30. doi:10.1016/j.chemosphere.2017.05.015.

Slade L, Cowie A, Martyniuk CJ, Kienesberger PC, Pulinilkunnil T. Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio). J Pharmacol Exp Ther. 2017 Jun;361(3):375-385. doi: 10.1124/jpet.116.239806.

Yang T, Ahmari N, Schmidt JT, Redler T, Arocha R, Pacholec K, Magee KL, Malphurs W, Owen JL, Krane GA, Li E, Wang GP, Vickroy TW, Raizada MK, Martyniuk CJ, Zubcevic J. Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon. Front Physiol. 2017 Apr 12;8:220.
doi: 10.3389/fphys.2017.00220.

Zhang JL, Laurence Souders C 2nd, Denslow ND, Martyniuk CJ. Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval zebrafish (Danio rerio). Toxicol Appl Pharmacol. 2017 Jul 15;327:30-38. doi: 10.1016/j.taap.2017.04.024.

Feswick A, Isaacs M, Biales A, Flick RW, Bencic DC, Wang RL, Vulpe C, Brown-Augustine M, Loguinov A, Falciani F, Antczak P, Herbert J, Brown L, Denslow ND, Kroll KJ, Lavelle C, Dang V, Escalon L, Garcia-Reyero N, Martyniuk CJ, Munkittrick KR. How consistent are we? Interlaboratory comparison study in fathead minnows using the model estrogen 17α-ethinylestradiol to develop recommendations for environmental transcriptomics. Environ Toxicol Chem. 2017 Oct;36(10):2614-2623. doi: 10.1002/etc.3799.

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Last updated 12 Mar 2017

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